نتائج البحث

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors.

• Authors : Meijles, Daniel N.^1,2; Fuller, Stephen J.¹; Cull, Joshua J.¹

Subjects: *PROTEIN kinase B; *SOMATOMEDIN; *PROTEIN receptors

• Source: Biochemical Journal. Jun2021, Vol. 478 Issue 11, p2059-2079. 21p.

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Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors.

• Authors : Melick, Chase H.^1,2,3; Jewell, Jenna L.^1,2,3

Subjects: *MTOR inhibitors; *SMALL molecules; *PHOSPHORYLATION

• Source: Biochemical Journal. May2020, Vol. 477 Issue 10, p1847-1863. 17p.

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Retraction: Downregulated microRNA-30b-3p inhibits proliferation, invasion and migration of glioma cells via inactivation of the AKT signaling pathway by upregulating RECK

• Source: Bioscience Reports ; volume 44, issue 5 ; ISSN 0144-8463 1573-4935

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Lipid-dependent Akt-ivity: where, when, and how.

• Authors : Siess, Katharina M.^1,2; Leonard, Thomas A.^1,2

Subjects: *INTRACELLULAR membranes; *CELL membranes; *PROTEIN kinases

• Source: Biochemical Society Transactions. 6/28/2019, Vol. 47 Issue 3, p897-908. 12p.

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Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.

• Authors : Hussain, Nusrat¹; Sheng-Ju Chuang¹; Johanns, Manuel¹

Subjects: *WHITE adipose tissue; *ALLOSTERIC proteins; *PROTEIN kinase B

• Source: Biochemical Journal. Apr2020, Vol. 477 Issue 8, p1378-1369. 17p.

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Nutlin-3 plus tanshinone IIA exhibits synergetic anti-leukemia effect with imatinib by reactivating p53 and inhibiting the AKT/mTOR pathway in Ph+ ALL.

• Authors : Yong Guo¹ (AUTHOR); Yi Li² (AUTHOR); Bing Xiang¹ (AUTHOR)

• Source: Biochemical Journal. 12/15/2017, Vol. 474 Issue 24, p4153-4170. 18p. 1 Black and White Photograph, 1 Chart, 7 Graphs.

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Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response.

• Authors : Chan, Tung O.^1,2,3 ; Jin Zhang¹; Tiegs, Brian C.¹

Subjects: *PROTEIN kinase B; *ADENOSINE triphosphate; *DEPHOSPHORYLATION

• Source: Biochemical Journal. 10/1/2015, Vol. 471 Issue 1, p37-51. 15p.

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Development of a new model system to dissect isoform specific Akt signalling in adipocytes.

• Authors : Kajno, Esi¹; McGraw, Timothy E.¹; Gonzalez, Eva¹

Subjects: *PROTEIN kinase B; *CELLULAR signal transduction; *FAT cells

• Source: Biochemical Journal. 6/15/2015, Vol. 468 Issue 3, p425-434. 10p.

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Akt/PKB: one kinase, many modifications.

• Authors : Risso, Guillermo¹; Blaustein, Matías¹; Pozzi, Berta¹

Subjects: *PROTEIN kinase B; *PLETHORA (Pathology); *POST-translational modification

• Source: Biochemical Journal. 6/1/2015, Vol. 468 Issue 2, p203-214. 12p.

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Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways.

• Authors : Jianjun Ma¹; Yan Ma¹; Xuqiang Liu²

Subjects: *DISEASE risk factors; *OSTEOPOROSIS; *OVARIECTOMY

• Source: Biochemical Journal. 2015, Vol. 469 Issue 3, p399-408. 10p.

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