نتائج البحث

A descriptive study of the single-nucleotide polymorphisms known to affect the Tacrolimus trough concentration per dose, among a population of kidney failure patients in a tertiary hospital in Ghana.

• Authors : Kwakyi E; Department of Medicine, University of Ghana Medical School, Legon, Ghana.; Nartey ET

Subjects: Polymorphism, Single Nucleotide*/Polymorphism, Single Nucleotide*/Polymorphism, Single Nucleotide*/genetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Tacrolimus*/Tacrolimus*/Tacrolimus*/pharmacokinetics

• Source: BMC research notes [BMC Res Notes] 2024 Jul 29; Vol. 17 (1), pp. 210. Date of Electronic Publication: 2024 Jul 29.Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium:

تفاصيل العنوان

Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI).

• Authors : Miyata S; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.; Department of Developmental and Regenerative Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.

Subjects: Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/genetics ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/metabolism ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/biosynthesis

• Source: Stem cell research & therapy [Stem Cell Res Ther] 2022 Jan 10; Vol. 13 (1), pp. 6. Date of Electronic Publication: 2022 Jan 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium:

تفاصيل العنوان

Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations.

• Authors : Thomford, Nicholas Ekow; Kellermann, Tracy; Biney, Robert Peter

Subjects: MALARIA; TREATMENT effectiveness; CYTOCHROME P-450SUB-Saharan Africa; GHANA

• Source: Malaria Journal; 4/29/2024, Vol. 23 Issue 1, p1-14, 14p

تفاصيل العنوان

Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua).

• Authors : Hasselberg, Linda¹ ; Grøsvik, Bjørn E.² ; Goksøyr, Anders^2,3

• Source: Comparative Hepatology. 2005, Vol. 4, p1-15. 15p. 2 Diagrams, 2 Charts, 4 Graphs.

تفاصيل العنوان

Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.

• Authors : Colón Ortiz, Rodnie; Knerler, Stephen; Fridman, Lisa B.

Subjects: COCAINE; MULTIDRUG resistance-associated proteins; ANTIRETROVIRAL agents

• Source: Fluids & Barriers of the CNS; 1/10/2024, Vol. 21 Issue 1, p1-27, 27p

تفاصيل العنوان

Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.

• Authors : Feng D; Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Tang T

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism ; Drugs, Chinese Herbal/Drugs, Chinese Herbal/Drugs, Chinese Herbal/*pharmacology

• Source: BMC complementary and alternative medicine [BMC Complement Altern Med] 2018 Dec 29; Vol. 18 (1), pp. 345. Date of Electronic Publication: 2018 Dec 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101088661 Publication Model: Electronic Cited Medium:

تفاصيل العنوان

Effect of breed and gender on bovine liver cytochrome P450 3A (CYP3A) expression and inter-species comparison with other domestic ruminants

• Authors : Dacasto, Mauro; EECKHOUTTE, Claudine; Capolongoa, Francesca

Subjects: ruminants; liver drug metabolism; CYP3A

• Source: ISSN: 0928-4249.

تفاصيل العنوان

Health care cost associated with the use of enzyme-inducing and non-enzyme-active antiepileptic drugs in the UK: a long-term retrospective matched cohort study.

• Authors : Borghs S; UCB Pharma, Slough, UK. .; Thieffry S

Subjects: Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/adverse effects ; Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/economics ; Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/therapeutic use

• Source: BMC neurology [BMC Neurol] 2017 Mar 23; Vol. 17 (1), pp. 59. Date of Electronic Publication: 2017 Mar 23.Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium:

تفاصيل العنوان

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes.

• Authors : Kern C; Division of Clinical Pharmacology & Toxicology, Department of Internal Medicine, University Hospital Bern, Bern, Switzerland.; Graduate School for Health Sciences, University of Bern, Bern, Switzerland.

Subjects: Anopheles* ; Insecticides*/Insecticides*/Insecticides*/pharmacology ; Malaria*/Malaria*/Malaria*/prevention & control

• Source: Malaria journal [Malar J] 2023 Jun 24; Vol. 22 (1), pp. 194. Date of Electronic Publication: 2023 Jun 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium:

تفاصيل العنوان

Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?

• Authors : Zhou Y; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, 111 Yi Xue Yuan Road, Shanghai, 200032, People's Republic of China.; Cao L

Subjects: Laparoscopy* ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/surgery

• Source: BMC anesthesiology [BMC Anesthesiol] 2023 May 22; Vol. 23 (1), pp. 173. Date of Electronic Publication: 2023 May 22.Publisher: BioMed Central Country of Publication: England NLM ID: 100968535 Publication Model: Electronic Cited Medium:

تفاصيل العنوان