نتائج البحث

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis.

• Authors : Burdziak C; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10065, USA.

Subjects: Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/pathology ; Epigenesis, Genetic*

• Source: Science (New York, N.Y.) [Science] 2023 May 12; Vol. 380 (6645), pp. eadd5327. Date of Electronic Publication: 2023 May 12.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.

• Authors : Chun-on, Pattra^1,2,3; Hinchie, Angela M.¹; Beale, Holly C.^4,5

• Source: Science. 11/11/2022, Vol. 378 Issue 6620, p664-668. 5p. 1 Color Photograph, 3 Diagrams.

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The melanoma revolution: from UV carcinogenesis to a new era in therapeutics.

• Authors : Lo JA; Cutaneous Biology Research Center, Department of Dermatology and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Fisher DE

Subjects: Molecular Targeted Therapy*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*pathology ; Melanocytes/Melanocytes/Melanocytes/*pathology

• Source: Science (New York, N.Y.) [Science] 2014 Nov 21; Vol. 346 (6212), pp. 945-9.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Oncometabolite d-2HG alters T cell metabolism to impair CD8 + T cell function.

• Authors : Notarangelo G; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Spinelli JB

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics

• Source: Science (New York, N.Y.) [Science] 2022 Sep 30; Vol. 377 (6614), pp. 1519-1529. Date of Electronic Publication: 2022 Sep 29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations.

• Authors : Peycheva M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter, 1030 Vienna, Austria.; Neumann T

Subjects: Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics ; DNA Replication Timing* ; Lymphoma, B-Cell*/Lymphoma, B-Cell*/Lymphoma, B-Cell*/genetics

• Source: Science (New York, N.Y.) [Science] 2022 Sep 16; Vol. 377 (6612), pp. eabj5502. Date of Electronic Publication: 2022 Sep 16.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.

• Authors : Del Poggetto E; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Ho IL

Subjects: Carcinogenesis* ; Genes, ras*; Acinar Cells/Acinar Cells/Acinar Cells/*pathology

• Source: Science (New York, N.Y.) [Science] 2021 Sep 17; Vol. 373 (6561), pp. eabj0486. Date of Electronic Publication: 2021 Sep 17.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation.

• Authors : Martin TD; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Patel RS

Subjects: Carcinogenesis* ; Gene Silencing* ; Genes, Tumor Suppressor*

• Source: Science (New York, N.Y.) [Science] 2021 Sep 17; Vol. 373 (6561), pp. 1327-1335. Date of Electronic Publication: 2021 Sep 16.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice.

• Authors : Bergers, Gabriele; Javaherian, Kashi; Lo, Kin-Ming

• Source: Science. 4/30/1999, Vol. 284 Issue 5415, p808-812. 5p. 9 Color Photographs, 1 Diagram, 2 Charts, 3 Graphs.

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How safe is a popular gene therapy vector?

• Authors : Kaiser J

Subjects: Carcinogenesis* ; Dependovirus*; Genetic Therapy/Genetic Therapy/Genetic Therapy/*adverse effects

• Source: Science (New York, N.Y.) [Science] 2020 Jan 10; Vol. 367 (6474), pp. 131.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Cell proliferation in carcinogenesis.

• Authors : Cohen, S.M.; Ellwein, L.B.

• Source: Science. 8/31/1990, Vol. 249 Issue 4972, p1007. 5p. 2 Diagrams, 2 Graphs.

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