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Academic Journal

Structure and dimerization properties of the plant-specific copper chaperone CCH.

  • Authors : Dluhosch D; Institute of Biochemical Plant Physiology, Heinrich-Heine-Universität Düsseldorf, 40225, Düsseldorf, Germany.; Kersten LS

Subjects: Copper*/Copper*/Copper*/metabolism ; Copper*/Copper*/Copper*/chemistry ; Molecular Chaperones*/Molecular Chaperones*/Molecular Chaperones*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 17; Vol. 14 (1), pp. 19099. Date of Electronic Publication: 2024 Aug 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer.

  • Authors : Kerschbaumer B; Institute of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010, Graz, Austria.; Macheroux P

Subjects: Protein Multimerization*; Phosphorylation ; Oxylipins/Oxylipins/Oxylipins/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 05; Vol. 14 (1), pp. 18093. Date of Electronic Publication: 2024 Aug 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Flavivirus Zika NS4A protein forms large oligomers in liposomes and in mild detergent.

  • Authors : Surya W; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore.; Honey SS

Subjects: Liposomes*/Liposomes*/Liposomes*/chemistry ; Liposomes*/Liposomes*/Liposomes*/metabolism ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/chemistry

  • Source: Scientific reports [Sci Rep] 2024 May 31; Vol. 14 (1), pp. 12533. Date of Electronic Publication: 2024 May 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Molecular mechanisms at the basis of the protective effect exerted by EPPS on neurodegeneration induced by prefibrillar amyloid oligomers.

  • Authors : Zarrilli B; Department of Systems Medicine, 'Tor vergata' University of Rome, Via Montpellier 1, 00133, Rome, Italy.; Laboratory of Experimental Neurology, IRCCS Fondazione Santa Lucia, Rome, Italy.

Subjects: Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism; Animals ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Nov 03; Vol. 14 (1), pp. 26533. Date of Electronic Publication: 2024 Nov 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation.

  • Authors : Nyamsuren G; Department of Nephrology and Rheumatology, Göttingen University Medical Center, Georg August University, Göttingen, Germany.; Rapp G

Subjects: Protein Multimerization*; Aryl Hydrocarbon Receptor Nuclear Translocator/Aryl Hydrocarbon Receptor Nuclear Translocator/Aryl Hydrocarbon Receptor Nuclear Translocator/*metabolism ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Scientific reports [Sci Rep] 2021 Dec 15; Vol. 11 (1), pp. 24075. Date of Electronic Publication: 2021 Dec 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Structural, energetic and lipophilic analysis of SARS-CoV-2 non-structural protein 9 (NSP9).

  • Authors : de O Araújo J; Laboratório de Planejamento e Desenvolvimento de Fármacos, Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, Rua Augusto Corrêa 01, 66075-110, Belém, Pará, Brasil.; Pinheiro S

Subjects: Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/chemistry ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/metabolism ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/genetics

  • Source: Scientific reports [Sci Rep] 2021 Nov 26; Vol. 11 (1), pp. 23003. Date of Electronic Publication: 2021 Nov 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Neuronal extracellular vesicles influence the expression, degradation and oligomeric state of fructose 1,6-bisphosphatase 2 in astrocytes affecting their glycolytic capacity.

  • Authors : Hajka D; Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335, Wrocław, Poland.; Łukasiewicz Research Network - PORT Polish Center for Technology Development, 54-006, Wrocław, Poland.

Subjects: Astrocytes*/Astrocytes*/Astrocytes*/metabolism ; Glycolysis* ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Sep 09; Vol. 14 (1), pp. 20932. Date of Electronic Publication: 2024 Sep 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress.

  • Authors : Wang Y; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), The University of Texas-Health Science Center at Houston, 1825 Pressler St., IMM-630A, Houston, TX, 77030, USA.; Lyu L

Subjects: Sequestosome-1 Protein*/Sequestosome-1 Protein*/Sequestosome-1 Protein*/metabolism ; Autophagy* ; Oxidative Stress*

  • Source: Scientific reports [Sci Rep] 2024 Aug 16; Vol. 14 (1), pp. 18974. Date of Electronic Publication: 2024 Aug 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation.

  • Authors : Xia Y; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, BMS J483/CTRND, 1275 Center Drive, Gainesville, FL, 32610, USA.

Subjects: Protein Multimerization* ; Protein Processing, Post-Translational*; Microtubules/Microtubules/Microtubules/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Aug 23; Vol. 11 (1), pp. 17069. Date of Electronic Publication: 2021 Aug 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Rational design of heterodimeric receptors capable of activating target signaling molecules.

  • Authors : Kongkrongtong T; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.; Zhang R

Subjects: Protein Multimerization* ; Signal Transduction*; Proto-Oncogene Proteins c-kit/Proto-Oncogene Proteins c-kit/Proto-Oncogene Proteins c-kit/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Aug 19; Vol. 11 (1), pp. 16809. Date of Electronic Publication: 2021 Aug 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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