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Academic Journal

Evaluation of factors affecting gastrointestinal absorption of a novel anticoagulant FX-93 for development of oral formulation.

  • Authors : Takemura S; Pharmaceutical Research and Technology Laboratories, Astellas Pharma Inc, Yaizu, Shizuoka 425-0072, Japan.; Kondo H

Subjects: Intestinal Absorption*; Amidines/Amidines/Amidines/*pharmacokinetics ; Anticoagulants/Anticoagulants/Anticoagulants/*pharmacokinetics

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2012 Jun; Vol. 101 (6), pp. 2134-42. Date of Electronic Publication: 2012 Mar 15.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

N-substituted bis-C-alkyloxadiazolones as dual effectors: efficient intermediates to amidoxines or amidines and prodrug candidates of potent antimalarials

Subjects: Bis-C-alkylamidine; Convenient route; N-substituted alkyloxadiazolone

  • Source: ISSN: 0960-894X ; Bioorganic and Medicinal Chemistry Letters ; https://hal.science/hal-00413778 ; Bioorganic and Medicinal Chemistry Letters, 2009, 19 (17), pp.5233-5236.

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Academic Journal

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability.

  • Authors : Schade D; Christian-Albrechts University of Kiel, Pharmaceutical Institute, Department of Pharmaceutical Chemistry, Kiel, 24118, Germany.; Kotthaus J

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacokinetics ; Guanidines/Guanidines/Guanidines/*pharmacokinetics ; Prodrugs/Prodrugs/Prodrugs/*pharmacokinetics

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2015 Sep; Vol. 104 (9), pp. 3208-19. Date of Electronic Publication: 2015 Jun 02.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Investigation of DNA-binding properties of organic molecules using quantitative structure-activity relationship (QSAR) models.

  • Authors : Verma RP; Department of Chemistry, Pomona College, 645 North College Avenue, Claremont, CA 91711, USA. ; Hansch C

Subjects: Quantitative Structure-Activity Relationship*; DNA/DNA/DNA/*metabolism ; Organic Chemicals/Organic Chemicals/Organic Chemicals/*metabolism

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2008 Jan; Vol. 97 (1), pp. 88-110.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Print

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Academic Journal

Physical stability and recrystallization kinetics of amorphous ibipinabant drug product by fourier transform raman spectroscopy.

  • Authors : Sinclair W; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Reeds Lane, Moreton, Merseyside CH46 1QW, UK. ; Leane M

Subjects: Crystallization*; Amidines/Amidines/Amidines/*chemistry ; Pyrazoles/Pyrazoles/Pyrazoles/*chemistry

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2011 Nov; Vol. 100 (11), pp. 4687-99. Date of Electronic Publication: 2011 Jun 16.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium:

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