نتائج البحث

Stimulating intestinal GIP release reduces food intake and body weight in mice. ...

• Authors : Lewis, Jo E; Nuzzaci, Danae; James-Okoro, Paula-Peace

Subjects: Diabetes; Enteroendocrine cells; Feeding behaviour

تفاصيل العنوان

Fasting and post prandial pancreatic and enteroendocrine hormone levels in obese and non-obese participants. ...

• Authors : Bannon, Christopher A; Meek, Claire L; Reimann, Frank

Subjects: BMI; GIP; GLP-1

تفاصيل العنوان

Relationship between inflammation and metabolic regulation of energy expenditure by GLP-1 in critically ill children.

• Authors : Zaher, Sara; Branco, Ricardo; Meyer, Rosan

Subjects: Critical illness; Energy expenditure; GLP-1

تفاصيل العنوان

Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy

• Authors : Blouet, Clemence; Roth, Emma; Benoit, Simon

Subjects: CCK; Combinatorial therapy; GLP-1

تفاصيل العنوان

Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery.

• Authors : Larraufie, Pierre; Roberts, Geoffrey P; McGavigan, Anne K

Subjects: GLP-1; bariatric surgery; enteroendocrine cells

تفاصيل العنوان

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

• Authors : Kuhre, Rune E; Wewer Albrechtsen, Nicolai J; Larsen, Olav

Subjects: Bile-acids; GLP-1; Insulin

تفاصيل العنوان

Gastrectomy with Roux-en-Y reconstruction as a lean model of bariatric surgery.

• Authors : Roberts, Geoffrey P; Kay, Richard G; Howard, James

Subjects: Bariatric surgery; Roux-en-Y gastric bypass; gastrectomy

تفاصيل العنوان

Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene

• Authors : Yuxiao Liu; Xiaozhen Dai; Xiao-Lin Liu

Subjects: Male; 0301 basic medicine; HFD, high-fat diet

• Source: Cellular and Molecular Gastroenterology and HepatologyCellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)

تفاصيل العنوان

High fat diet impairs the function of glucagon-like peptide-1 producing L-cells.

• Authors : Richards, Paul; Pais, Ramona; Habib, Abdella M

Subjects: Enteroendocrine; GLP-1; High fat diet

تفاصيل العنوان

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells.

• Authors : Hodge, Daryl; Glass, Leslie L; Diakogiannaki, Eleftheria

Subjects: GLP-1; GPR119; Incretin

تفاصيل العنوان

Curdlan intake changes gut microbial composition, short-chain fatty acid production, and bile acid transformation in mice

• Authors : Ryuji Ohue-Kitano; Keita Watanabe; Mayu Yamano

Subjects: HFD, high-fat diet; QH301-705.5; medicine.drug_class

• Source: Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101095-(2021)Biochemistry and Biophysics Reports

تفاصيل العنوان

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

• Authors : Thomas Laeger; Louise Fritsche; Christian Baumeier

Subjects: 0301 basic medicine; Male; HFD, high-fat diet

• Source: Molecular MetabolismMol. Metab. 6, 1254-1263 (2017)Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

تفاصيل العنوان

Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery

• Authors : Charles R. Flynn; Vance L. Albaugh; Naji N. Abumrad

Subjects: 0301 basic medicine; Bariatric Surgery; Receptors, Cytoplasmic and Nuclear

• Source: Cellular and Molecular Gastroenterology and HepatologyCellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 2, Pp 235-246 (2019)

تفاصيل العنوان

Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

• Authors : Anup Bobhate; Arjan Narbad; Udo Wegmann

Subjects: G-KRB, glucose-Krebs ringer buffer; 0301 basic medicine; DPP4, Dipeptidyl peptidase 4

• Source: Molecular Metabolism, Vol 5, Iss 8, Pp 725-730 (2016)Molecular Metabolism

تفاصيل العنوان

Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes

• Authors : Christin L. Hertz; Rune Viig Overgaard; Daniel J. Drucker

Subjects: Male; obesity; Medicine (General)

• Source: Cell Reports Medicine, Vol 2, Iss 9, Pp 100387-(2021)Cell Reports Medicine

تفاصيل العنوان

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

• Authors : Maria Lucey; Stavroula Bitsi; Alejandra Tomas ...

Subjects: Blood Glucose; Male; 0301 basic medicine

• Source: Molecular Metabolism, Vol 51, Iss, Pp 101242-(2021)Molecular Metabolism

تفاصيل العنوان

Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice

• Authors : James L. Trevaskis; Anthony Celeste; Michelle L. Boland

Subjects: Liver Cirrhosis; Male; 0301 basic medicine

• Source: Molecular Metabolism, Vol 6, Iss 11, Pp 1360-1370 (2017)Molecular Metabolism

تفاصيل العنوان

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

• Authors : Andreas Ludwig; Xiemin Cao; Alexandra Mighiu

Subjects: Male; 0301 basic medicine; Chronotropic

• Source: Molecular MetabolismMolecular Metabolism, Vol 6, Iss 11, Pp 1339-1349 (2017)

تفاصيل العنوان

The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

• Authors : Christina N. Heiss; Randy J. Seeley; Ying Shiuan Lee

Subjects: Leptin; Male; 0301 basic medicine

• Source: Heiss, C N, Mannerås-Holm, L, Lee, Y S, Serrano-Lobo, J, Håkansson Gladh, A, Seeley, R J, Drucker, D J, Bäckhed, F & Olofsson, L E 2021, ' The gut microbiota regulates hypothalamic inflammation and

تفاصيل العنوان

Once Blind, Now We See GLP-1 Molecular Action

• Authors : John P. Mayer; Richard D. DiMarchi; Matthias H. Tschöp

Subjects: 0301 basic medicine; Cognitive science; endocrine system

• Source: Cell Metab. 26, 289-291 (2017)

تفاصيل العنوان

Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy

• Authors : Emma Roth; James L. Trevaskis; Yashaswi Shrestha ...

