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Publication : xenobiotica

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Academic Journal

Pharmacokinetics, tissue distribution, plasma protein binding rate and excretion of sinoacutine following intravenous administration in female and male Sprague-Dawley rats.

Authors : Zhu, Liyuan¹ (AUTHOR); Mei, Jiahua^2,3 (AUTHOR); Peng, Chaorui¹ (AUTHOR)

Source: Xenobiotica. Jan2022, Vol. 52 Issue 1, p91-98. 8p.

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Academic Journal

Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir.

Authors : Greenfield, Siennah R.¹ (AUTHOR); Eng, Heather² (AUTHOR); Yang, Qingyi¹ (AUTHOR)

Source: Xenobiotica. Jan2023, Vol. 53 Issue 1, p12-24. 13p.

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Academic Journal

Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse.

Authors : Miyamoto, Maki¹ (AUTHOR); Kosugi, Yohei¹ (AUTHOR); Iwasaki, Shinji¹ (AUTHOR)

Source: Xenobiotica. Jan2021, Vol. 51 Issue 1, p51-60. 10p.

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Plasma protein binding, metabolism, reaction phenotyping and toxicokinetic studies of fenarimol after oral and intravenous administration in rats.

Authors : Karsauliya, Kajal^1,2 (AUTHOR); Sonker, Ashish Kumar^1,3 (AUTHOR); Bhateria, Manisha¹ (AUTHOR)

Source: Xenobiotica. Jan2021, Vol. 51 Issue 1, p72-81. 10p.

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Academic Journal

Protein binding of fentanyl and its metabolite nor-fentanyl in human plasma, albumin and α-1 acid glycoprotein.

Authors : Bista, Sudeep Raj^1,2 (AUTHOR) ; Haywood, Alison^1,2 (AUTHOR); Hardy, Janet² (AUTHOR)

Source: Xenobiotica. Mar2015, Vol. 45 Issue 3, p207-212. 6p.

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Academic Journal

Effect of diammonium glycyrrhizinate on pharmacokinetics of omeprazole by regulating cytochrome P450 enzymes and plasma protein binding rate.

Authors : Han, Lu¹; Wang, Rong¹; Wu, Bin¹

Source: Xenobiotica. Aug2019, Vol. 49 Issue 8, p975-980. 6p.

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Academic Journal

Kinetic determinants of hepatic clearance: Plasma protein binding and hepatic uptake.

Authors : Baker, M.^1,2 (AUTHOR) ; Parton, T.³ (AUTHOR)

Source: Xenobiotica. Oct/Nov2007, Vol. 37 Issue 10/11, p1110-1134. 25p. 4 Diagrams, 1 Chart, 10 Graphs.

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Academic Journal

Predicting successful/unsuccessful extrapolation for in vivo total clearance of model compounds with a variety of hepatic intrinsic metabolism and protein bindings in humans from pharmacokinetic data using chimeric mice with humanised liver.

Authors : Sawada, Takeshi¹ (AUTHOR) ; Yamaura, Yoshiyuki¹ (AUTHOR); Higuchi, Satonori² (AUTHOR)

Source: Xenobiotica. May2020, Vol. 50 Issue 5, p526-535. 10p.

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Academic Journal

Determination, pharmacokinetics and protein binding of a novel tissue-type plasminogen activator, pamiteplase in human plasma.

Authors : Oikawa, K.¹; Watanabe, T.¹; Miyamoto, I.²

Source: Xenobiotica. Oct2000, Vol. 30 Issue 10, p993-1003. 11p. 3 Charts, 5 Graphs.

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Academic Journal

Investigation of the prerequisites for the optimization of specific plasma protein binding as a strategy for the reduction of first-pass hepatic metabolism.

Authors : Svennebring, Andreas Mats¹ (AUTHOR)

Source: Xenobiotica. Apr2015, Vol. 45 Issue 4, p286-301. 16p.

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نتائج البحث

فلترة النتائج

Pharmacokinetics, tissue distribution, plasma protein binding rate and excretion of sinoacutine following intravenous administration in female and male Sprague-Dawley rats.

Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir.

Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse.

Plasma protein binding, metabolism, reaction phenotyping and toxicokinetic studies of fenarimol after oral and intravenous administration in rats.

Protein binding of fentanyl and its metabolite nor-fentanyl in human plasma, albumin and α-1 acid glycoprotein.

Effect of diammonium glycyrrhizinate on pharmacokinetics of omeprazole by regulating cytochrome P450 enzymes and plasma protein binding rate.

Kinetic determinants of hepatic clearance: Plasma protein binding and hepatic uptake.

Predicting successful/unsuccessful extrapolation for in vivo total clearance of model compounds with a variety of hepatic intrinsic metabolism and protein bindings in humans from pharmacokinetic data using chimeric mice with humanised liver.

Determination, pharmacokinetics and protein binding of a novel tissue-type plasminogen activator, pamiteplase in human plasma.

Investigation of the prerequisites for the optimization of specific plasma protein binding as a strategy for the reduction of first-pass hepatic metabolism.

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