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Academic Journal

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients.

  • Authors : Fekete F; Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok 2, Budapest, 1117, Hungary.; Doctoral School of Biology and Institute of Biology, Eötvös Loránd University, Pázmány Péter Sétány 1/A, Budapest, 1117, Hungary.

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/metabolism ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/adverse effects

  • Source: Scientific reports [Sci Rep] 2023 Oct 28; Vol. 13 (1), pp. 18507. Date of Electronic Publication: 2023 Oct 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

In silico screening and analysis of nonsynonymous SNPs in human CYP1A2 to assess possible associations with pathogenicity and cancer susceptibility.

  • Authors : Navapour L; Biophysics and Computational Biology Laboratory (BCBL), Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran.; Mogharrab N

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/chemistry ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics ; Genetic Predisposition to Disease*

  • Source: Scientific reports [Sci Rep] 2021 Mar 02; Vol. 11 (1), pp. 4977. Date of Electronic Publication: 2021 Mar 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia.

  • Authors : Menus Á; Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa 6, 1082, Budapest, Hungary.; Kiss Á

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*adverse effects ; Clozapine/Clozapine/Clozapine/*adverse effects ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Dec 04; Vol. 10 (1), pp. 21283. Date of Electronic Publication: 2020 Dec 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.

  • Authors : Zhang L; Institute of Clinical Pharmacology, Peking University First Hospital, Beijing 100191, China.; Wei MJ

Subjects: Cytochrome P-450 CYP1A2 Inhibitors* ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/drug effects ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/enzymology

  • Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2008 Dec; Vol. 29 (12), pp. 1507-14.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited

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Academic Journal

Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing.

  • Authors : Tilleman L; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.; Rubben K

Subjects: Nanopore Sequencing*; Humans ; Haplotypes

  • Source: Scientific reports [Sci Rep] 2022 Oct 22; Vol. 12 (1), pp. 17734. Date of Electronic Publication: 2022 Oct 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes.

  • Authors : Liu YT; Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.; Hao K

Subjects: Cytochrome P-450 CYP1A2 Inhibitors*; Benzoflavones/Benzoflavones/Benzoflavones/*pharmacology ; Microsomes, Liver/Microsomes, Liver/Microsomes, Liver/*metabolism

  • Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2006 Sep; Vol. 27 (9), pp. 1253-8.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited

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Academic Journal

Induction of liver cytochrome P450 1A2 expression by flutamide in rats.

  • Authors : Wang HX; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200032, China.; Liu X

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*biosynthesis ; Flutamide/Flutamide/Flutamide/*toxicity ; Liver/Liver/Liver/*enzymology

  • Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2005 Nov; Vol. 26 (11), pp. 1382-6.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited

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Academic Journal

A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion.

  • Authors : Schurink IJ; Division of Hepatopancreatobiliary Surgery, Department of Surgery, Erasmus MC Transplant Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; de Haan JE

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*genetics ; Liver/Liver/Liver/*physiology ; Liver Transplantation/Liver Transplantation/Liver Transplantation/*methods

  • Source: Scientific reports [Sci Rep] 2021 Dec 06; Vol. 11 (1), pp. 23444. Date of Electronic Publication: 2021 Dec 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Heterologous expression of high-activity cytochrome P450 in mammalian cells.

  • Authors : Kumondai M; Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba Aramaki, Aoba-ku, Sendai, 980-8578, Japan.; Hishinuma E

Subjects: Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*genetics ; Genetic Engineering/Genetic Engineering/Genetic Engineering/*methods ; Recombinant Proteins/Recombinant Proteins/Recombinant Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14193. Date of Electronic Publication: 2020 Aug 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

A novel naphthalimide that selectively targets breast cancer via the arylhydrocarbon receptor pathway.

  • Authors : Gilbert J; Experimental Therapeutics Group, Department of Medical Oncology, Calvary Mater Newcastle Hospital, Edith Street, Waratah, NSW, 2298, Australia.; De Iuliis GN

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Naphthalimides/Naphthalimides/Naphthalimides/*pharmacology ; Receptors, Aryl Hydrocarbon/Receptors, Aryl Hydrocarbon/Receptors, Aryl Hydrocarbon/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Aug 19; Vol. 10 (1), pp. 13978. Date of Electronic Publication: 2020 Aug 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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