Subjects: Male; 0301 basic medicine; Combinatorial therapy

• Source: Molecular Metabolism

تفاصيل العنوان

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

• Authors : Carmelle Cuizon; Mark Naples; Rianna Zhang

Subjects: lcsh:Internal medicine; Fasting dyslipidemia; Hepatic steatosis

• Source: Molecular MetabolismMolecular Metabolism, Vol 3, Iss 9, Pp 823-833 (2014)

تفاصيل العنوان

Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF-κB and MAPK pathways via GLP-1R

• Authors : Peng Xue; Yukun Li; Na Wang

Subjects: Male; 0301 basic medicine; Agonist

• Source: Biomedicine & Pharmacotherapy, Vol 130, Iss, Pp 110523-(2020)

تفاصيل العنوان

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4

• Authors : Sharon Kaufman; Nino Jejelava; Jean-Philippe Krieger

Subjects: 0301 basic medicine; lcsh:Internal medicine; medicine.medical_specialty

• Source: Molecular MetabolismMolecular Metabolism, 5 (7)Molecular Metabolism, Vol 5, Iss 7, Pp 552-565 (2016)

تفاصيل العنوان

Association of genetic variants of the incretin-related genes with quantitative traits and occurrence of type 2 diabetes in Japanese

• Authors : Katsumi Iizuka; Yukio Horikawa; Mayumi Enya

Subjects: LD, linkage disequilibrium; BMI, body mass index; GIPR, GIP receptor

• Source: Molecular Genetics and Metabolism ReportsMolecular Genetics and Metabolism Reports, Vol 1, Iss C, Pp 350-361 (2014)

تفاصيل العنوان

Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

• Authors : Tina Vilsbøll; Reidar Albrechtsen; Nicolai J. Wewer Albrechtsen

Subjects: 0301 basic medicine; Proteomics; medicine.medical_specialty

• Source: EBioMedicineEBioMedicine, Vol 7, Iss C, Pp 112-120 (2016)BASE-Bielefeld Academic Search Engine

تفاصيل العنوان

Retrospective analysis of safety and efficacy of liraglutide monotherapy and sulfonylurea-combination therapy in Japanese type 2 diabetes: Association of remaining β-cell function and achievement of HbA1c target one year after initiation

• Authors : Kenta Murotani; Yutaka Seino; Ryota Usui

Subjects: Male; Oncology; β-Cell function

• Source: Journal of Diabetes and its Complications. 29(8):1203-1210

تفاصيل العنوان

Downregulation of the GLP-1/CREB/adiponectin pathway is partially responsible for diabetes-induced dysregulated vascular tone and VSMC dysfunction

• Authors : Weimin Zhou; Weihang Lu; Xuan Qin

Subjects: Male; 0301 basic medicine; Vascular smooth muscle

• Source: Biomedicine & Pharmacotherapy, Vol 127, Iss, Pp 110218-(2020)

تفاصيل العنوان

Using Enteroendocrine Cell–Enriched Human Enteroids to Evaluate Responses to Gut Stimuli

• Authors : Nicholas C. Zachos

Subjects: VIL1, villin; Enteroendocrine cell; CMGF+, complete media with growth factors

• Source: Cellular and Molecular Gastroenterology and Hepatology

تفاصيل العنوان

Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

• Authors : Paul A. Dawson; Courtney B. Ferrebee

Subjects: HNF4α, hepatocyte nuclear factor 4 alpha; OATP, organic anion transporting polypeptide; PPAR, peroxisome proliferator-activated receptor

• Source: Acta Pharmaceutica Sinica. BActa Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)

تفاصيل العنوان

Mapping glucose-mediated gut-to-brain signalling pathways in humans

• Authors : Orsolya Kiss; John McLaughlin; Richard B. Jones

Subjects: Adult; Male; medicine.medical_specialty

• Source: Neuroimage

تفاصيل العنوان

Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in Type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-S)

• Authors : Isabel Muehlen-Bartmer; Robert E. Ratner; Paramesh Shamanna

Subjects: Blood Glucose; Male; Internationality

• Source: Journal of Diabetes and its Complications. 28(3):386-392

تفاصيل العنوان

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying

• Authors : Andrew V. Turnbull; Kryscilla Jian Zhang Yang; Jason J. Yuen

Subjects: Male; Indoles; Biochemistry

• Source: Journal of Lipid Research, Vol 53, Iss 11, Pp 2364-2379 (2012)Journal of Lipid Research

تفاصيل العنوان

Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease

• Authors : Simonetta Camandola; Mark P. Mattson

Subjects: Amyloid; Aging; medicine.medical_specialty

• Source: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813:965-973

تفاصيل العنوان

Health State Utilities Associated With Attributes of Weekly Injection Devices for Treatment of Type 2 Diabetes

• Authors : Katie D. Stewart; Louis S. Matza; Rosirene Paczkowski

Subjects: Male; Weekly injection; Time Factors

• Source: BMC Health Services ResearchBMC Health Services Research, Vol 17, Iss 1, Pp 1-10 (2017)

تفاصيل العنوان