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  • 1-10 ل  10 نتائج ل ""Myeloid Cell Leukemia Sequence 1 Protein""
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Academic Journal

Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models.

  • Authors : Zhang H; Department of Medicine, Roswell Park Cancer Institute, Elm & Carlton streets, Buffalo, NY 14263, USA.; Hylander BL

Subjects: Pancreatic Neoplasms/Pancreatic Neoplasms/Pancreatic Neoplasms/*drug therapy ; Pancreatic Neoplasms/Pancreatic Neoplasms/Pancreatic Neoplasms/*metabolism ; Receptor, Fibroblast Growth Factor, Type 2/Receptor, Fibroblast Growth Factor, Type 2/Receptor, Fibroblast Growth Factor, Type 2/*antagonists & inhibitors

  • Source: British journal of cancer [Br J Cancer] 2014 Jan 21; Vol. 110 (2), pp. 320-9. Date of Electronic Publication: 2013 Dec 10.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours.

  • Authors : Zhang X; Drug Discovery Department, Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.; Blaskovich MA

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Ergosterol/Ergosterol/Ergosterol/*analogs & derivatives

  • Source: British journal of cancer [Br J Cancer] 2014 Aug 26; Vol. 111 (5), pp. 894-902. Date of Electronic Publication: 2014 Jul 01.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance.

  • Authors : Kaliszczak M; Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.; Patel H

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism ; ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/*metabolism ; Cyclin-Dependent Kinases/Cyclin-Dependent Kinases/Cyclin-Dependent Kinases/*antagonists & inhibitors

  • Source: British journal of cancer [Br J Cancer] 2013 Oct 29; Vol. 109 (9), pp. 2356-67. Date of Electronic Publication: 2013 Sep 26.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1.

  • Authors : Zhang Z; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian 116024, China. ; Liu Y

Subjects: Acenaphthenes/Acenaphthenes/Acenaphthenes/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Leukemia/Leukemia/Leukemia/*metabolism

  • Source: British journal of cancer [Br J Cancer] 2013 May 14; Vol. 108 (9), pp. 1870-8. Date of Electronic Publication: 2013 Apr 04.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Eukaryotic Initiation Factor-4F/Eukaryotic Initiation Factor-4F/Eukaryotic Initiation Factor-4F/*antagonists & inhibitors ; Multiple Myeloma/Multiple Myeloma/Multiple Myeloma/*drug therapy

  • Source: British journal of cancer [Br J Cancer] 2012 May 08; Vol. 106 (10), pp. 1660-7. Date of Electronic Publication: 2012 Apr 17.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells.

  • Authors : Pervin S; Department of Internal Medicine, Charles Drew University of Medicine and Science, 3084 Hawkins Building, 1731 East 120th Street, Los Angeles, CA 90059, USA. ; Tran A

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*chemistry ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/*chemistry

  • Source: British journal of cancer [Br J Cancer] 2011 Jul 26; Vol. 105 (3), pp. 428-37. Date of Electronic Publication: 2011 Jul 05.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation.

  • Authors : Spagnuolo C; Institute of Food Sciences, National Research Council, 83100 Avellino 83100 Avellino, Italy.; Cerella C

Subjects: Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/*genetics ; Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/*metabolism ; Quercetin/Quercetin/Quercetin/*pharmacology

  • Source: British journal of cancer [Br J Cancer] 2011 Jul 12; Vol. 105 (2), pp. 221-30.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Stat3 activation in human endometrial and cervical cancers.

  • Authors : Chen CL; Center for Childhood Cancer, Columbus Children's Research Institute, Columbus, OH 43205, USA.; Hsieh FC

Subjects: Endometrial Neoplasms/Endometrial Neoplasms/Endometrial Neoplasms/*metabolism ; STAT3 Transcription Factor/STAT3 Transcription Factor/STAT3 Transcription Factor/*metabolism ; Uterine Cervical Neoplasms/Uterine Cervical Neoplasms/Uterine Cervical Neoplasms/*metabolism

  • Source: British journal of cancer [Br J Cancer] 2007 Feb 26; Vol. 96 (4), pp. 591-9.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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Academic Journal

Apoptotic activity is increased in parallel with the metaplasia-dysplasia-carcinoma sequence of the bronchial epithelium.

Subjects: Apoptosis*; Bronchi/Bronchi/Bronchi/*pathology ; Carcinoma in Situ/Carcinoma in Situ/Carcinoma in Situ/*pathology

  • Source: British journal of cancer [Br J Cancer] 1999 Feb; Vol. 79 (5-6), pp. 996-1002.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication

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