نتائج البحث

One size does not fit all: Lysosomes exist in biochemically and functionally distinct states.

• Authors : Bussi, Claudio¹ (AUTHOR) ; Gutierrez, Maximiliano G.¹ (AUTHOR)

• Source: PLoS Biology. 3/22/2024, Vol. 22 Issue 3, p1-5. 5p.

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Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.

• Authors : Zeng, Wenping¹ (AUTHOR); Li, Canjun^1,2 (AUTHOR); Wu, Ruikun^3,4 (AUTHOR)

• Source: PLoS Biology. 4/23/2024, Vol. 22 Issue 4, p1-26. 26p.

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Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.

• Authors : Mamais, Adamantios^1,2 (AUTHOR); Kluss, Jillian H.¹ (AUTHOR); Bonet-Ponce, Luis¹ (AUTHOR)

• Source: PLoS Biology. 12/16/2021, Vol. 19 Issue 12, p1-30. 30p. 2 Charts, 7 Graphs.

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Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.

• Authors : Li, Chuang¹ (AUTHOR); Fu, Jiaqi¹ (AUTHOR); Shao, Shuai^2,3 (AUTHOR)

• Source: PLoS Pathogens. 5/13/2024, Vol. 20 Issue 5, p1-29. 29p.

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Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.

• Authors : Zheng, Weihao¹ (AUTHOR); Chang, I-Chang¹ (AUTHOR); Limberis, Jason¹ (AUTHOR)

• Source: PLoS Pathogens. 5/3/2024, Vol. 20 Issue 5, p1-32. 32p.

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LRK-1/LRRK2 and AP-3 regulate trafficking of synaptic vesicle precursors through active zone protein SYD-2/Liprin-α.

• Authors : Nadiminti SSP; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, Maharashtra, India.; Dixit SB

Subjects: Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/metabolism ; Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics

• Source: PLoS genetics [PLoS Genet] 2024 May 09; Vol. 20 (5), pp. e1011253. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection

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Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes.

• Authors : Domert, Jakob¹; Sackmann, Christopher¹; Severinsson, Emelie¹

Subjects: *ALPHA-synuclein; *NEURONS; *LYSOSOMES

• Source: PLoS ONE. 12/28/2016, Vol. 11 Issue 12, p1-16. 16p.

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Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo.

• Authors : MacLeod, Collin M.¹ (AUTHOR); Yousufzai, Fawad A. K.² (AUTHOR); Spencer, Liam T.¹ (AUTHOR)

Subjects: *LYSOSOMES; *PURKINJE cells; *TREHALOSE

• Source: PLoS ONE. 11/30/2023, Vol. 18 Issue 11, p1-18. 18p.

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Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress.

• Authors : Pascua-Maestro, Raquel¹ ; Diez-Hermano, Sergio¹; Lillo, Concepción²

• Source: PLoS Genetics. 2/9/2017, Vol. 13 Issue 2, p1-33. 33p.

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Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes.

• Authors : Castro-Gomes, Thiago¹; Corrotte, Matthias¹; Tam, Christina¹

Subjects: *LYSOSOMES; *CELL membranes; *PROTEOLYTIC enzymes

• Source: PLoS ONE. 3/30/2016, Vol. 11 Issue 3, p1-26. 26p.

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