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Academic Journal

An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys.

  • Authors : Krausz KW; Laboratory of Molecular Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Goldfarb I

Subjects: Antibody Specificity* ; Aryl Hydrocarbon Hydroxylases* ; Cytochrome P-450 Enzyme Inhibitors*

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2000 Jun; Vol. 30 (6), pp. 619-25.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions.

  • Authors : Lewis DF; School of Biomedical and Life Sciences, University of Surrey, Guildford GU2 7XH, UK. ; Lake BG

Subjects: Aryl Hydrocarbon Hydroxylases*; Coumarins/Coumarins/Coumarins/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2002 Jul; Vol. 32 (7), pp. 547-61.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Hydroxylation of tanshinone IIa in human liver microsomes is specifically catalysed by cytochrome P4502A6.

  • Authors : Liu HX; Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.; Hu Y

Subjects: Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*metabolism ; Drugs, Chinese Herbal/Drugs, Chinese Herbal/Drugs, Chinese Herbal/*metabolism ; Microsomes, Liver/Microsomes, Liver/Microsomes, Liver/*enzymology

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2009 May; Vol. 39 (5), pp. 382-90.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.

  • Authors : Bretillon L; Eye and Nutrition Research Group, UMR 1129 FLAVIC, INRA, ENESAD, University of Burgundy, Dijon, France, and Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden. ; Diczfalusy U

Subjects: Neurons/Neurons/Neurons/*enzymology ; Retina/Retina/Retina/*enzymology ; Steroid Hydroxylases/Steroid Hydroxylases/Steroid Hydroxylases/*metabolism

  • Source: Current eye research [Curr Eye Res] 2007 Apr; Vol. 32 (4), pp. 361-6.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8104312 Publication Model: Print Cited Medium:

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Academic Journal

Decreased PXR and CAR inhibit transporter and CYP mRNA Levels in the liver and intestine of mice with collagen-induced arthritis.

  • Authors : Kawase A; Faculty of Pharmaceutical Sciences, Kinki University, Osaka, Japan.; Yoshida I

Subjects: Arthritis, Experimental/Arthritis, Experimental/Arthritis, Experimental/*metabolism ; Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*biosynthesis ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*biosynthesis

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2007 Apr; Vol. 37 (4), pp. 366-74.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung.

  • Authors : Qin G; Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China.; Meng Z

Subjects: Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*metabolism ; Cytochrome P-450 CYP2B1/Cytochrome P-450 CYP2B1/Cytochrome P-450 CYP2B1/*metabolism ; Cytochrome P-450 CYP2E1/Cytochrome P-450 CYP2E1/Cytochrome P-450 CYP2E1/*metabolism

  • Source: Inhalation toxicology [Inhal Toxicol] 2006 Jul; Vol. 18 (8), pp. 581-8.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8910739 Publication Model: Print Cited Medium:

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Academic Journal

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.

  • Authors : Lewis DF; Molecular Toxicology Group, School of Biological Sciences, University of Surrey, Guildford, UK.; Dickins M

Subjects: Aryl Hydrocarbon Hydroxylases* ; Models, Molecular* ; Steroid 16-alpha-Hydroxylase*

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1998 Mar; Vol. 28 (3), pp. 235-68.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Characterization of mixtures of recombinant human cytochrome p450s as a screening model for metabolic stability in drug discovery.

  • Authors : Hagen N; Department of Analytical and Pharmaceutical Chemistry, The Royal Danish School of Pharmacy, DK-2100 Copenhagen, Denmark. ; Olsen AK

Subjects: Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*chemistry ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*chemistry ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2002 Sep; Vol. 32 (9), pp. 749-59.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Different expression of hepatic and renal cytochrome P450s between the streptozotocin-induced diabetic mouse and rat.

  • Authors : Sakuma T; Department of Toxicology, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan. ; Honma R

Subjects: Anti-Bacterial Agents* ; Aryl Hydrocarbon Hydroxylases* ; Steroid Hydroxylases*

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2001 Apr; Vol. 31 (4), pp. 223-37.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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Academic Journal

Evidence for propofol hydroxylation by cytochrome P4502B11 in canine liver microsomes: breed and gender differences.

  • Authors : Hay Kraus BL; Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts, USA.; Greenblatt DJ

Subjects: Steroid Hydroxylases*; Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2000 Jun; Vol. 30 (6), pp. 575-88.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium:

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