نتائج البحث

Novel synthesis and evaluation of oligonucleotides containing (S)-5′-C-aminopropyl-modified thymidine analogs for RNase H-dependent antisense therapy

• Authors : Hiroki Hibino; Yujun Zhou; Yume Saito

Subjects: Antisense oligonucleotides; 5′-Aminopropyl; 2′-Aminoethoxy

• Source: Results in Chemistry, Vol 9, Iss , Pp 101648- (2024)

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Quantitative analysis of miRNAs using SplintR ligase-mediated ligation of complementary-pairing probes enhanced by RNase H (SPLICER)-qPCR

• Authors : Xinshu Qin; Xingyu Wang; Ke Xu

Subjects: MT: Oligonucleotides: Diagnostics and Biosensors; molecular diagnosis; miRNA quantification

• Source: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 241-255 (2023)

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Novel RNase H Inhibitors Blocking RNA-directed Strand Displacement DNA Synthesis by HIV-1 Reverse Transcriptase

• Authors : Martín-Alonso, Samar; Kang, Dongwei; Martínez Del Río, Javier ...

Subjects: Strand displacement; HIV; RNase H

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Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells

• Authors : Maxim S. Kupryushkin; Anton V. Filatov; Nadezhda L. Mironova

Subjects: antisense oligonucleotide gapmer; phosphoryl guanidine; gene silencing

• Source: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 211-226 (2022)

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The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry

• Authors : Terrazas, Montserrat; Genna, Vito; Portella, Guillem ...

Subjects: Physical origin; Chemical and biological consequences; CRISPR/Cas9

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Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer

• Authors : Jie Zheng; Anthony Hoang; Steve Tuske

Subjects: biology; Chemistry; SELEX

• Source: Current Research in Structural Biology, Vol 2, Iss, Pp 116-129 (2020)Current research in structural biology

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Preparation of Small RNAs Using Rolling Circle Transcription and Site-Specific RNA Disconnection

• Authors : Xingyu Wang; Can Li; Xiaomeng Gao

Subjects: biosynthesis; RNase H; RNA oligonucleotides

• Source: Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)

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The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry

• Authors : Rory Johnson; Roderic Guigó; Montserrat Terrazas ...

Subjects: Purine; DNA·RNA hybrids; RNase H

• Source: Recercat. Dipósit de la Recerca de CatalunyainstnameChemDipòsit Digital de la UBUniversidad de BarcelonaDigital.CSIC. Repositorio Institucional del CSIC

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Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors

• Authors : National Natural Science Foundation of China; Shandong Province; Ministerio de Ciencia e Innovación (España)

Subjects: Reverse transcriptase; AIDS; Drug design

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RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy

• Authors : Sara Bonato; Maurizio Moggio; Alice Zanolini ...

Subjects: Mitochondrial encephalomyopathy; Male; Ophthalmoplegia, Chronic Progressive External

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