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Academic Journal

Suppression of the TGF-β signaling exacerbates degeneration of auditory neurons in kanamycin-induced ototoxicity in mice.

  • Authors : Nitta Y; Department of Otorhinolaryngology and Head and Neck Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan. .; Kurioka T

Subjects: Kanamycin*/Kanamycin*/Kanamycin*/toxicity ; Ototoxicity*/Ototoxicity*/Ototoxicity*/etiology ; Ototoxicity*/Ototoxicity*/Ototoxicity*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 May 13; Vol. 14 (1), pp. 10910. Date of Electronic Publication: 2024 May 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers.

  • Authors : Generotti C; Department of Otolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, 421 Curie Blvd., BRB 1212, Philadelphia, PA, 19104, USA.; Cox BC

Subjects: Ototoxicity*/Ototoxicity*/Ototoxicity*/diagnosis ; Ototoxicity*/Ototoxicity*/Ototoxicity*/etiology ; Hearing Loss*/Hearing Loss*/Hearing Loss*/chemically induced

  • Source: Scientific reports [Sci Rep] 2022 Oct 27; Vol. 12 (1), pp. 18032. Date of Electronic Publication: 2022 Oct 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity.

  • Authors : Paciello F; Department of Neuroscience, Università Cattolica del Sacro Cuore, Roma, Italia.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*adverse effects ; Cisplatin/Cisplatin/Cisplatin/*adverse effects

  • Source: Scientific reports [Sci Rep] 2020 Jan 23; Vol. 10 (1), pp. 1063. Date of Electronic Publication: 2020 Jan 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea.

  • Authors : Bhatta P; Departments of Pharmacology, Internal Medicine and Surgery, SIU School of Medicine, PO Box 19629, Springfield, IL, 62794, USA.; Dhukhwa A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Capsaicin/Capsaicin/Capsaicin/*pharmacology ; Cisplatin/Cisplatin/Cisplatin/*toxicity

  • Source: Scientific reports [Sci Rep] 2019 Mar 11; Vol. 9 (1), pp. 4131. Date of Electronic Publication: 2019 Mar 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.

  • Authors : Ishikawa M; Molecular Physiology of Hearing, Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), University of Tübingen, Tübingen, Germany.; Graduate School of Medicine, Department of Otolaryngology, Kyoto University, Kyoto, Japan.

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*adverse effects ; Gentamicins/Gentamicins/Gentamicins/*pharmacology ; Hearing Loss/Hearing Loss/Hearing Loss/*genetics

  • Source: Scientific reports [Sci Rep] 2019 Feb 20; Vol. 9 (1), pp. 2410. Date of Electronic Publication: 2019 Feb 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity.

  • Authors : Gonçalves AC; UCL Ear Institute, University College London, 332 Gray's Inn Road, WC1X 8EE, London, UK.; Towers ER

Subjects: Aminoglycosides/Aminoglycosides/Aminoglycosides/*toxicity ; Cochlea/Cochlea/Cochlea/*drug effects ; Hair Cells, Auditory/Hair Cells, Auditory/Hair Cells, Auditory/*drug effects

  • Source: Scientific reports [Sci Rep] 2019 Aug 29; Vol. 9 (1), pp. 12501. Date of Electronic Publication: 2019 Aug 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

The genetic vulnerability to cisplatin ototoxicity: a systematic review.

  • Authors : Tserga E; Experimental Audiology, Biomedicum, Karolinska Institutet, Solnavägen 9, 171 65, Stockholm, Sweden.; Nandwani T

Subjects: Genetic Predisposition to Disease* ; Pharmacogenomic Variants*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*adverse effects

  • Source: Scientific reports [Sci Rep] 2019 Mar 05; Vol. 9 (1), pp. 3455. Date of Electronic Publication: 2019 Mar 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Detection of unknown ototoxic adverse drug reactions: an electronic healthcare record-based longitudinal nationwide cohort analysis.

  • Authors : Lee S; Department of Biomedical Informatics, College of Medicine, Konyang University, Daejeon, Republic of Korea.; Cha J

Subjects: Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/*complications ; Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/*epidemiology ; Ototoxicity/Ototoxicity/Ototoxicity/*epidemiology

  • Source: Scientific reports [Sci Rep] 2021 Jul 07; Vol. 11 (1), pp. 14045. Date of Electronic Publication: 2021 Jul 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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