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  • 1-10 ل  201 نتائج ل ""Mechanistic Target of Rapamycin Complex 1""

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Publisher : biomed central
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Academic Journal

Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.

  • Authors : Huang KC; Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.

Subjects: Retinal Ganglion Cells*/Retinal Ganglion Cells*/Retinal Ganglion Cells*/pathology ; Retinal Ganglion Cells*/Retinal Ganglion Cells*/Retinal Ganglion Cells*/metabolism ; Autophagy*/Autophagy*/Autophagy*/physiology

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Oct 18; Vol. 12 (1), pp. 164. Date of Electronic Publication: 2024 Oct 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium:

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Academic Journal

TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts.

  • Authors : Yang B; Department of Cardiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.; Wang Z

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Mice, Knockout*

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 20; Vol. 22 (1), pp. 444. Date of Electronic Publication: 2024 Sep 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium:

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Academic Journal

Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses.

  • Authors : Honoré E; Department of Neurosciences, Center for Interdisciplinary Research on Brain and Learning (CIRCA) and Research Group on Neural Signaling and Circuitry (GRSNC), Université de Montréal, P.O. Box 6128, Station Downtown, QC, H3C 3J7, Montreal, Canada.; Lacaille JC

Subjects: Long-Term Potentiation*/Long-Term Potentiation*/Long-Term Potentiation*/physiology ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Spatial Learning*/Spatial Learning*/Spatial Learning*/physiology

  • Source: Molecular brain [Mol Brain] 2022 Dec 21; Vol. 15 (1), pp. 101. Date of Electronic Publication: 2022 Dec 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium:

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Academic Journal

The mTOR pathway controls phosphorylation of BRAF at T401.

  • Authors : Christen D; Institute of Molecular Medicine, University of Freiburg, Stefan-Meier-Str. 17, 79104, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.

Subjects: TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/metabolism ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/genetics

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 02; Vol. 22 (1), pp. 428. Date of Electronic Publication: 2024 Sep 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium:

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Academic Journal

mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination.

  • Authors : Khlaifia A; Department of Neurosciences, Center for Interdisciplinary Research on Brain and Learning (CIRCA) and Research Group On Neural Signaling and Circuitry (GRSNC), Université de Montréal, P.O. Box 6128, Station Downtown, QC, H3C 3J7, Montreal, Canada.; Department of Psychology, University of Toronto Scarborough, ON, M1C1A4, Toronto, Canada.

Subjects: CA1 Region, Hippocampal*/CA1 Region, Hippocampal*/CA1 Region, Hippocampal*/metabolism ; Fear*/Fear*/Fear*/physiology ; Hippocampus*/Hippocampus*/Hippocampus*/metabolism

  • Source: Molecular brain [Mol Brain] 2022 Jun 17; Vol. 15 (1), pp. 56. Date of Electronic Publication: 2022 Jun 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium:

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Academic Journal

Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease.

  • Authors : Pan B; Department of Nephrology, Wenzhou Central Hospital, Wenzhou, Zhejiang Province, China.; Teng Y

Subjects: Periodontitis*/Periodontitis*/Periodontitis*/genetics ; Periodontitis*/Periodontitis*/Periodontitis*/metabolism ; Periodontitis*/Periodontitis*/Periodontitis*/pathology

  • Source: BMC medical genomics [BMC Med Genomics] 2024 Jun 03; Vol. 17 (1), pp. 152. Date of Electronic Publication: 2024 Jun 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium:

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Academic Journal

Dietary resveratrol improves the flesh quality of Siberian sturgeon (Acipenser baerii) by enhancing myofiber growth, nutrient accumulation and antioxidant capacity.

  • Authors : Yang S; Department of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Chengdu, 611130, China.; Zhang J

Subjects: Resveratrol*/Resveratrol*/Resveratrol*/pharmacology ; Fishes*/Fishes*/Fishes*/metabolism ; Fishes*/Fishes*/Fishes*/growth & development

  • Source: BMC genomics [BMC Genomics] 2024 May 24; Vol. 25 (1), pp. 514. Date of Electronic Publication: 2024 May 24.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium:

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Academic Journal

Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity.

  • Authors : Villa-González M; Departamento de Biología (Fisiología Animal), Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, Spain.; Rubio M

Subjects: Microglia* ; Brain Ischemia*/Brain Ischemia*/Brain Ischemia*/drug therapy ; Brain Ischemia*/Brain Ischemia*/Brain Ischemia*/genetics

  • Source: Biology direct [Biol Direct] 2024 Apr 06; Vol. 19 (1), pp. 26. Date of Electronic Publication: 2024 Apr 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium:

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Academic Journal

Polyploidy and mTOR signaling: a possible molecular link.

  • Authors : Choudhury D; Department of Biomedical Science and Technology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational Research Institute (RKMVERI), Kolkata, India.; Ghosh D

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism ; Diabetes Mellitus*

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 27; Vol. 22 (1), pp. 196. Date of Electronic Publication: 2024 Mar 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium:

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Academic Journal

TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions.

  • Authors : Manandhar L; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.; Dutta RK

Subjects: Macroautophagy* ; Calcium*/Calcium*/Calcium*/metabolism; Reactive Oxygen Species/Reactive Oxygen Species/Reactive Oxygen Species/metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 21; Vol. 22 (1), pp. 142. Date of Electronic Publication: 2024 Feb 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium:

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  • 1-10 ل  201 نتائج ل ""Mechanistic Target of Rapamycin Complex 1""