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Academic Journal

Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells.

Authors : Hye-yon Cho^1,2; Yong-Beom Kim^1,3 ; Wook-ha Park³

Source: Cancer Research & Treatment. Jul2021, Vol. 53 Issue 3, p819-828. 10p.

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Academic Journal

Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells.

Authors : Park, So‐Yeon^1,2 (AUTHOR); Kim, Jee‐Heun¹ (AUTHOR); Choi, Jang‐Hyun¹ (AUTHOR)

Source: Clinical & Translational Medicine. Nov2021, Vol. 11 Issue 11, p1-29. 29p.

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Academic Journal

Fms-like tyrosine kinase 3-internal tandem duplications epigenetically activates checkpoint kinase 1 in acute myeloid leukemia cells.

Authors : Zhang, Yudong¹; Yuan, Lingli²

Source: Scientific Reports. 6/24/2021, Vol. 11 Issue 1, p1-9. 9p.

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Academic Journal

Inhibition of checkpoint kinase 1 potentiates anticancer activity of gemcitabine in bladder cancer cells.

Authors : Isono, Makoto¹ ; Okubo, Kazuki¹; Asano, Takako¹

Source: Scientific Reports. 5/13/2021, Vol. 11 Issue 1, p1-8. 8p.

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Academic Journal

Candida albicans CHK1 gene from two-component system is essential for its pathogenicity in oral candidiasis.

Authors : Zhou, Yujie^1,2 (AUTHOR); Cheng, Lei^1,2 (AUTHOR); Liao, Binyou¹ (AUTHOR)

Source: Applied Microbiology & Biotechnology. Mar2021, Vol. 105 Issue 6, p2485-2496. 12p.

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Academic Journal

GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2+ Macrophage Infiltration in Mice.

Authors : Li, Min (AUTHOR); Huang, Tianqing (AUTHOR); Li, Xiaolan (AUTHOR)

Source: OncoTargets & Therapy. Apr2021, Vol. 14, p2661-2672. 12p.

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Academic Journal

19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), an ent-abietane diterpene diepoxide, inhibits the growth of bladder cancer T24 cells through DNA damage.

Authors : Wang, Ke^1,2,3 (AUTHOR); Yang, Juan-Cheng⁴ (AUTHOR); Jang, Yeong-Jiunn⁴ (AUTHOR)

Source: PLoS ONE. 3/16/2021, Vol. 16 Issue 3, p1-24. 24p.

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Academic Journal

Synergistic targeting of CHK1 and mTOR in MYC-driven tumors.

Authors : Song, Xiaoxue^1,2 (AUTHOR); Wang, Liyuan^1,2 (AUTHOR); Wang, Tianci² (AUTHOR)

Source: Carcinogenesis. Mar2021, Vol. 42 Issue 3, p448-460. 13p.

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Academic Journal

Oat (Avena sativa) Extract against Oxidative Stress-Induced Apoptosis in Human Keratinocytes.

Authors : Song, Sooji¹ (AUTHOR) ; Lee, Yoon-Mi^1,2 (AUTHOR) ; Lee, Yu Young³ (AUTHOR)

Source: Molecules. Sep2021, Vol. 26 Issue 18, p5564. 1p.

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Academic Journal

Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression.

Authors : Proctor, Martina¹ (AUTHOR) ; Gonzalez Cruz, Jazmina L.² (AUTHOR) ; Daignault-Mill, Sheena M.² (AUTHOR)

Source: Cancers. Aug2021, Vol. 13 Issue 15, p3733-3733. 1p.

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فلترة النتائج

Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells.

Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells.

Fms-like tyrosine kinase 3-internal tandem duplications epigenetically activates checkpoint kinase 1 in acute myeloid leukemia cells.

Inhibition of checkpoint kinase 1 potentiates anticancer activity of gemcitabine in bladder cancer cells.

Candida albicans CHK1 gene from two-component system is essential for its pathogenicity in oral candidiasis.

GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2+ Macrophage Infiltration in Mice.

19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), an ent-abietane diterpene diepoxide, inhibits the growth of bladder cancer T24 cells through DNA damage.

Synergistic targeting of CHK1 and mTOR in MYC-driven tumors.

Oat (Avena sativa) Extract against Oxidative Stress-Induced Apoptosis in Human Keratinocytes.

Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression.

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