نتائج البحث

Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion

• Authors : Fumagalli, Valeria; Ravà, Micol; Marotta, Davide ...

Subjects: Administration; Inhalation; Angiotensin-Converting Enzyme 2

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Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

• Authors : Tortorici M. A.; Beltramello M.; Lempp F. A. ...

Subjects: Amino Acid Motif; Angiotensin-Converting Enzyme 2; Animal

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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

• Authors : Zhongpeng Zhao; Shaolong Chen; Jiangfan Li

Subjects: 0301 basic medicine; viruses; Mice

• Source: Science (New York, N.y.)Science

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Protein storytelling through physics.

• Authors : Brini E; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY 11794, USA.; Simmerling C

Subjects: Computer Simulation* ; Models, Molecular* ; Proteins*

• Source: Science (New York, N.Y.) [Science] 2020 Nov 27; Vol. 370 (6520).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.

• Authors : Cantuti-Castelvetri L; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Subjects: Virus Internalization*; Betacoronavirus/Betacoronavirus/Betacoronavirus/*physiology ; Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*virology

• Source: Science (New York, N.Y.) [Science] 2020 Nov 13; Vol. 370 (6518), pp. 856-860. Date of Electronic Publication: 2020 Oct 20.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Neuropilin-1 is a host factor for SARS-CoV-2 infection.

• Authors : Daly JL; School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.; Simonetti B

Subjects: Virus Internalization*; Betacoronavirus/Betacoronavirus/Betacoronavirus/*physiology ; Neuropilin-1/Neuropilin-1/Neuropilin-1/*metabolism

• Source: Science (New York, N.Y.) [Science] 2020 Nov 13; Vol. 370 (6518), pp. 861-865. Date of Electronic Publication: 2020 Oct 20.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.

• Authors : Toelzer C; School of Biochemistry, University of Bristol, 1 Tankard's Close, Bristol BS8 1TD, UK.; Bristol Synthetic Biology Centre BrisSynBio, 24 Tyndall Ave., Bristol BS8 1TQ, UK.

Subjects: Linoleic Acid/Linoleic Acid/Linoleic Acid/*metabolism ; Spike Glycoprotein, Coronavirus/Spike Glycoprotein, Coronavirus/Spike Glycoprotein, Coronavirus/*chemistry; Amino Acid Sequence

• Source: Science (New York, N.Y.) [Science] 2020 Nov 06; Vol. 370 (6517), pp. 725-730. Date of Electronic Publication: 2020 Sep 21.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.

• Authors : Cao L; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.

Subjects: Drug Design*; Antiviral Agents/Antiviral Agents/Antiviral Agents/*chemistry ; Betacoronavirus/Betacoronavirus/Betacoronavirus/*drug effects

• Source: Science (New York, N.Y.) [Science] 2020 Oct 23; Vol. 370 (6515), pp. 426-431. Date of Electronic Publication: 2020 Sep 09.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.

• Authors : Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.; Chen Q

Subjects: Disease Models, Animal* ; Mice*; Betacoronavirus/Betacoronavirus/Betacoronavirus/*immunology

• Source: Science (New York, N.Y.) [Science] 2020 Sep 25; Vol. 369 (6511), pp. 1603-1607. Date of Electronic Publication: 2020 Jul 30.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Distinct conformational states of SARS-CoV-2 spike protein.

• Authors : Cai Y; Division of Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

Subjects: Host-Pathogen Interactions/Host-Pathogen Interactions/Host-Pathogen Interactions/*immunology ; Spike Glycoprotein, Coronavirus/Spike Glycoprotein, Coronavirus/Spike Glycoprotein, Coronavirus/*chemistry; Angiotensin-Converting Enzyme 2

• Source: Science (New York, N.Y.) [Science] 2020 Sep 25; Vol. 369 (6511), pp. 1586-1592. Date of Electronic Publication: 2020 Jul 21.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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