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A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1

• Authors : Manoharan Rupavarshini; Subramani Karthikeyan; Sundaramoorthy Anandh

Subjects: Cytarabine – anticancer drug; Drug binding pocket; FRET

• Source: Results in Chemistry, Vol 5, Iss , Pp 100755- (2023)

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Precise nano-system-based drug delivery and synergistic therapy against androgen receptor-positive triple-negative breast cancer

• Authors : Fangyan Gao; Yueyao Wu; Runtian Wang

Subjects: Triple-negative breast cancer; Androgen receptor; Checkpoint kinase 1

• Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2685-2697 (2024)

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Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells

• Authors : Peralta-Sastre, A.; Manguan-García, Cristina; Luis, Alberto de

Subjects: artículo

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Checkpoint kinase 1 modulates sensitivity to chemotherapy in aneuploid cell lines

• Authors : Sánchez-Pérez, Isabel; Peralta-Sastre, A.; Manguan-García, Cristina

Subjects: póster de congreso

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Checkpoint kinase 1 is activated and promotes cell survival after exposure to sulphur mustard

• Authors : Jowsey, Paul; Blain, Peter G.

Subjects: B200 Pharmacology; Toxicology and Pharmacy

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A three-step synthesis from rebeccamycin of an efficient checkpoint kinase 1 inhibitor.

• Authors : Anizon, Fabrice; Golsteyn, Roy; Leonce, Stéphane ...

Subjects: Rebeccamycin; Staurosporine; Antitumor agents

• Source: ISSN: 0223-5234.

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Cell proliferation inhibitors and apoptosis promoters

• Authors : J. Alejandro Perez-Fidalgo

Subjects: Wee-1 inhibitors; Checkpoint kinase 1 inhibitor; p53 modulators

• Source: EJC Supplements, Vol 15, Iss , Pp 73-76 (2020)

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A Phase 2 study of prexasertib (LY2606368) in platinum resistant or refractory recurrent ovarian cancer

• Authors : Konstantinopoulos, Panagiotis A.; Lee, Jung-Min; Gao, Bo

Subjects: Science & Technology; Life Sciences & Biomedicine; Oncology

• Source: ISSN:0090-8258 ; ISSN:1095-6859 ; Gynecologic Oncology, vol. 167 (2), (213-225.

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Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways.

• Authors : Tian H; Department of Radiation Medicine, Lombardi Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road, N.W., Washington, DC 20007-2197, USA.; Faje AT

Subjects: Protein Kinases/Protein Kinases/Protein Kinases/*metabolism ; Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/*metabolism; 14-3-3 Proteins

• Source: Neoplasia (New York, N.Y.) [Neoplasia] 2002 Mar-Apr; Vol. 4 (2), pp. 171-80.Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print Cited Medium: Print

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Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism.

• Authors : Luo Y; Department 47S AP9A, Cancer Research, Pharmaceutical Products Division, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064, USA. ; Rockow-Magnone SK

Subjects: Apoptosis* ; Oxazines* ; Protein Kinase Inhibitors*

• Source: Neoplasia (New York, N.Y.) [Neoplasia] 2001 Sep-Oct; Vol. 3 (5), pp. 411-9.Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print Cited Medium: Print

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