نتائج البحث

Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism.

• Authors : Pham VN; Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.; Bruemmer KJ

Subjects: Carbon*/Carbon*/Carbon*/metabolism ; Epigenesis, Genetic*/Epigenesis, Genetic*/Epigenesis, Genetic*/drug effects ; S-Adenosylmethionine*/S-Adenosylmethionine*/S-Adenosylmethionine*/antagonists & inhibitors

• Source: Science (New York, N.Y.) [Science] 2023 Nov 03; Vol. 382 (6670), pp. eabp9201. Date of Electronic Publication: 2023 Nov 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.

• Authors : Berkovitch F; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Nicolet Y

Subjects: Biotin/Biotin/Biotin/*analogs & derivatives ; Biotin/Biotin/Biotin/*chemistry ; Escherichia coli/Escherichia coli/Escherichia coli/*enzymology

• Source: Science (New York, N.Y.) [Science] 2004 Jan 02; Vol. 303 (5654), pp. 76-9.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway.

• Authors : Xin Gu^1,2,3,4; Orozco, Jose M.^1,2,3,4; Saxton, Robert A.^1,2,3,4

• Source: Science. 11/10/2017, Vol. 358 Issue 6364, p813-818. 6p. 4 Diagrams.

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SAMTOR is an S -adenosylmethionine sensor for the mTORC1 pathway.

• Authors : Gu X; Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Subjects: Lysosomes/Lysosomes/Lysosomes/*enzymology ; Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/*metabolism ; S-Adenosylmethionine/S-Adenosylmethionine/S-Adenosylmethionine/*metabolism

• Source: Science (New York, N.Y.) [Science] 2017 Nov 10; Vol. 358 (6364), pp. 813-818.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.

• Authors : Schwalm EL; Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.; Grove TL

Subjects: Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*chemistry ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*ultrastructure ; Methyltransferases/Methyltransferases/Methyltransferases/*chemistry

• Source: Science (New York, N.Y.) [Science] 2016 Apr 15; Vol. 352 (6283), pp. 309-12.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation.

• Authors : Ng Shyh-Chang^1,2,3,4,5,6; Locasale, Jason W.^5,6; Lyssiotis, Costas A.^5,6

• Source: Science. 1/11/2013, Vol. 339 Issue 6116, p222-226. 5p.

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A Radically Different Mechanism for S-Adenosylmethionine-Dependent Methyltransferases.

• Authors : Grove, Tyler L.¹; Benner, Jack S.²; Radle, Matthew I.¹

• Source: Science. 4/29/2011, Vol. 332 Issue 6029, p604-607. 4p.

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Influence of threonine metabolism on S-adenosylmethionine and histone methylation.

• Authors : Shyh-Chang N; Stem Cell Transplantation Program, Division of Pediatric Hematology and Oncology, Manton Center for Orphan Disease Research, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Locasale JW

Subjects: Embryonic Stem Cells/Embryonic Stem Cells/Embryonic Stem Cells/*cytology ; Embryonic Stem Cells/Embryonic Stem Cells/Embryonic Stem Cells/*metabolism ; Histones/Histones/Histones/*metabolism

• Source: Science (New York, N.Y.) [Science] 2013 Jan 11; Vol. 339 (6116), pp. 222-6. Date of Electronic Publication: 2012 Nov 01.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.

• Authors : Dong M; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.; Kathiresan V

Subjects: Archaeal Proteins/Archaeal Proteins/Archaeal Proteins/*chemistry ; Histidine/Histidine/Histidine/*analogs & derivatives ; Iron-Sulfur Proteins/Iron-Sulfur Proteins/Iron-Sulfur Proteins/*chemistry

• Source: Science (New York, N.Y.) [Science] 2018 Mar 16; Vol. 359 (6381), pp. 1247-1250.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.

• Authors : Horitani M; Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.; Shisler K

Subjects: Biocatalysis*; Enzymes/Enzymes/Enzymes/*chemistry ; Iron-Sulfur Proteins/Iron-Sulfur Proteins/Iron-Sulfur Proteins/*chemistry

• Source: Science (New York, N.Y.) [Science] 2016 May 13; Vol. 352 (6287), pp. 822-5. Date of Electronic Publication: 2016 May 12.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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