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BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension.

• Authors : Awad, Keytam S.¹ (AUTHOR) ; Wang, Shuibang¹ (AUTHOR) ; Dougherty, Edward J.¹ (AUTHOR)

Subjects: *PULMONARY arterial hypertension; *VASCULAR remodeling; *PULMONARY artery

• Source: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 10, p5403. 20p.

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Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress.

• Authors : Pagel, Judith-Irina¹ ; Deindl, Elisabeth¹

Subjects: *DISEASE progression; *OXIDATIVE stress; *CELLULAR signal transduction

• Source: International Journal of Molecular Sciences. Oct2012, Vol. 13 Issue 10, p13104-13117. 14p. 1 Diagram.

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Tadalafil Nanoemulsion Mists for Treatment of Pediatric Pulmonary Hypertension via Nebulization

• Authors : Elbardisy, Bassant; Boraie, Nabila; Galal, Sally

Subjects: Article; ddc:615; Veröffentlichung der TU Braunschweig

• Source: Pharmaceutics : Special Issue Drug Delivery Systems for Asthma and Pulmonary Diseases 14 (2022) 12, 2717. - https://doi.org/10.3390/ pharmaceutics14122717 --

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Iron replacement therapy with oral ferric maltol: review of the evidence and expert opinion

• Authors : Schmidt, Carsten; Allen, Stephen; Kopyt, Nelson ...

Subjects: article; ScholarlyArticle; ddc:610

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Andrographolide Attenuates Established Pulmonary Hypertension via Rescue of Vascular Remodeling

• Authors : Dai You'ai; Xusheng Yang; Wei Wang

Subjects: MAPK/ERK pathway; Male; andrographolide

• Source: BiomoleculesBiomolecules; Volume 11; Issue 12; Pages: 1801Biomolecules, Vol 11, Iss 1801, p 1801 (2021)

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Epidemiology and Management of Chronic Thromboembolic Pulmonary Hypertension in Greece. Real-World Data from the Hellenic Pulmonary Hypertension Registry (HOPE)

• Authors : Eftychia Demerouti; Panagiotis Karyofyllis; Vassilios Voudris

Subjects: medicine.medical_specialty; medicine.medical_treatment; Population

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 10, Iss 4547, p 4547 (2021)Volume 10Issue 19

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Adenylate Kinase 4—A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways

• Authors : Magdalena Wujak; Christine Veith; Cheng-Yu Wu

Subjects: QH301-705.5; hypoxia; AK4

• Source: International Journal of Molecular SciencesVolume 22Issue 19International Journal of Molecular Sciences, Vol 22, Iss 10371, p 10371 (2021)

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Chitin-Derived AVR-48 Prevents Experimental Bronchopulmonary Dysplasia (BPD) and BPD-Associated Pulmonary Hypertension in Newborn Mice

• Authors : Varsha M. Prahaladan; Suchismita Acharya; Alison J. Carey

Subjects: medicine.medical_specialty; Neonatal intensive care unit; QH301-705.5

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 8547, p 8547 (2021)Volume 22Issue 16

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Peripheral Arterial Stiffness in Acute Pulmonary Embolism and Pulmonary Hypertension at Short-Term Follow-Up

• Authors : Cristiano Miotti; Francesco Fedele; Francesco Ciciarello

Subjects: medicine.medical_specialty; pulmonary embolism; Physical examination

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 10, Iss 3008, p 3008 (2021)Volume 10Issue 14

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The Value of Heart Rhythm Complexity in Identifying High-Risk Pulmonary Hypertension Patients

• Authors : Hsi-Pin Ma; Ping-Hung Kuo; Yen-Hung Lin

Subjects: medicine.medical_specialty; Science; QC1-999

• Source: EntropyEntropy, Vol 23, Iss 753, p 753 (2021)Volume 23Issue 6

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Cardiac Manifestations in a Group of Romanian Patients with Gaucher Disease Type 1 (a Monocentric Study)

• Authors : Camelia Alkhzouz; Mirela Crișan; Ioana Nașcu

Subjects: Medicine (General); medicine.medical_specialty; medicine.medical_treatment

• Source: DiagnosticsDiagnostics, Vol 11, Iss 989, p 989 (2021)Volume 11Issue 6

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The Impact of COVID-19 Pandemic on Children with Pulmonary Arterial Hypertension. Parental Anxiety and Attitudes. Follow-Up Data from the Polish Registry of Pulmonary Hypertension (BNP-PL)

• Authors : Jacek Kusa; Joanna Płużańska; Barbara Wójcicka-Urbańska

Subjects: psychosocial; Pediatrics; medicine.medical_specialty

• Source: Journal of Clinical MedicineVolume 10Issue 8Journal of Clinical Medicine, Vol 10, Iss 1640, p 1640 (2021)

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Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension

• Authors : Ariadne Malamitsi-Puchner; Aimilia Eirini Papathanasiou; Helen Christou

Subjects: 0301 basic medicine; Male; Glucose uptake

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 1435, p 1435 (2021)Volume 22Issue 3

