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GSK126 an inhibitor of epigenetic regulator EZH2 suppresses cardiac fibrosis by regulating the EZH2-PAX6-CXCL10 pathway.

• Authors : Aziz, Shireen ; Yalan, Li; Raza, Muhammad Ahmer

Subjects: *HEART fibrosis; *CARDIAC hypertrophy; *HEART diseases

• Source: Biochemistry & Cell Biology. 2023, Vol. 101 Issue 1, p87-100. 14p.

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The impact of epigenetics on cardiovascular disease1.

• Authors : Prasher, Dimple¹; Greenway, Steven C.^1,2,3,4; Singh, Raja B.^1,4,5

Subjects: *EPIGENOMICS; *DNA methyltransferases; *CONGENITAL heart disease

• Source: Biochemistry & Cell Biology. Feb2020, Vol. 98 Issue 1, p12-22. 11p.

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Novel molecular therapeutic targets in cardiac fibrosis: a brief overview.

• Authors : Wang, Ryan¹; Lin, Justin^1,2; Bagchi, Rushita A.³

• Source: Canadian Journal of Physiology & Pharmacology. Apr2019, Vol. 97 Issue 4, p246-256. 11p. 2 Diagrams.

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Transcriptional regulation of endothelial-to-mesenchymal transition in cardiac fibrosis: role of myocardin-related transcription factor A and activating transcription factor 3.

• Authors : Sharma, Vibhuti¹; Saikia, Uma Nahar¹; Dogra, Nilambra²

• Source: Canadian Journal of Physiology & Pharmacology. 2017, Vol. 95 Issue 10, p1263-1270. 8p.

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A primer on current progress in cardiac fibrosis.

• Authors : Al Hattab, Danah^1,2; Czubryt, Michael P.^1,2

• Source: Canadian Journal of Physiology & Pharmacology. 2017, Vol. 95 Issue 10, p1091-1099. 9p.

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Brain natriuretic peptide appears to act locally as an antifibrotic factor in the heart.

• Authors : Ogawa, Yoshihiro; Tamura, Naohisa; Chusho, Hideki

• Source: Canadian Journal of Physiology & Pharmacology. Aug2001, Vol. 79 Issue 8, p723-729. 7p.

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miR-30a-5p inhibits the proliferation and collagen formation of cardiac fibroblasts in diabetic cardiomyopathy.

• Authors : Yang, Xiao-xu¹; Zhao, Zhen-yu¹

• Source: Canadian Journal of Physiology & Pharmacology. 2022, Vol. 100 Issue 2, p167-175. 9p.

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Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.

• Authors : Liu, Yun; Zhao, Jinsong; Lu, Meili

Subjects: TRETINOIN; HYPERGLYCEMIA; GESTATIONAL diabetes

• Source: Canadian Journal of Physiology & Pharmacology; 2020, Vol. 98 Issue 1, p6-14, 9p

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Polyethylene-glycol-coated gold nanoparticles improve cardiac function after myocardial infarction in mice.

• Authors : Tian, Aiju; Yang, Chengzhi; Zhu, Baoling

Subjects: GOLD nanoparticles; DRUG delivery systems; MYOCARDIAL infarction

• Source: Canadian Journal of Physiology & Pharmacology; 2018, Vol. 96 Issue 12, p1318-1327, 10p

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Gender-related differences in β-adrenergic receptor-mediated cardiac remodeling.

• Authors : Zhu, Baoling; Liu, Kai; Yang, Chengzhi

Subjects: VENTRICULAR remodeling; SEX differences (Biology); ADRENERGIC beta blockers

• Source: Canadian Journal of Physiology & Pharmacology; Dec2016, Vol. 94 Issue 12, p1349-1355, 7p

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