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Academic Journal

Thiosemicarbazones Can Act Synergistically with Anthracyclines to Downregulate CHEK1 Expression and Induce DNA Damage in Cell Lines Derived from Pediatric Solid Tumors.

Authors : Paukovcekova, Silvia¹ (AUTHOR) ; Krchniakova, Maria^1,2 (AUTHOR) ; Chlapek, Petr^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Aug2022, Vol. 23 Issue 15, p8549-8549. 19p.

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Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling.

Authors : Batzilla, Alina^1,2 (AUTHOR); Lu, Junyan^1,3,4 (AUTHOR) ; Kivioja, Jarno⁵ (AUTHOR)

Source: PLoS Computational Biology. 8/22/2022, Vol. 18 Issue 8, p1-19. 19p. 2 Diagrams, 2 Graphs.

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Academic Journal

PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells.

Authors : Lee, Sol¹ (AUTHOR); Jee, Ha-Yeon¹ (AUTHOR); Lee, Yoon-Gyeong¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p15872. 15p.

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Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.

Authors : Tomic, Barbara^1,2 (AUTHOR); Smoljo, Tomislav^1,2 (AUTHOR); Lalic, Hrvoje^1,2 (AUTHOR)

Source: Scientific Reports. 7/5/2022, Vol. 12 Issue 1, p1-16. 16p.

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Academic Journal

Brooding Temperature Alters Yolk Sac Absorption and Affected Ovarian Development in Goslings.

Authors : Liu, Zhengquan¹ (AUTHOR) ; Chen, Xingyong^1,2 (AUTHOR) ; Zhao, Yutong¹ (AUTHOR)

Source: Animals (2076-2615). Jun2022, Vol. 12 Issue 12, p1513. 11p.

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Academic Journal

Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer.

Authors : Sun, Jie¹ (AUTHOR); Li, Mei¹ (AUTHOR); Lin, Tingru^1,2 (AUTHOR)

Source: Scientific Reports. 3/14/2022, Vol. 12 Issue 1, p1-16. 16p.

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p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor.

Authors : Levesque, Aime A.¹ (AUTHOR) ; Pappalardo, Rebecca M.¹ (AUTHOR); Puli, Pawan¹ (AUTHOR)

Source: PLoS ONE. 2/10/2022, Vol. 17 Issue 2, p1-14. 14p.

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Relative free-energy calculations for scaffold hopping-type transformations with an automated RE-EDS sampling procedure.

Authors : Ries, Benjamin¹ (AUTHOR); Normak, Karl¹ (AUTHOR); Weiß, R. Gregor¹ (AUTHOR)

Source: Journal of Computer-Aided Molecular Design. Feb2022, Vol. 36 Issue 2, p117-130. 14p.

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Relationship between DNA mismatch repair and CRISPR/Cas9-mediated knock-in in the bovine β-casein gene locus.

Authors : Seung-Yeon Kim¹; Ga-Yeon Kim¹; Hyeong-Ju You¹

Source: Animal Bioscience. Jan2022, Vol. 35 Issue 1, p126-137. 12p.

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Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy.

Authors : Nickoloff, Jac A.¹ (AUTHOR)

Source: Molecules. Aug2022, Vol. 27 Issue 15, p4736-4736. 19p.

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فلترة النتائج

Thiosemicarbazones Can Act Synergistically with Anthracyclines to Downregulate CHEK1 Expression and Induce DNA Damage in Cell Lines Derived from Pediatric Solid Tumors.

Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling.

PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells.

Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.

Brooding Temperature Alters Yolk Sac Absorption and Affected Ovarian Development in Goslings.

Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer.

p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor.

Relative free-energy calculations for scaffold hopping-type transformations with an automated RE-EDS sampling procedure.

Relationship between DNA mismatch repair and CRISPR/Cas9-mediated knock-in in the bovine β-casein gene locus.

Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy.

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