نتائج البحث

A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD

• Authors : Lee, Davin; Jeong, Hae Chan; Kim, Seung Yeol ...

• Source: Molecules and Cells ; volume 47, issue 1, page 100005 ; ISSN 1016-8478

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A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis

• Authors : Massachusetts Institute of Technology. Department of Biology; McGovern Institute for Brain Research at MIT; Corrionero Saiz, Ana

Subjects: Article; http://purl.org/eprint/type/JournalArticle

• Source: Anna Corrionero

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Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice

• Authors : Toshihide Takeuchi; Kazuhiro Maeta; Xin Ding

Subjects: Drug Discovery; Molecular Medicine

• Source: Molecular Therapy - Nucleic Acids. 31:353-366

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Molecular determinants and modifiers of the toxicity, condensate dynamics, and droplet morphology of the ALS/FTD-associated protein Matrin-3

• Authors : Jackrel, Meredith

• Source: Biophysical Journal ; volume 122, issue 3, page 442a-443a ; ISSN 0006-3495

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The endolysosomal pathway and ALS/FTD

• Authors : Todd, Tiffany W.; Shao, Wei; Zhang, Yong-jie ...

• Source: Trends in Neurosciences ; volume 46, issue 12, page 1025-1041 ; ISSN 0166-2236

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Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD

• Authors : Afroz, Tariq; Chevalier, Elodie; Audrain, Mickael

• Source: Neurobiology of Disease ; volume 179, page 106050 ; ISSN 0969-9961

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C9orf72 poly(PR) aggregation in nucleus induces ALS/FTD-related neurodegeneration in cynomolgus monkeys

• Authors : Xu, Lizhu; Wang, Dan; Zhao, Lu ...

• Source: Neurobiology of Disease ; volume 184, page 106197 ; ISSN 0969-9961

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Abstract 1332: Histone Phosphorylation in ALS/FTD: New Opportunities in Neurodegenerative Disease

• Authors : Torrente, Mariana; Cobos, Samantha; Bennett, Seth

• Source: Journal of Biological Chemistry ; volume 299, issue 3, page 104003 ; ISSN 0021-9258

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Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

• Authors : Czuppa, Mareike; Dhingra, Ashutosh; Zhou, Qihui

Subjects: info:eu-repo/classification/ddc

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Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons

• Authors : Arredondo, Cristian; Cefaliello, Carolina; Dyrda, Agnieszka

• Source: Neuron ; volume 110, issue 10, page 1656-1670.e12 ; ISSN 0896-6273

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