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Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain

• Authors : Hanjing Yang; Josue Pacheco; Kyumin Kim

Subjects: Gene Editing; Models, Molecular; Science

• Source: Nat CommunNature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

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Aromatic residues in N-terminal domain of archaeal trehalase affect the folding and activity of catalytic domain

• Authors : Takumi Sakoh; Nagisa Satoh; Yumeka Domon

Subjects: Protein Folding; Amino Acids, Aromatic; Amino Acid Substitution

• Source: Appl Microbiol Biotechnol

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Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer Therapeutics

• Authors : Minh Quan Nguyen; Do Hyung Kim; Hye Ji Shim

Subjects: ADP Ribose Transferases; Immunotoxins; Recombinant Fusion Proteins

• Source: Mol Cells

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Structural and Evolutionary Analysis of Proteins Endowed with a Nucleotidyltransferase, or Non-canonical Palm, Catalytic Domain

• Authors : Rodrigo Jácome

Subjects: Original Article

• Source: J Mol Evol

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Allosteric Communication of the Dimerization and the Catalytic Domain in Photoreceptor Guanylate Cyclase

• Authors : Manisha Kumari Shahu; Fabian Schuhmann; Siu Ying Wong

• Source: BiochemistryShahu, M K, Schuhmann, F, Wong, S Y, Solov’yov, I A & Koch, K 2024, ' Allosteric Communication of the Dimerization and the Catalytic

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The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation

• Authors : Markus Schweipert; Thomas Nehls; Anton Frühauf

Subjects: Zinc; 0303 health sciences; 03 medical and health sciences

• Source: Protein Sci

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Bacterial Production of CDKL5 Catalytic Domain: Insights in Aggregation, Internal Translation and Phosphorylation Patterns

• Authors : Andrea Colarusso; Concetta Lauro; Luisa Canè

Subjects: 0303 health sciences; Protein Serine-Threonine Kinases; Article

• Source: Int J Mol Sci

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Undetectable off-target effects induced by FokI catalytic domain in mouse embryos

• Authors : Long Xie; Hu Feng; Zhifang Li

Subjects: Gene Editing; Genome; QH301-705.5

• Source: Genome BiolGenome Biology, Vol 25, Iss 1, Pp 1-12 (2024)

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Discovery of first-in-class DOT1L inhibitors against the R231Q gain-of-function mutation in the catalytic domain with therapeutic potential of lung cancer

• Authors : Zehui Tan; Ning Guo; Zhi Cao

Subjects: 0301 basic medicine; 03 medical and health sciences; Adenosine-containing inhibitors

• Source: Acta Pharm Sin BActa Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3605-3623 (2024)

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Understanding ATP binding to DosS catalytic domain with a short ATP-lid

• Authors : Grant W. Larson; Peter K. Windsor; Elizabeth Smithwick

Subjects: Adenosine Triphosphate; Histidine Kinase; Bacterial Proteins

• Source: bioRxiv

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