نتائج البحث

A single-cell map of antisense oligonucleotide activity in the brain.

• Authors : Mortberg, Meredith A¹ (AUTHOR); Gentile, Juliana E¹ (AUTHOR); Nadaf, Naeem M¹ (AUTHOR)

Subjects: *CENTRAL nervous system; *CEREBROSPINAL fluid

• Source: Nucleic Acids Research. 8/11/2023, Vol. 51 Issue 14, p7109-7124. 16p.

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Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice.

• Authors : Desjardins, Cody A¹ (AUTHOR); Yao, Monica¹ (AUTHOR); Hall, John¹ (AUTHOR)

Subjects: *DYSTROPHIN; *DUCHENNE muscular dystrophy; *TRANSFERRIN receptors

• Source: Nucleic Acids Research. 11/11/2022, Vol. 50 Issue 20, p11401-11414. 14p.

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The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration.

• Authors : Jafar-nejad, Paymaan¹ (AUTHOR); Powers, Berit¹ (AUTHOR); Soriano, Armand¹ (AUTHOR)

Subjects: *RIBONUCLEASE H; *SPINAL muscular atrophy; *CENTRAL nervous system

• Source: Nucleic Acids Research. 1/25/2021, Vol. 49 Issue 2, p657-673. 17p.

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Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells.

• Authors : Michaels, Wren E^1,2 (AUTHOR); Bridges, Robert J¹ (AUTHOR) ; Hastings, Michelle L¹ (AUTHOR)

Subjects: *CYSTIC fibrosis; *EPITHELIAL cells; *SECRETION

• Source: Nucleic Acids Research. 7/27/2020, Vol. 48 Issue 13, p7454-7467. 14p.

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Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2ʹ-MOE-Modified Antisense Oligonucleotide.

• Authors : Narayanan, Padmakumar¹ ; Shen, Lijiang¹; Curtis, Brian R²

Subjects: *BLOOD platelets; *KRA; *OLIGONUCLEOTIDES

• Source: Toxicological Sciences. Aug2018, Vol. 164 Issue 2, p613-626. 14p. 10 Graphs.

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A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.

• Authors : Ochaba, Joseph¹ (AUTHOR); Powers, Andrew F¹ (AUTHOR); Tremble, Kaitlyn A¹ (AUTHOR)

Subjects: *KETOGENIC diet; *GROWTH factors; *CELL membranes

• Source: Nucleic Acids Research. 12/2/2019, Vol. 47 Issue 21, p11284-11303. 20p.

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Therapeutic effect of intracolonically administered nuclear factor κB (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis.

• Authors : Murano, M.¹; Maemura, K.¹; Hirata, I.¹

Subjects: *NF-kappa B; *OLIGONUCLEOTIDES; *COLITIS

• Source: Clinical & Experimental Immunology. Apr2000, Vol. 120 Issue 1, p51-58. 8p.

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RNase H sequence preferences influence antisense oligonucleotide efficiency.

• Authors : Kie-lpiński, Lukasz J.¹ (AUTHOR) ; Hagedorn, Peter H.¹ (AUTHOR); Lindow, Morten¹ (AUTHOR)

• Source: Nucleic Acids Research. 12/15/2017, Vol. 45 Issue 22, p12932-12944. 13p. 1 Chart, 5 Graphs.

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CCL20 Is Negatively Regulated by TGF-β1 in Intestinal Epithelial Cells and Reduced in Crohn’s Disease Patients With a Successful Response to Mongersen, a Smad7 Antisense Oligonucleotide.

• Authors : Marafini, Irene¹ (AUTHOR); Monteleone, Ivan¹ (AUTHOR); Dinallo, Vincenzo¹ (AUTHOR)

• Source: Journal of Crohn's & Colitis. May2017, Vol. 11 Issue 5, p603-609. 7p. 4 Graphs.

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Inhibition of Endogenous Expression of Connective Tissue Growth Factor by Its Antisense Oligonucleotide and Antisense RNA Suppresses Proliferation and Migration of Vascular Endothelial Cells1.

• Authors : Shimo, Tsuyoshi¹; Nakanishi, Tohru¹; Kimura, Yusuke¹

Subjects: *ANTISENSE nucleic acids; *MUSCULOSKELETAL system; *CONNECTIVE tissues

• Source: Journal of Biochemistry. 1998, Vol. 124 Issue 1, p130-140. 11p.

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