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Academic Journal

A novel framework integrating AI model and enzymological experiments promotes identification of SARS-CoV-2 3CL protease inhibitors and activity-based probe.

  • Authors : Hu F; Guangdong-Hong Kong-Macao Joint Laboratory of Human-Machine Intelligence-Synergy Systems, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.; Wang L

Subjects: COVID-19 Drug Treatment*; Protease Inhibitors/Protease Inhibitors/Protease Inhibitors/*chemistry ; SARS-CoV-2/SARS-CoV-2/SARS-CoV-2/*chemistry

  • Source: Briefings in bioinformatics [Brief Bioinform] 2021 Nov 05; Vol. 22 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium:

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Academic Journal

Protease inhibitors elicit anti-inflammatory effects in CF mice with Pseudomonas aeruginosa acute lung infection.

  • Authors : Sandri A; Department of Diagnostics and Public Health, Section of Microbiology, University of Verona, Verona, Italy.; Lleo MM

Subjects: Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*drug therapy ; Hydroxamic Acids/Hydroxamic Acids/Hydroxamic Acids/*pharmacology ; Indoles/Indoles/Indoles/*pharmacology

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2021 Jan; Vol. 203 (1), pp. 87-95. Date of Electronic Publication: 2020 Oct 12.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print-Electronic Cited

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Academic Journal

β-Trefoil structure enables interactions between lectins and protease inhibitors that regulate their biological functions.

  • Authors : Žurga S; Department of Biotechnology, Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana, Slovenia; and Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.

Subjects: Lectins/Lectins/Lectins/*chemistry ; Peptides/Peptides/Peptides/*chemistry ; Protease Inhibitors/Protease Inhibitors/Protease Inhibitors/*chemistry

  • Source: Journal of biochemistry [J Biochem] 2015 Jul; Vol. 158 (1), pp. 83-90. Date of Electronic Publication: 2015 Mar 04.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print-Electronic Cited

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Academic Journal

A New, Rapid and Simple RP-HPLC Method for Stability Quantification of a Protease Inhibitor in Tablets.

  • Authors : Rossi RC; Faculty of Pharmacy, Health School, Universidade do Vale do Rio dos Sinos, Av. Unisinos, 950, São Leopoldo CEP 93022-750, Brazil.; Moura JGL

Subjects: Antiviral Agents* ; Protease Inhibitors*; Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/methods

  • Source: Journal of chromatographic science [J Chromatogr Sci] 2022 Sep 03; Vol. 60 (7), pp. 671-677.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited

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Academic Journal

Simultaneous quantitation of HIV-protease inhibitors ritonavir, lopinavir and indinavir in human plasma by UPLC-ESI-MS-MS.

  • Authors : Das Mishra T; Bioanalytical Research Department, Veeda Clinical Research, Ambawadi, Ahmedabad 380015, India.; Kurani H

Subjects: Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/*methods ; HIV Protease Inhibitors/HIV Protease Inhibitors/HIV Protease Inhibitors/*blood ; Indinavir/Indinavir/Indinavir/*blood

  • Source: Journal of chromatographic science [J Chromatogr Sci] 2012 Aug; Vol. 50 (7), pp. 625-35. Date of Electronic Publication: 2012 May 04.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print-Electronic

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Periodical

HCV protease inhibitors bring new options for patients.

Subjects: Hepacivirus/Hepacivirus/Hepacivirus/*drug effects ; Hepatitis C, Chronic/Hepatitis C, Chronic/Hepatitis C, Chronic/*drug therapy ; Protease Inhibitors/Protease Inhibitors/Protease Inhibitors/*therapeutic use

  • Source: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2011 Aug 01; Vol. 68 (15), pp. 1372, Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium:

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Academic Journal

Simplifying the treatment of HIV infection with ritonavir-boosted protease inhibitors in antiretroviral-experienced patients.

  • Authors : Scott JD; Western University of Health Sciences, 309 East 2nd Street, Pomona, CA 91766, USA.

Subjects: HIV Infections/HIV Infections/HIV Infections/*drug therapy ; HIV Protease Inhibitors/HIV Protease Inhibitors/HIV Protease Inhibitors/*therapeutic use ; Ritonavir/Ritonavir/Ritonavir/*therapeutic use

  • Source: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2005 Apr 15; Vol. 62 (8), pp. 809-15.Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium:

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Academic Journal

A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation.

  • Authors : Rakib A; Department of Pharmaceutical Sciences, College of Pharmacy, 881 Madison Ave, Memphis, TN 38163, USA.; Nain Z

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Coronavirus 3C Proteases/Coronavirus 3C Proteases/Coronavirus 3C Proteases/*antagonists & inhibitors ; Heterocyclic Compounds/Heterocyclic Compounds/Heterocyclic Compounds/*pharmacology

  • Source: Briefings in bioinformatics [Brief Bioinform] 2021 Mar 22; Vol. 22 (2), pp. 1476-1498.Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium:

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