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Soluble ST2 as a Biomarker for Early Complications in Patients with Chronic Thromboembolic Pulmonary Hypertension Treated with Balloon Pulmonary Angioplasty

• Authors : Arkadiusz Pietrasik; Janusz Kochman; Michał Piłka

Subjects: endocrine system; medicine.medical_specialty; medicine.drug_class

• Source: DiagnosticsVolume 11Issue 1Diagnostics, Vol 11, Iss 133, p 133 (2021)

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Evidence of Pulmonary Hypertension after SARS-CoV-2 Infection in Subjects without Previous Significant Cardiovascular Pathology

• Authors : Mariana Tudoran; Alexandra Enache; Adelina Raluca Marinescu

Subjects: Thorax; medicine.medical_specialty; Cardiovascular pathology

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 10, Iss 199, p 199 (2021)Volume 10Issue 2

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Delivery of Nitric Oxide in the Cardiovascular System: Implications for Clinical Diagnosis and Therapy

• Authors : Yubo Fan; Tianxiang Ma; Zhexi Zhang

Subjects: computational modeling; inhaled NO therapy; QH301-705.5

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 12166, p 12166 (2021)

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Right Ventricular Structure and Function in Young Adults Born Preterm at Very Low Birth Weight

• Authors : Chris Frampton; Richard W. Troughton; Charlotte Greer

Subjects: cardiovascular risk; medicine.medical_specialty; education.field_of_study

• Source: Journal of Clinical MedicineVolume 10Issue 21Journal of Clinical Medicine, Vol 10, Iss 4864, p 4864 (2021)

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Impact of Three Different Algorithms for the Screening of SSc-PAH and Comparison with the Decisions of a Multidisciplinary Team

• Authors : Vincent Sobanski; Stéphane Jouneau; Nicolas Belhomme ...

Subjects: Right heart catheterization; Medicine (General); Longitudinal study

• Source: DiagnosticsDiagnostics, 2021, 11 (10), pp.1738. ⟨10.3390/diagnostics11101738⟩Diagnostics, MDPI, 2021, 11 (10), pp.1738.

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Differences between Acute Exacerbations of Idiopathic Pulmonary Fibrosis and Other Interstitial Lung Diseases

• Authors : Sara Conti; Stefania Cerri; Ada Vancheri ...

Subjects: Medicine (General); medicine.medical_specialty; Exacerbation

• Source: DiagnosticsDiagnostics, Vol 11, Iss 1623, p 1623 (2021)Volume 11Issue 9

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Interleukin-1β in Multifactorial Hypertension: Inflammation, Vascular Smooth Muscle Cell and Extracellular Matrix Remodeling, and Non-Coding RNA Regulation

• Authors : Hongyu Qiu; Elaina Melton

Subjects: Gestational hypertension; Vascular smooth muscle; hypertension

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 8639, p 8639 (2021)

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Current Modulation of Guanylate Cyclase Pathway Activity—Mechanism and Clinical Implications

• Authors : Alicja Nowaczyk; Grzegorz Grześk

Subjects: chronic heart failure (CHF); Pharmaceutical Science; Organic chemistry

• Source: MoleculesMolecules, Vol 26, Iss 3418, p 3418 (2021)

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Right Ventricle Remodeling Metabolic Signature in Experimental Pulmonary Hypertension Models of Chronic Hypoxia and Monocrotaline Exposure

• Authors : Laurent Savale; Jérôme Le Pavec; Francois Haddad ...

Subjects: 0301 basic medicine; Purine; Male

• Source: CellsCells, 2021, 10 (6), pp.1559. ⟨10.3390/cells10061559⟩Cells, Vol 10, Iss 1559, p 1559 (2021)Volume 10Issue 6

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A Multidisciplinary Approach to Evaluate the Presence of Hepatic and Cardiac Abnormalities in Patients with Post-Acute COVID-19 Syndrome—A Pilot Study

• Authors : Ioan Sporea; Cristina Tudoran; Roxana Sirli

Subjects: medicine.medical_specialty; Diastole; Disease

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 10, Iss 2507, p 2507 (2021)Volume 10Issue 11

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The Biological Bases of Group 2 Pulmonary Hypertension

• Authors : Paula Navas-Tejedor; Teresa Mombiela; Francisco Fernández-Avilés

Subjects: Epigenomics; Candidate gene; Hypertension, Pulmonary

• Source: International Journal of Molecular Sciences

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Prognostic Value of the Echocardiographic Probability of Pulmonary Hypertension in Patients with Acute Decompensated Heart Failure

• Authors : Philippe Musso; Jérôme Stirnemann; Nicolas Garin

Subjects: medicine.medical_specialty; Multivariate analysis; Acute decompensated heart failure

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 8, Iss 10, p 1684 (2019)Volume 8Issue 10

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Oxidative Stress, Kinase Activity and Inflammatory Implications in Right Ventricular Hypertrophy and Heart Failure under Hypobaric Hypoxia

• Authors : Samia El Alam; Patricia Siques; Eduardo Pena

Subjects: 0301 basic medicine; heart failure; Inflammation

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 21, Iss 6421, p 6421 (2020)

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Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries

• Authors : Davor Skofic Maurer; Diana Zabini; Chandran Nagaraj

Subjects: TMEM16A; Endothelial Cells; Ano1

• Source: CellsCells, Vol 9, Iss 1984, p 1984 (2020)

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AMPK and the Need to Breathe and Feed: What’s the Matter with Oxygen?

