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Academic Journal

A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model.

Authors : Takeda, Kenji^1,2 (AUTHOR) ; Sakai-Sakasai, Akiko¹ (AUTHOR) ; Kajinami, Kouji² (AUTHOR)

Source: Cells (2073-4409). Dec2023, Vol. 12 Issue 24, p2838. 26p.

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Academic Journal

Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo.

Authors : Baran, Vladimír¹ (AUTHOR) ; Mayer, Alexandra² (AUTHOR)

Source: International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 7, p6778. 15p.

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Academic Journal

Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).

Authors : Li, Xicai¹ (AUTHOR); Huang, Jingquan¹ (AUTHOR); Wu, Qiulin¹ (AUTHOR)

Source: Cancers. Feb2023, Vol. 15 Issue 3, p850. 15p.

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Academic Journal

Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent.

Authors : Chinyama, Harold A.¹ (AUTHOR) ; Wei, Li^2,3,4 (AUTHOR) ; Mokgautsi, Ntlotlang^5,6 (AUTHOR)

Source: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 22, p16396. 18p.

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Academic Journal

Overexpression of CHK1 and CHK2 in pediatric patients of B -acute lymphoblastic leukemia.

Authors : Heidari, Farshad¹; Faranoush, Mohammad²; Amini, Ali¹

Source: Iranian Journal of Pediatric Hematology & Oncology. 2023, Vol. 13 Issue 4, p233-240. 7p.

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Academic Journal

Orchestrating smart therapeutics to achieve optimal treatment in small cell lung cancer: recent progress and future directions.

Authors : Zhang, Chenyue¹ (AUTHOR); Zhang, Chenxing² (AUTHOR); Wang, Kai³ (AUTHOR)

Source: Journal of Translational Medicine. 7/14/2023, Vol. 21 Issue 1, p1-18. 18p.

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Academic Journal

Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.

Authors : Lynch, Katherine D.¹ (AUTHOR) ; Iverson, Dayne T.¹ (AUTHOR); Bachhav, Namrata K.¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p11168. 18p.

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Academic Journal

A Multimodel Study of the Role of Novel PKC Isoforms in the DNA Integrity Checkpoint.

Authors : Saiz-Baggetto, Sara^1,2 (AUTHOR) ; Dolz-Edo, Laura^1,2,3 (AUTHOR) ; Méndez, Ester^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 21, p15796. 23p.

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Academic Journal

Correction: Hsiao et al. Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses. Biomolecules 2023, 13 , 125.

Authors : Hsiao, Hao-Wen^1,2 (AUTHOR) ; Yang, Chi-Chun¹ (AUTHOR) ; Masai, Hisao^1,2 (AUTHOR)

Source: Biomolecules (2218-273X). Jul2023, Vol. 13 Issue 7, p1145. 5p.

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Academic Journal

When more is less: heritable gain‐of‐function chk1 mutations impair human fertility.

Authors : Gillespie, David A.¹ (AUTHOR)

Source: FEBS Journal. Apr2023, Vol. 290 Issue 7, p1719-1724. 6p.

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فلترة النتائج

A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model.

Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo.

Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).

Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent.

Overexpression of CHK1 and CHK2 in pediatric patients of B -acute lymphoblastic leukemia.

Orchestrating smart therapeutics to achieve optimal treatment in small cell lung cancer: recent progress and future directions.

Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.

A Multimodel Study of the Role of Novel PKC Isoforms in the DNA Integrity Checkpoint.

Correction: Hsiao et al. Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses. Biomolecules 2023, 13 , 125.

When more is less: heritable gain‐of‐function chk1 mutations impair human fertility.

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