نتائج البحث

Genomic profiling of six human somatic histone H1 variants denotes that H1X accumulates at recently incorporated transposable elements.

• Authors : Salinas-Pena, Mónica¹ (AUTHOR); Serna-Pujol, Núria¹ (AUTHOR); Jordan, Albert¹ (AUTHOR)

Subjects: *NUCLEAR DNA; *HUMAN genome; *CELL lines

• Source: Nucleic Acids Research. 2/28/2024, Vol. 52 Issue 4, p1793-1813. 21p.

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The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops.

• Authors : Wang, Yajun^1,2 (AUTHOR); Zhu, Wei¹ (AUTHOR); Jang, Yumi³ (AUTHOR)

Subjects: *RNA-binding proteins; *TELOMERES; *DNA replication

• Source: Nucleic Acids Research. 12/11/2023, Vol. 52 Issue 22, p12242-12260. 19p.

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TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.

• Authors : Jaiswal, Aruna S¹ (AUTHOR); Dutta, Arijit² (AUTHOR); Srinivasan, Gayathri¹ (AUTHOR)

Subjects: *EXONUCLEASES; *CANCER cells; *DOUBLE-stranded RNA

• Source: Nucleic Acids Research. 12/11/2023, Vol. 52 Issue 22, p12224-12241. 18p.

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BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells.

• Authors : Wang, Xuepeng¹ (AUTHOR); Song, Chengcheng² (AUTHOR); Ye, Ying³ (AUTHOR)

Subjects: *HUMAN embryonic stem cells; *CANCER stem cells; *CANCER cells

• Source: Nucleic Acids Research. 11/27/2023, Vol. 51 Issue 21, p11634-11651. 18p.

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Correction to 'MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis'.

Subjects: *TUMOR growth; *MICRORNA; *CANCER cells

• Source: Nucleic Acids Research. 11/10/2023, Vol. 51 Issue 20, p11403-11406. 4p.

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Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.

• Authors : Wang, Zhijia¹ (AUTHOR); Himanen, Samu V² (AUTHOR); Haikala, Heidi M^3,4 (AUTHOR)

Subjects: *RNA polymerase II; *CYCLIN-dependent kinases; *CANCER cells

• Source: Nucleic Acids Research. 11/10/2023, Vol. 51 Issue 20, p10970-10991. 22p.

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Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA.

• Authors : Sénéchal, Ronan Le¹ (AUTHOR); Keruzoré, Marc¹ (AUTHOR); Quillévéré, Alicia¹ (AUTHOR)

Subjects: *ALTERNATIVE RNA splicing; *CANCER cells; *CANCER chemotherapy

• Source: Nucleic Acids Research. 11/10/2023, Vol. 51 Issue 20, p11239-11257. 19p.

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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

• Authors : Krishnan, Rehna¹ (AUTHOR); Lapierre, Mariah^1,2 (AUTHOR); Gautreau, Brandon^1,2 (AUTHOR)

Subjects: *BRCA genes; *UBIQUITINATION; *CANCER cells

• Source: Nucleic Acids Research. 10/27/2023, Vol. 51 Issue 19, p10484-10505. 22p.

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ZEB1 promotes non-homologous end joining double-strand break repair.

• Authors : Genetta, Thomas L¹ (AUTHOR) ; Hurwitz, Joshua C¹ (AUTHOR); Clark, Evan A¹ (AUTHOR)

Subjects: *CANCER cells; *POLY(ADP-ribose) polymerase; *BIOMARKERS

• Source: Nucleic Acids Research. 10/13/2023, Vol. 51 Issue 18, p9863-9879. 17p.

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Deciphering a global source of non-genetic heterogeneity in cancer cells.

• Authors : Zhang, Jianhan^1,2 (AUTHOR); Han, Xu^1,2 (AUTHOR); Ma, Liang^1,2 (AUTHOR)

Subjects: *CANCER cells; *CLONE cells; *HETEROGENEITY

• Source: Nucleic Acids Research. 9/22/2023, Vol. 51 Issue 17, p9019-9038. 20p.

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