نتائج البحث

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells.

• Authors : Bao, Qi^1,2,3 (AUTHOR); Wang, Zihan¹ (AUTHOR); Yang, Tingting⁴ (AUTHOR)

Subjects: *Ovaries; *Cell cycle; *Ovarian cancer

• Source: PLoS ONE. 3/31/2025, Vol. 20 Issue 3, p1-18. 18p.

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Fischer's ratio and DNA damage in hypoxemia-induced brain injury in rat model: prophylactic role of quercetin and mexamine supplementation.

• Authors : Kadry, Mai O.¹ (AUTHOR); Ali, Hanaa² (AUTHOR)

Subjects: *LABORATORY rats; *BRAIN damage; *BRAIN injuries

• Source: PLoS ONE. 3/18/2025, Vol. 20 Issue 3, p1-19. 19p.

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Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response.

• Authors : Ting, Kenneth K.Y.^1,2 (AUTHOR); Ibrahim, Hisham M.^2,3 (AUTHOR); Gulati, Nitya² (AUTHOR)

Subjects: *FOAM cells; *GENE expression; *REACTIVE oxygen species

• Source: PLoS ONE. 3/5/2025, Vol. 20 Issue 3, p1-22. 22p.

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Capsicum chinense Jacq. fruit plays an immunomodulatory role in cytokine attenuation and DNA damage protection.

• Authors : Saha, Srabonti¹ (AUTHOR); Hossain, Md. Altaf¹ (AUTHOR); Ferdousi, Humayra¹ (AUTHOR)

Subjects: *HeLa cells; *DNA damage; *Cytotoxins

• Source: PLoS ONE. 2/25/2025, Vol. 20 Issue 2, p1-24. 24p.

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The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells.

• Authors : Li, Yating¹ (AUTHOR); Wang, Xing¹ (AUTHOR); Liu, Xiaolong¹ (AUTHOR)

Subjects: *GENE expression; *CELL migration; *STOMACH cancer

• Source: PLoS ONE. 12/31/2024, Vol. 19 Issue 12, p1-15. 15p.

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Progerin can induce DNA damage in the absence of global changes in replication or cell proliferation.

• Authors : Joudeh, Liza A.¹ (AUTHOR); Schuck, P. Logan¹ (AUTHOR); Van, Nina M.¹ (AUTHOR)

Subjects: *Progeria; *Double-strand DNA breaks; *Progerin

• Source: PLoS ONE. 12/5/2024, Vol. 19 Issue 12, p1-18. 18p.

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Computational modelling identifies primary mediators of crosstalk between DNA damage and oxidative stress responses.

• Authors : Burgers EJ; Division of Cell Systems and Drug Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Sharma RP

Subjects: DNA Damage*/DNA Damage*/DNA Damage*/physiology ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/physiology ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects

• Source: PLoS computational biology [PLoS Comput Biol] 2025 Mar 10; Vol. 21 (3), pp. e1012844. Date of Electronic Publication: 2025 Mar 10 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection

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Caspase 3 and caspase 7 promote cytoprotective autophagy and the DNA damage response during non-lethal stress conditions in human breast cancer cells.

• Authors : Samarasekera G; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

Subjects: Autophagy*/Autophagy*/Autophagy*/physiology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics

• Source: PLoS biology [PLoS Biol] 2025 Feb 21; Vol. 23 (2), pp. e3003034. Date of Electronic Publication: 2025 Feb 21 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection

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Anthelmintic effects of some medicinal plants on different life stages of Fasciola hepatica: Evidence on oxidative stress biomarkers, and DNA damage.

• Authors : Allahyari, Mohaddeseh¹ (AUTHOR); Malekifard, Farnaz¹ (AUTHOR) ; Yakhchali, Mohammad¹ (AUTHOR)

• Source: PLoS Neglected Tropical Diseases. 6/17/2024, Vol. 18 Issue 6, p1-14. 14p.

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Evaluation of genotoxic effect via expression of DNA damage responsive gene induced by ivermectin on MDBK cell line.

• Authors : Ali, Muhammad Muddassir¹ (AUTHOR) ; Farhad, Zainab¹ (AUTHOR); Wasim, Muhammad¹ (AUTHOR)

Subjects: *GENETIC toxicology; *GENE expression; *DNA repair

• Source: PLoS ONE. 5/3/2024, Vol. 19 Issue 5, p1-11. 11p.

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