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The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Substitutions on Substrate Specificity

• Authors : Abigail V. Sharrock; Jeff S. Mumm; Gintautas Bagdžiūnas

Subjects: Inorganic Chemistry; type I nitroreductase; NfsB

• Source: International journal of molecular sciences, Basel : MDPI, 2023, vol. 24, iss. 7, art. no. 6633, p. [1-16]International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6633

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CytoCy5S™, a compound of many structures. in vitro and in vivo evaluation of four near-infrared fluorescent substrates of nitroreductase (NTR)

• Authors : Bengt Erik Haug; Gorka Ruiz de Garibay; Elvira García de Jalón

Subjects: Reporter gene; medicine.diagnostic_test; Chemistry

• Source: Dyes and pigments

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A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons

• Authors : Michelle R. Arkin; Harrison Liu; Mannuel Elepano

Subjects: melanogaster; Aging; Databases, Factual

• Source: eLife, Vol 10 (2021)

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Redox Coenzyme F 420 Biosynthesis in Thermomicrobia Involves Reduction by Stand-Alone Nitroreductase Superfamily Enzymes

• Authors : Mahmudul Hasan; Tabea Kröber; Gerald Lackner

Subjects: chemistry.chemical_classification; 0303 health sciences; Ecology

• Source: Applied and Environmental Microbiology. 86

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Redox Coenzyme F

• Authors : Daniel, Braga; Mahmudul, Hasan; Tabea, Kröber

Subjects: Riboflavin; Chloroflexi; Nitroreductases

• Source: Appl Environ Microbiol

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Synthesis and biological evaluation of prodrugs for nitroreductase based HSP90 inhibitor BIIB021as potential anticancer agents

• Authors : Zhengrong Wu; Peng Jing; Wei Deng

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A Highly Selective Fluorescent Probe for the Detection of Nitroreductase Based on a Naphthalimide Scaffold

• Authors : Han, Li; Feng, Jintao; Zhen, Wang

Subjects: Naphthalimides; Clinical Psychology; Microscopy, Fluorescence

• Source: Journal of Fluorescence. 32:1825-1832

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A New Transgenic Line for Rapid and Complete Neutrophil Ablation

• Authors : Christopher J. Hall; Jonathan W. Astin; Jeff S. Mumm

Subjects: Animals, Genetically Modified; Neutrophils; Metronidazole

• Source: Zebrafish

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Data from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer

• Authors : Bjørn Tore Gjertsen; Michael E. Cooper; Bengt Erik Haug

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Data from Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

• Authors : J. Martin Brown; Adam V. Patterson; Mary-Jo Dorie

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