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Academic Journal

Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 Downregulation.

Authors : Choi, Changhoon¹ (AUTHOR) ; Cho, Won Kyung¹ (AUTHOR) ; Park, Sohee¹ (AUTHOR)

Source: International Journal of Molecular Sciences. 4/15/2020, Vol. 21 Issue 8, p2691-2691. 1p. 5 Graphs.

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Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer.

Authors : Nieto-Jimenez, Cristina^1,2 (AUTHOR) ; Alcaraz-Sanabria, Ana¹ (AUTHOR) ; Martinez-Canales, Sandra^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2020, Vol. 21 Issue 23, p9034. 1p.

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Academic Journal

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

Authors : Arroyo, Maria¹ (AUTHOR); Cañuelo, Ana¹ (AUTHOR); Calahorra, Jesús¹ (AUTHOR)

Source: FEBS Journal. Nov2020, Vol. 287 Issue 22, p4933-4951. 19p.

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Academic Journal

Regulation of CHK1 by the Ubiquitin–Proteasome System.

Authors : Cartel, Maëlle^1,2 (AUTHOR); Didier, Christine^1,2 (AUTHOR)

Source: FEBS Journal. May2020, Vol. 287 Issue 10, p1982-1984. 3p.

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Academic Journal

CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos.

Authors : Ju, Jia‐Qian¹ (AUTHOR); Li, Xiao‐Han¹ (AUTHOR); Pan, Meng‐Hao¹ (AUTHOR)

Source: Cell Proliferation. Oct2020, Vol. 53 Issue 10, p1-12. 12p.

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Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer.

Authors : Meyer, Felix¹ ; Becker, Saskia¹ ; Classen, Sandra¹

Source: Cells (2073-4409). Jan2020, Vol. 9 Issue 1, p1-17. 26p.

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Academic Journal

HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1.

Authors : Moses, Niko¹ (AUTHOR) ; Zhang, Mu² (AUTHOR) ; Wu, Jheng-Yu² (AUTHOR)

Source: Cells (2073-4409). Oct2020, Vol. 9 Issue 10, p2237. 1p.

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Fumonisin B 1 Epigenetically Regulates PTEN Expression and Modulates DNA Damage Checkpoint Regulation in HepG2 Liver Cells.

Authors : Arumugam, Thilona¹ (AUTHOR) ; Ghazi, Terisha¹ (AUTHOR); Chuturgoon, Anil¹ (AUTHOR)

Source: Toxins. Oct2020, Vol. 12 Issue 10, p625. 1p.

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Academic Journal

polysaccharides exert an antioxidative effect on rat chondrocytes by activating the nuclear factor (erythroid-derived 2)-like 2 signaling pathway.

Authors : Yu Chen¹; Qing Bi¹; Ziguan Zhu²

Source: Archives of Medical Science. 2020, Vol. 16 Issue 4, p964-973. 10p.

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Academic Journal

Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modelling and Molecular Docking.

Authors : AL-SHAR'I, N. A.¹ ; MUSLEH, SONDOS¹

Source: Indian Journal of Pharmaceutical Sciences. 2020, Vol. 82 Issue 3, p472-482. 11p.

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فلترة النتائج

Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 Downregulation.

Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer.

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

Regulation of CHK1 by the Ubiquitin–Proteasome System.

CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos.

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer.

HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1.

Fumonisin B 1 Epigenetically Regulates PTEN Expression and Modulates DNA Damage Checkpoint Regulation in HepG2 Liver Cells.

polysaccharides exert an antioxidative effect on rat chondrocytes by activating the nuclear factor (erythroid-derived 2)-like 2 signaling pathway.

Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modelling and Molecular Docking.

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