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RBM17 Promotes the Chemoresistance of Oral Squamous Cancer Cells Through Checkpoint Kinase 1.

• Authors : Nakahara, Miyuka¹ (AUTHOR); Arai, Ryosuke² (AUTHOR); Tokuoka, Isao^2,3 (AUTHOR)

• Source: International Journal of Molecular Sciences. Apr2025, Vol. 26 Issue 7, p3127. 14p.

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Checkpoint Kinase 1 Inhibitor Combined with Low Dose Hydroxyurea Promotes ATM-Activated NF-κB-Dependent Pro-Inflammatory Chemokine Expression in Melanomas.

• Authors : Goh, Nicole Lisa Li-Ann¹ (AUTHOR); Abdul Rahim, Nur Jannah^1,2 (AUTHOR); Bhatt, Rituparna¹ (AUTHOR)

• Source: Cancers. Jun2025, Vol. 17 Issue 11, p1817. 13p.

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Checkpoint kinase 1 inhibitor + low‐dose hydroxyurea efficiently kills BRAF inhibitor‐ and immune checkpoint inhibitor‐resistant melanomas.

• Authors : Zeng, Zhen¹ (AUTHOR); Ngo, Hung Long¹ (AUTHOR); Proctor, Martina¹ (AUTHOR)

• Source: Pigment Cell & Melanoma Research. Jan2024, Vol. 37 Issue 1, p45-50. 6p.

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A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model.

• Authors : Takeda, Kenji^1,2 (AUTHOR) ; Sakai-Sakasai, Akiko¹ (AUTHOR) ; Kajinami, Kouji² (AUTHOR)

• Source: Cells (2073-4409). Dec2023, Vol. 12 Issue 24, p2838. 26p.

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Antitumor Activity of Radiation Therapy Combined with Checkpoint Kinase Inhibition in SHH/ p53 -Mutated Human Medulloblastoma.

• Authors : Kuchařová, Zuzana¹ (AUTHOR); Glasow, Annegret^1,2 (AUTHOR); Kortmann, Rolf-Dieter¹ (AUTHOR)

• Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2577. 17p.

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Predicting breast cancer prognosis based on a novel pathomics model through CHEK1 expression analysis using machine learning algorithms.

• Authors : Chen, Chen¹ (AUTHOR); Gao, Dan¹ (AUTHOR); Yue, Huan² (AUTHOR)

• Source: PLoS ONE. 5/9/2025, Vol. 20 Issue 5, p1-24. 24p.

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Small-Molecule Mitotic Inhibitors as Anticancer Agents: Discovery, Classification, Mechanisms of Action, and Clinical Trials.

• Authors : Salinas, Yazmin¹ (AUTHOR); Chauhan, Subhash C.^2,3 (AUTHOR); Bandyopadhyay, Debasish^1,3,4 (AUTHOR)

• Source: International Journal of Molecular Sciences. Apr2025, Vol. 26 Issue 7, p3279. 36p.

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Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo.

• Authors : Baran, Vladimír¹ (AUTHOR) ; Mayer, Alexandra² (AUTHOR)

• Source: International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 7, p6778. 15p.

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Checkpoint Kinase 1 Stimulates Endogenous Cardiomyocyte Renewal and Cardiac Repair by Binding to Pyruvate Kinase Isoform M2 C‐Domain and Activating Cardiac Metabolic Reprogramming in a Porcine Model of Myocardial Ischemia/Reperfusion Injury

• Authors : Tian‐Wen Wei; Tian‐Kai Shan; Hao Wang

Subjects: metabolic reprogramming; myocardial ischemia/reperfusion injury; myocardial repair

• Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)

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Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.

• Authors : Thakur V; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.; Thakur VS

Subjects: Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/antagonists & inhibitors ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; Receptor, Notch1*/Receptor, Notch1*/Receptor, Notch1*/antagonists & inhibitors

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 May 28; Vol. 44 (1), pp. 163. Date of Electronic Publication: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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