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The alteration of drug metabolism enzymes and pharmacokinetic parameters in nonalcoholic fatty liver disease: current animal models and clinical practice.

• Authors : Zhu Y; Department of Pharmacy, Affiliated Hospital of Zunyi Medical University, Zunyi, China.; Chen L

Subjects: Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism; Animals ; Humans

• Source: Drug metabolism reviews [Drug Metab Rev] 2023 Aug; Vol. 55 (3), pp. 163-180. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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Aldehyde oxidase mediated drug metabolism: an underpredicted obstacle in drug discovery and development.

• Authors : Gajula SNR; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER)-Hyderabad, Balanagar, Telangana, India.; Nathani TN

Subjects: Aldehyde Oxidase*/Aldehyde Oxidase*/Aldehyde Oxidase*/metabolism ; Drug Discovery*; Humans

• Source: Drug metabolism reviews [Drug Metab Rev] 2022 Nov; Vol. 54 (4), pp. 427-448. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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A transcriptional regulatory network of HNF4α and HNF1α involved in human diseases and drug metabolism.

• Authors : Yang J; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.; Bai X

Subjects: Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/genetics ; Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/metabolism ; Liver*/Liver*/Liver*/metabolism

• Source: Drug metabolism reviews [Drug Metab Rev] 2022 Nov; Vol. 54 (4), pp. 361-385. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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Relationship between blood-brain barrier changes and drug metabolism under high-altitude hypoxia: obstacle or opportunity for drug transport?

• Authors : Liu G; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.; Bai X

Subjects: Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/metabolism ; Altitude Sickness*/Altitude Sickness*/Altitude Sickness*/metabolism; Humans

• Source: Drug metabolism reviews [Drug Metab Rev] 2023 Feb-May; Vol. 55 (1-2), pp. 107-125. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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The effects of fasting on drug metabolism

• Authors : Apotheek Veiligheid en Kwaliteit; UMC Utrecht; Lammers, Laureen A

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Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism.

• Authors : Stanley LA; Consultant in Investigative Toxicology, Linlithgow, UK.; School of Applied Sciences, Edinburgh Napier University, Edinburgh, UK.

Subjects: Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism ; Proteomics*; Cell Line

• Source: Drug metabolism reviews [Drug Metab Rev] 2022 Feb; Vol. 54 (1), pp. 46-62. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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Nonadditivity in human microsomal drug metabolism revealed in a study with coumarin 152, a polyspecific cytochrome P450 substrate.

• Authors : Dangi B; Department of Chemistry, Washington State University, Pullman, WA, USA.; Davydova NY

Subjects: Coumarins/Coumarins/Coumarins/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism ; Metabolic Clearance Rate/Metabolic Clearance Rate/Metabolic Clearance Rate/*physiology

• Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 Dec; Vol. 50 (12), pp. 1393-1405. Date of Electronic Publication: 2020 Jul 26.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited

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Advances in the study of drug metabolism - symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX).

• Authors : Russell LE; Department of Physiology and Pharmacology, University of Western Ontario, London, ON, Canada.; Schleiff MA

Subjects: Computational Biology* ; Drug Discovery* ; Xenobiotics*

• Source: Drug metabolism reviews [Drug Metab Rev] 2020 Aug; Vol. 52 (3), pp. 395-407. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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Circadian clock-controlled drug metabolism and transport.

• Authors : Zhao M; Research Center for Biopharmaceutics and Pharmacokinetics, College of Pharmacy, Jinan University, Guangzhou, China.; Xing H

Subjects: Circadian Clocks* ; Inactivation, Metabolic*; Circadian Rhythm

• Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 May; Vol. 50 (5), pp. 495-505. Date of Electronic Publication: 2019 Oct 01.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited

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Moonlighting in drug metabolism.

• Authors : Board PG; John Curtin School of Medical Research, ANU College of Health and Medicine, The Australian National University, Canberra, ACT, Australia.; Anders MW

Subjects: Biotransformation*; Humans ; Oxidation-Reduction

• Source: Drug metabolism reviews [Drug Metab Rev] 2021 Feb; Vol. 53 (1), pp. 76-99. Date of Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited

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