• Authors : A. Mark Evans; D. Grahame Hardie

Subjects: 0301 basic medicine; AMPK; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

• Source: International Journal of Molecular SciencesEvans, M & Hardie, D G 2020, ' AMPK and the need to breathe and feed: what’s the matter with oxygen? ', International Journal of Molecular Sciences,

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RNA Signaling in Pulmonary Arterial Hypertension—A Double-Stranded Sword

• Authors : Helena A Turton; Laszlo Farkas; A. A. Roger Thompson

Subjects: Endosome; vascular remodeling; Down-Regulation

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 21, Iss 3124, p 3124 (2020)

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Impaired Right and Left Ventricular Longitudinal Function in Patients with Fibrotic Interstitial Lung Diseases

• Authors : Ciro Santoro; Alessandro Sanduzzi; Agostino Buonauro ...

Subjects: medicine.medical_specialty; Population; lcsh:Medicine

• Source: Journal of Clinical MedicineJournal of Clinical Medicine, Vol 9, Iss 2, p 587 (2020)Volume 9Issue 2

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Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Fetal Pulmonary Circulation: An Experimental Study in Fetal Lambs

• Authors : Dyuti Sharma; Estelle Aubry; Thavarak Ouk

Subjects: Pulmonary Circulation; Sheep; Docosahexaenoic Acids

• Source: NutrientsNutrients, Vol 9, Iss 7, p 761 (2017)

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Adenylate Kinase 4-A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways.

• Authors : Wujak M; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Excellence Cluster Cardio-Pulmonary Institute (CPI), Justus-Liebig University, 35392 Giessen, Germany.; Department of Medicinal Chemistry, Collegium Medicum in Bydgoszcz, Faculty of Pharmacy, Nicolaus Copernicus University in Toruń, 85-089 Bydgoszcz, Poland.

Subjects: Cell Proliferation* ; Signal Transduction*; Adenylate Kinase/Adenylate Kinase/Adenylate Kinase/*metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 26; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Pulmonary Arterial Hypertension Due to NPR-C Mutation: A Novel Paradigm for Normal and Pathologic Remodeling?

• Authors : Egom EE; St Martha's Regional Hospital, Dalhousie University, Antigonish, B2G 2G7 NS, Canada. .

Subjects: Mutation* ; Signal Transduction*; Familial Primary Pulmonary Hypertension/Familial Primary Pulmonary Hypertension/Familial Primary Pulmonary Hypertension/*genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2019 Jun 22; Vol. 20 (12). Date of Electronic Publication: 2019 Jun 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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New Insights into Pulmonary Hypertension: A Role for Connexin-Mediated Signalling.

• Authors : Htet M; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA.; Nally JE

Subjects: Signal Transduction*; Connexins/Connexins/Connexins/*metabolism ; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 29; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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The Role of JAK/STAT Molecular Pathway in Vascular Remodeling Associated with Pulmonary Hypertension.

• Authors : Roger I; CIBERES, Health Institute Carlos III, 28029 Madrid, Spain.; Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.

Subjects: Signal Transduction* ; Vascular Remodeling*; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*physiopathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 May 07; Vol. 22 (9). Date of Electronic Publication: 2021 May 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention.

• Authors : Sanada TJ; Amsterdam UMC, Department of Pulmonology, Amsterdam Cardiovascular Sciences, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Sun XQ

Subjects: Signal Transduction*; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*metabolism ; Smad Proteins/Smad Proteins/Smad Proteins/*metabolism

• Source: Cells [Cells] 2021 Jan 06; Vol. 10 (1). Date of Electronic Publication: 2021 Jan 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Systematic Elucidation of the Mechanism of Genistein against Pulmonary Hypertension via Network Pharmacology Approach.

• Authors : Chen Y; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.; Chen D

Subjects: Antihypertensive Agents*/Antihypertensive Agents*/Antihypertensive Agents*/chemistry ; Antihypertensive Agents*/Antihypertensive Agents*/Antihypertensive Agents*/pharmacology ; Genistein*/Genistein*/Genistein*/chemistry

• Source: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 07; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms.

• Authors : Miao Q; Institute of Materia Medica, Fourth Military Medical University, Xi'an 710032, China.; Shi XP

Subjects: Glucosides/Glucosides/Glucosides/*pharmacology ; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*drug therapy ; Hypoxia/Hypoxia/Hypoxia/*drug therapy

• Source: International journal of molecular sciences [Int J Mol Sci] 2012; Vol. 13 (6), pp. 7776-7787. Date of Electronic Publication: 2012 Jun 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Print-Electronic Cited Medium:

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