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Massive tramadol ingestion resulting in fatal brain injury – a pharmacokinetic study with discussion on the involved mechanisms of toxicity

Authors : Alicja Puszkiel; Isabelle Malissin; Salvatore Cisternino

Subjects: Adult; Genotype; General Medicine

Source: Clinical Toxicology. 60:1059-1062

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Metabolism of gartanin in liver microsomes and its modulating effects on cytochrome P450s

Authors : Tao, Jia; Ai, Hao

Subjects: Pharmacology; Xanthones; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 52:335-345

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Exploring the Kinh Vietnamese genomic database for the polymorphisms of the P450 genes towards precision public health

Authors : Diep Thi, Hoang; Tran Van, Hiep; Thao, Thi Phuong Nguyen

Subjects: Aging; Physiology; Epidemiology

Source: Annals of Human Biology. 49:152-155

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Spectroscopic observations of β-eudesmol binding to human cytochrome P450 isoforms 3A4 and 1A2, but not to isoforms 2C9, 2C19, and 2D6

Authors : Dawid, Krenc; Kesara, Na-Bangchang

Subjects: Pharmacology; Spectrum Analysis; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 52:199-208

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Metabolic activation of zolmitriptan mediated by CYP2D6

Authors : Ying Peng; Chen Sun; Jiang Zheng

Subjects: Quinidine; Health, Toxicology and Mutagenesis; Pharmacology

Source: Xenobiotica. 51:1292-1302

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Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Authors : Juri Arima; Yurina Michihiro; Toshiro Niwa

Subjects: Fluphenazine; Arginine; Dopamine

Source: Xenobiotica. 51:1229-1235

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Effect of naringenin on the pharmacokinetics of metoprolol succinate in rats

Authors : Surya Sandeep Mullapudi; Yamini Gullapalli; Sridhar Vemulapalli

Subjects: Male; Naringenin; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 51:926-932

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Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6

Authors : Norie Murayama; Shotaro Uehara; Hiroshi Yamazaki

Subjects: Adult; Male; Drug

Source: Xenobiotica. 49:1323-1331

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Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen

Authors : Hans Gelderblom; Vincent O. Dezentjé; Jesse J. Swen

Subjects: Oncology; medicine.medical_specialty; CYP2D6

Source: Expert Review of Clinical Pharmacology, 12(6), 523-536

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The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

Authors : Hong-Ying Chen; Yu-Jie Zhang; Xiao-yan Yang

Subjects: Male; Berberine; Cytochrome P-450 CYP2C9 Inhibitors

Source: Drug Design, Development and Therapy

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فلترة النتائج

Massive tramadol ingestion resulting in fatal brain injury – a pharmacokinetic study with discussion on the involved mechanisms of toxicity

Metabolism of gartanin in liver microsomes and its modulating effects on cytochrome P450s

Exploring the Kinh Vietnamese genomic database for the polymorphisms of the P450 genes towards precision public health

Spectroscopic observations of β-eudesmol binding to human cytochrome P450 isoforms 3A4 and 1A2, but not to isoforms 2C9, 2C19, and 2D6

Metabolic activation of zolmitriptan mediated by CYP2D6

Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Effect of naringenin on the pharmacokinetics of metoprolol succinate in rats

Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6

Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen

The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

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