نتائج البحث

Targeting NAD Metabolism: Rational Design, Synthesis and In Vitro Evaluation of NAMPT/PARP1 Dual-Target Inhibitors as Anti-Breast Cancer Agents.

• Authors : Li, Yingpeng^1,2 (AUTHOR); Kong, Xianxiu^1,2 (AUTHOR); Chu, Xinhong^1,2 (AUTHOR)

Subjects: *POLY ADP ribose; *NAD (Coenzyme); *NICOTINAMIDE

• Source: Molecules. Jun2024, Vol. 29 Issue 12, p2836. 26p.

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Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes.

• Authors : Matteucci, Federica¹ (AUTHOR) ; Ferrati, Marta¹ (AUTHOR) ; Spinozzi, Eleonora¹ (AUTHOR)

• Source: Pharmaceuticals (14248247). Jun2024, Vol. 17 Issue 6, p739. 15p.

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Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems.

• Authors : Sauter, Roland¹ (AUTHOR) ; Sharma, Suraj² (AUTHOR) ; Heiland, Ines^1,3 (AUTHOR)

• Source: Biomolecules (2218-273X). May2024, Vol. 14 Issue 5, p602. 11p.

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Adaptation of a Commercial NAD + Quantification Kit to Assay the Base-Exchange Activity and Substrate Preferences of SARM1.

• Authors : Cirilli, Ilenia¹ (AUTHOR) ; Amici, Adolfo¹ (AUTHOR) ; Gilley, Jonathan² (AUTHOR)

Subjects: *ION exchange (Chemistry); *NAD (Coenzyme); *BINDING site assay

• Source: Molecules. Feb2024, Vol. 29 Issue 4, p847. 12p.

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Two-Photon-Excited FLIM of NAD(P)H and FAD—Metabolic Activity of Fibroblasts for the Diagnostics of Osteoimplant Survival.

• Authors : Lepekhina, Tatiana B.¹ (AUTHOR) ; Nikolaev, Viktor V.¹ (AUTHOR) ; Darvin, Maxim E.² (AUTHOR)

Subjects: *NAD (Coenzyme); *FIBROBLASTS; *SCANNING electron microscopes

• Source: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2257. 14p.

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A Simple, Fast, Sensitive LC-MS/MS Method to Quantify NAD(H) in Biological Samples: Plasma NAD(H) Measurement to Monitor Brain Pathophysiology.

• Authors : Ishima, Tamaki¹ (AUTHOR) ; Kimura, Natsuka¹ (AUTHOR) ; Kobayashi, Mizuki² (AUTHOR)

Subjects: *NAD (Coenzyme); *LIQUID chromatography-mass spectrometry; *PATHOLOGICAL physiology

• Source: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2325. 14p.

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A Molecular Perspective and Role of NAD + in Ovarian Aging.

• Authors : Ahmed, Mehboob^1,2,3 (AUTHOR) ; Riaz, Umair^1,2,3 (AUTHOR) ; Lv, Haimiao^1,2,3 (AUTHOR)

Subjects: *NAD (Coenzyme); *ALZHEIMER'S disease; *OVARIAN reserve

• Source: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 9, p4680. 26p.

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NAD-Driven Sirtuin Activation by Cordyceps sinensis Extract: Exploring the Adaptogenic Potential to Promote Skin Longevity.

• Authors : Di Lorenzo, Ritamaria¹ (AUTHOR) ; Falanga, Danila² (AUTHOR) ; Ricci, Lucia¹ (AUTHOR)

Subjects: *CORDYCEPS; *NAD (Coenzyme); *SIRTUINS

• Source: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4282. 20p.

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Supplementation of Nicotinic Acid and Its Derivatives Up-Regulates Cellular NAD + Level Rather than Nicotinamide Derivatives in Cultured Normal Human Epidermal Keratinocytes.

• Authors : Oyama, Takahiro^1,2 (AUTHOR) ; Yamamoto, Takumi¹ (AUTHOR) ; Kameda, Takeshi¹ (AUTHOR)

• Source: Life (2075-1729). Mar2024, Vol. 14 Issue 3, p413. 10p.

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The Role of NAD + and NAD + -Boosting Therapies in Inflammatory Response by IL-13.

• Authors : Pugel, Anton D.^1,2 (AUTHOR) ; Schoenfeld, Alyssa M.² (AUTHOR) ; Alsaifi, Sara Z.² (AUTHOR)

• Source: Pharmaceuticals (14248247). Feb2024, Vol. 17 Issue 2, p226. 14p.

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