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  • 1-10 ل  340 نتائج ل ""rapamycin""

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Academic Journal

mTORC1 pathway activity biases cell fate choice.

  • Authors : Wang Y; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; Papayova M

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Dictyostelium*/Dictyostelium*/Dictyostelium*/metabolism ; Dictyostelium*/Dictyostelium*/Dictyostelium*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Sep 06; Vol. 14 (1), pp. 20832. Date of Electronic Publication: 2024 Sep 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Regulation of TSC2 lysosome translocation and mitochondrial turnover by TSC2 acetylation status.

  • Authors : Marqués P; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain.; Burillo J

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Tuberous Sclerosis Complex 2 Protein*/Tuberous Sclerosis Complex 2 Protein*/Tuberous Sclerosis Complex 2 Protein*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 May 31; Vol. 14 (1), pp. 12521. Date of Electronic Publication: 2024 May 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle.

  • Authors : Ryan PJ; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.; Uranga S

Subjects: TOR Serine-Threonine Kinases* ; Autophagy*/Autophagy*/Autophagy*/physiology ; Aminopyridines*

  • Source: Scientific reports [Sci Rep] 2024 Apr 06; Vol. 14 (1), pp. 8094. Date of Electronic Publication: 2024 Apr 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation.

  • Authors : Yoshimura R; Department of Health and Nutrition, Faculty of Health Management, Nagasaki International University, 2825-7 Huis Ten Bosch Machi, Sasebo City, Nagasaki, Japan. .; Nomura S

Subjects: Glutamine*/Glutamine*/Glutamine*/administration & dosage ; Leucine*/Leucine*/Leucine*/administration & dosage ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism

  • Source: Scientific reports [Sci Rep] 2022 Sep 23; Vol. 12 (1), pp. 15870. Date of Electronic Publication: 2022 Sep 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis.

  • Authors : Rosario FJ; Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .; Gupta MB

Subjects: Gene Expression Regulation, Developmental*; Fetal Growth Retardation/Fetal Growth Retardation/Fetal Growth Retardation/*genetics ; Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Jan 22; Vol. 9 (1), pp. 246. Date of Electronic Publication: 2019 Jan 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling.

  • Authors : Kim HS; Amorepacific Research and Innovation Center, Yongin, Gyeonggi-do, 17074, Korea.; Kim HJ

Subjects: beta-Endorphin*/beta-Endorphin*/beta-Endorphin*/metabolism ; Epidermis*/Epidermis*/Epidermis*/metabolism; Humans

  • Source: Scientific reports [Sci Rep] 2023 Dec 15; Vol. 13 (1), pp. 22357. Date of Electronic Publication: 2023 Dec 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Investigating the prognostic value of mTORC1 signaling in bladder cancer via bioinformatics evaluation.

  • Authors : Yu X; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, 238 Ziyang Road, Wuhan, 430060, Hubei Province, People's Republic of China.; Li W

Subjects: Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/genetics; Humans ; Prognosis

  • Source: Scientific reports [Sci Rep] 2023 Dec 12; Vol. 13 (1), pp. 22066. Date of Electronic Publication: 2023 Dec 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer.

  • Authors : Sniegowski T; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.; Rajasekaran D

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/pathology ; Amino Acid Transport Systems, Neutral*

  • Source: Scientific reports [Sci Rep] 2023 Oct 06; Vol. 13 (1), pp. 16863. Date of Electronic Publication: 2023 Oct 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Methylglyoxal induces p53 activation and inhibits mTORC1 in human umbilical vein endothelial cells.

  • Authors : Zhang X; Department of Nephrology, Endocrinology and Rheumatology, Fifth Department of Medicine, University Hospital Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. .; Rodriguez-Niño A

Subjects: Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/*metabolism ; Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/Mechanistic Target of Rapamycin Complex 1/*antagonists & inhibitors ; Pyruvaldehyde/Pyruvaldehyde/Pyruvaldehyde/*pharmacology

  • Source: Scientific reports [Sci Rep] 2021 Apr 13; Vol. 11 (1), pp. 8004. Date of Electronic Publication: 2021 Apr 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling.

  • Authors : Xu K; Central laboratory, General Surgery, Putuo Hospital, and Interventional Cancer Institute of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, 164 Lanxi Rd, Shanghai 200062, PR China.; Chen G

Subjects: Signal Transduction*; GTP Phosphohydrolases/GTP Phosphohydrolases/GTP Phosphohydrolases/*metabolism ; Mechanistic Target of Rapamycin Complex 2/Mechanistic Target of Rapamycin Complex 2/Mechanistic Target of Rapamycin Complex 2/*metabolism

  • Source: Scientific reports [Sci Rep] 2017 Feb 08; Vol. 7, pp. 41718. Date of Electronic Publication: 2017 Feb 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  340 نتائج ل ""rapamycin""