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SomaLogic proteomics reveals new biomarkers and provides mechanistic, clinical insights into Acetyl coA Carboxylase (ACC) inhibition in Non-alcoholic Steatohepatitis (NASH).

• Authors : Sivakumar P; Translational Clinical Sciences, Pfizer Research and Development, 500 Arcola Road, Collegeville, PA, 19426, USA. .; Saul M

Subjects: Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/drug therapy ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/diagnosis ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism

• Source: Scientific reports [Sci Rep] 2024 Jul 24; Vol. 14 (1), pp. 17072. Date of Electronic Publication: 2024 Jul 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities

• Authors : Chieh-Ting Fang; Hsiao-Hui Kuo; Oyundari Amartuvshin

Subjects: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282; Cytology

• Source: Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)

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Inhibition of acetyl-CoA carboxylase by spirotetramat causes growth arrest and lipid depletion in nematodes.

• Authors : Gutbrod P; INRES, Molecular Phytomedicine, University of Bonn, Bonn, Germany.; IMBIO, Molecular Physiology and Biotechnology of Plants, University of Bonn, Bonn, Germany.

Subjects: Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*genetics ; Antinematodal Agents/Antinematodal Agents/Antinematodal Agents/*pharmacology ; Aza Compounds/Aza Compounds/Aza Compounds/*pharmacology

• Source: Scientific reports [Sci Rep] 2020 Jul 29; Vol. 10 (1), pp. 12710. Date of Electronic Publication: 2020 Jul 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Biochemical and structural characterization of quizalofop-resistant wheat acetyl-CoA carboxylase.

• Authors : Bough R; Department of Agricultural Biology, Colorado State University, Fort Collins, CO, 80523, USA.; Dayan FE

Subjects: Amino Acid Substitution*; Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*chemistry ; Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*genetics

• Source: Scientific reports [Sci Rep] 2022 Jan 13; Vol. 12 (1), pp. 679. Date of Electronic Publication: 2022 Jan 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Silencing acetyl-CoA carboxylase A and sterol regulatory element-binding protein 1 genes through RNAi reduce serum and egg cholesterol in chicken.

• Authors : Prasad AR; ICAR-Directorate of Poultry Research, Rajendranagar, Hyderabad, India.; Bhattacharya TK

Subjects: Eggs*; Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*genetics ; Chickens/Chickens/Chickens/*genetics

• Source: Scientific reports [Sci Rep] 2022 Jan 24; Vol. 12 (1), pp. 1191. Date of Electronic Publication: 2022 Jan 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.

• Authors : Wei J; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.; Tong L

Subjects: Protein Multimerization*; Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*chemistry ; Saccharomyces cerevisiae/Saccharomyces cerevisiae/Saccharomyces cerevisiae/*enzymology

• Source: Nature [Nature] 2015 Oct 29; Vol. 526 (7575), pp. 723-7. Date of Electronic Publication: 2015 Oct 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Inhibition of acetyl-CoA carboxylase by spirotetramat causes growth arrest and lipid depletion in nematodes

• Authors : Abdelnaser Elashry; Florian M. W. Grundler; Jürgen Benting

Subjects: 0106 biological sciences; 0301 basic medicine; lcsh:Medicine

• Source: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)Scientific ReportsScientific reports, vol 10, iss 1

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BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.

• Authors : Magnard C; Laboratoire de Génétique, CNRS UMR 5641, Université Claude Bernard Lyon I, Faculté de Médecine Rockefeller, 8 Avenue Rockefeller, 69373 Lyon cedex 08, France.; Bachelier R

Subjects: Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/Acetyl-CoA Carboxylase/*chemistry ; BRCA1 Protein/BRCA1 Protein/BRCA1 Protein/*chemistry; 3T3 Cells

• Source: Oncogene [Oncogene] 2002 Oct 03; Vol. 21 (44), pp. 6729-39.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium:

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Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5+ intestinal stem cell function

• Authors : Li, S.; Lu, C.-W.; Diem, E.C.

• Source: ISSN: 2041-1723.

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Docking of acetyl-CoA carboxylase to the plastid envelope membrane attenuates fatty acid production in plants

• Authors : Ye, Yajin; Nikovics, Krisztina; To, Alexandra ...

Subjects: [SDV.BBM]Life Sciences [q-bio]/Biochemistry; Molecular Biology

• Source: ISSN: 2041-1723.

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