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Amphetamine Derivatives as Potent Central Nervous System Multitarget SERT/NET/H 3 Agents: Synthesis and Biological Evaluation.

• Authors : Li Q; School of Pharmacy, Nanjing Tech University, 30th South Puzhu Road, Nanjing 211816, China.; Ren L

Subjects: Molecular Docking Simulation* ; Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/metabolism ; Receptors, Histamine H3*/Receptors, Histamine H3*/Receptors, Histamine H3*/metabolism

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 06; Vol. 29 (22). Date of Electronic Publication: 2024 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Design and Synthesis of Potential Multi-Target Antidepressants: Exploration of 1-(4-(7-Azaindole)-3,6-dihydropyridin-1-yl)alkyl-3-(1 H -indol-3-yl)pyrrolidine-2,5-dione Derivatives with Affinity for the Serotonin Transporter.

• Authors : Wróbel MZ; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warszawa, Poland.; Chodkowski A

Subjects: Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/metabolism ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/chemistry

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 20; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Updating view of membrane transport proteins by simulation studies.

• Authors : Takashi Sumikama^1,2 ; Ben Corry³; Junichi Ono⁴

• Source: Biophysics & Physicobiology. 2023, Vol. 20 Issue 4, p1-4. 4p.

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Effects of SRI-32743, a Novel Quinazoline Structure-Based Compound, on HIV-1 Tat and Cocaine Interaction with Norepinephrine Transporter.

• Authors : Jiménez-Torres AC; Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, 715 Sumter Street, Columbia, SC 29208, USA.; Porter KD

Subjects: Norepinephrine Plasma Membrane Transport Proteins*/Norepinephrine Plasma Membrane Transport Proteins*/Norepinephrine Plasma Membrane Transport Proteins*/metabolism ; tat Gene Products, Human Immunodeficiency Virus*/tat Gene Products, Human Immunodeficiency Virus*/tat Gene Products, Human Immunodeficiency Virus*/metabolism ; tat Gene Products, Human Immunodeficiency Virus*/tat Gene Products, Human Immunodeficiency Virus*/tat Gene Products, Human Immunodeficiency Virus*/chemistry

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 18; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Development and Characterization of a Human Mammary Epithelial Cell Culture Model for the Blood–Milk Barrier—A Contribution from the ConcePTION Project.

• Authors : La Mantia, Debora¹ (AUTHOR) ; Nauwelaerts, Nina² (AUTHOR) ; Bernardini, Chiara^1,3 (AUTHOR)

Subjects: *PRIMARY cell culture; *EPITHELIAL cell culture; *MEMBRANE transport proteins

• Source: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11454. 19p.

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A Conserved Intramolecular Ion-Pair Plays a Critical but Divergent Role in Regulation of Dimerization and Transport Function among the Monoamine Transporters.

• Authors : Chen S; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.; Huang X

Subjects: Cysteine* ; Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/genetics; Dimerization

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 04; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Rapid responses: Receptor‐like kinases directly regulate the functions of membrane transport proteins in plants.

• Authors : Li, Xiaopeng¹ (AUTHOR); Zhang, Jingjie¹ (AUTHOR); Shi, Hongyong² (AUTHOR)

Subjects: *MEMBRANE transport proteins; *RECEPTOR-like kinases; *PLANT proteins

• Source: Journal of Integrative Plant Biology. Jul2022, Vol. 64 Issue 7, p1303-1309. 7p.

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Helicobacter pylori Efflux Pumps: A Double-Edged Sword in Antibiotic Resistance and Biofilm Formation.

• Authors : Krzyżek P; Department of Microbiology, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.

Subjects: Helicobacter pylori*/Helicobacter pylori*/Helicobacter pylori*/drug effects ; Helicobacter pylori*/Helicobacter pylori*/Helicobacter pylori*/metabolism ; Helicobacter pylori*/Helicobacter pylori*/Helicobacter pylori*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 14; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity.

• Authors : Barth B; Integrated Program in Neurosciences, McGill University, Montreal, QC, Canada.; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.

Subjects: Dopamine Plasma Membrane Transport Proteins*/Dopamine Plasma Membrane Transport Proteins*/Dopamine Plasma Membrane Transport Proteins*/genetics ; Dopamine Plasma Membrane Transport Proteins*/Dopamine Plasma Membrane Transport Proteins*/Dopamine Plasma Membrane Transport Proteins*/metabolism ; Mental Disorders*/Mental Disorders*/Mental Disorders*/genetics

• Source: Scientific reports [Sci Rep] 2024 Nov 09; Vol. 14 (1), pp. 27349. Date of Electronic Publication: 2024 Nov 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.

• Authors : Ferreira LT; Laboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil.; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, United States of America.

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/pharmacology ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/genetics

• Source: PLoS pathogens [PLoS Pathog] 2024 Oct 29; Vol. 20 (10), pp. e1012627. Date of Electronic Publication: 2024 Oct 29 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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