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Academic Journal

Dihydropyrimidine dehydrogenase level and the redox status in patients with colorectal cancer are prognostic for adverse effects of fluoropyrimidines.

Authors : Hristova-Avakumova, Nadya G.¹ (AUTHOR); Minchev, Velko T.² (AUTHOR); Kamenova, Kalina V.³ (AUTHOR)

Source: Biotechnology & Biotechnological Equipment. 2021, Vol. 35 Issue 1, p1247-1255. 9p.

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Academic Journal

Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events.

Authors : Wigle, Theodore J.¹ (AUTHOR); Povitz, Brandi L.² (AUTHOR); Medwid, Samantha^1,3 (AUTHOR)

Source: CTS: Clinical & Translational Science. Jul2021, Vol. 14 Issue 4, p1338-1348. 11p.

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Academic Journal

Dihydropyrimidine dehydrogenase deficiency in patients with severe toxicity after 5-fluorouracil: a retrospective single-center study.

Authors : Detailleur, Stephanie¹; Segelov, Eva²; Re, Marzia Del³

Source: Annals of Gastroenterology. 2021, Vol. 34 Issue 1, p68-72. 5p.

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Academic Journal

An in vitro approach to simulate the process of 5-fluorouracil degradation with dihydropyrimidine dehydrogenase: the process in accordance to the first-order kinetic reaction.

Authors : Qin, Wei¹ (AUTHOR); Wang, Xiaoxue¹ (AUTHOR); Chen, Wenqian¹ (AUTHOR)

Source: Xenobiotica. Jan2021, Vol. 51 Issue 1, p24-30. 7p.

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Academic Journal

Overexpression and characterization of Escherichia coli dihydropyrimidine dehydrogenase: a four iron-sulphur cluster containing flavoprotein.

Authors : Yoshioka, Hiroshi¹ (AUTHOR); Ishida, Tetsuo² (AUTHOR); Mihara, Hisaaki¹ (AUTHOR)

Source: Journal of Biochemistry. Oct2021, Vol. 170 Issue 4, p511-520. 10p.

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Academic Journal

Fluoropyrimidine-Induced Severe Toxicities Associated with Rare DPYD Polymorphisms: Case Series from Saudi Arabia and a Review of the Literature.

Authors : Bukhari, Nedal^1,2 ; Alshangiti, Abdulraheem¹ ; Tashkandi, Emad^3,4

Source: Clinics & Practice. 2021, Vol. 11 Issue 3, p467-471. 5p.

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Academic Journal

Near Miss or Standard of Care? DPYD Screening for Cancer Patients Receiving Fluorouracil.

Authors : Winquist, Lauren E.¹ ; Sanatani, Michael^1,2 ; Kim, Richard B.^1,3

Source: Current Oncology. Feb2021, Vol. 28 Issue 1, p94-97. 4p.

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Combined use of 177Lu-DOTATATE and metronomic capecitabine (Lu-X) in FDG-positive gastro-entero-pancreatic neuroendocrine tumors.

Authors : Nicolini, Silvia¹ (AUTHOR); Bodei, Lisa² (AUTHOR); Bongiovanni, Alberto³ (AUTHOR)

Source: European Journal of Nuclear Medicine & Molecular Imaging. Sep2021, Vol. 48 Issue 10, p3260-3267. 8p. 1 Color Photograph, 1 Chart, 2 Graphs.

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Academic Journal

Force Field Parameters for Fe 2+ 4 S 2− 4 Clusters of Dihydropyrimidine Dehydrogenase, the 5-Fluorouracil Cancer Drug Deactivation Protein: A Step towards In Silico Pharmacogenomics Studies.

Authors : Tendwa, Maureen Bilinga¹ (AUTHOR) ; Chebon-Bore, Lorna¹ (AUTHOR) ; Lobb, Kevin^1,2 (AUTHOR)

Source: Molecules. May2021, Vol. 26 Issue 10, p2929-2929. 1p.

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Academic Journal

Analysis of very important pharmacogene variants in the Tibetan population from China.

Authors : Rong, Hao^1,2 (AUTHOR); Dong, Hongzhi³ (AUTHOR); He, Xue¹ (AUTHOR)

Source: Clinical & Experimental Pharmacology & Physiology. May2021, Vol. 48 Issue 5, p668-678. 11p. 8 Charts, 3 Graphs.

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فلترة النتائج

Dihydropyrimidine dehydrogenase level and the redox status in patients with colorectal cancer are prognostic for adverse effects of fluoropyrimidines.

Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events.

Dihydropyrimidine dehydrogenase deficiency in patients with severe toxicity after 5-fluorouracil: a retrospective single-center study.

An in vitro approach to simulate the process of 5-fluorouracil degradation with dihydropyrimidine dehydrogenase: the process in accordance to the first-order kinetic reaction.

Overexpression and characterization of Escherichia coli dihydropyrimidine dehydrogenase: a four iron-sulphur cluster containing flavoprotein.

Fluoropyrimidine-Induced Severe Toxicities Associated with Rare DPYD Polymorphisms: Case Series from Saudi Arabia and a Review of the Literature.

Near Miss or Standard of Care? DPYD Screening for Cancer Patients Receiving Fluorouracil.

Combined use of 177Lu-DOTATATE and metronomic capecitabine (Lu-X) in FDG-positive gastro-entero-pancreatic neuroendocrine tumors.

Force Field Parameters for Fe 2+ 4 S 2− 4 Clusters of Dihydropyrimidine Dehydrogenase, the 5-Fluorouracil Cancer Drug Deactivation Protein: A Step towards In Silico Pharmacogenomics Studies.

Analysis of very important pharmacogene variants in the Tibetan population from China.

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