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Academic Journal

The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer.

  • Authors : Moerland JA; Department of Pharmacology and Toxicology, Michigan State University, B430 Life Science Building, 1355 Bogue Street, East Lansing, MI, 48824, USA.; Zhang D

Subjects: Carcinogens*; Anticarcinogenic Agents/Anticarcinogenic Agents/Anticarcinogenic Agents/*pharmacology ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: Scientific reports [Sci Rep] 2020 Dec 17; Vol. 10 (1), pp. 22244. Date of Electronic Publication: 2020 Dec 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanisms of D1/D2-like dopaminergic agonist, rotigotine, on lower urinary tract function in rat model of Parkinson's disease.

  • Authors : Ouchi M; Department of Renal and Genitourinary Surgery, Graduate School of Medical Science, Hokkaido University, Kita 15 Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.; Kitta T

Subjects: Dopamine Agonists*/Dopamine Agonists*/Dopamine Agonists*/pharmacology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy; Animals

  • Source: Scientific reports [Sci Rep] 2022 Mar 16; Vol. 12 (1), pp. 4540. Date of Electronic Publication: 2022 Mar 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Selective estrogen receptor modulator lasofoxifene suppresses spondyloarthritis manifestation and affects characteristics of gut microbiota in zymosan-induced SKG mice.

  • Authors : Jeong H; Department of Internal Medicine, Soonchunhyang University Hospital, Bucheon, Republic of Korea.; Kim IY

Subjects: Arthritis, Experimental/Arthritis, Experimental/Arthritis, Experimental/*prevention & control ; Gastrointestinal Microbiome/Gastrointestinal Microbiome/Gastrointestinal Microbiome/*drug effects ; Pyrrolidines/Pyrrolidines/Pyrrolidines/*pharmacology

  • Source: Scientific reports [Sci Rep] 2021 Jun 07; Vol. 11 (1), pp. 11923. Date of Electronic Publication: 2021 Jun 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of epithelial-mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist.

  • Authors : Kobayashi Y; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi, 755-8505, Japan.; Tokuda K

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects ; Retinal Pigment Epithelium/Retinal Pigment Epithelium/Retinal Pigment Epithelium/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Jun 04; Vol. 11 (1), pp. 11842. Date of Electronic Publication: 2021 Jun 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

K 2P 2.1 (TREK-1) potassium channel activation protects against hyperoxia-induced lung injury.

  • Authors : Zyrianova T; Department of Pediatrics, University of California Los Angeles, 10833 Le Conte Ave, MDCC 12-475, Los Angeles, CA, 90095, USA.; Lopez B

Subjects: Ion Channel Gating*/Ion Channel Gating*/Ion Channel Gating*/drug effects; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*etiology ; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Dec 15; Vol. 10 (1), pp. 22011. Date of Electronic Publication: 2020 Dec 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein.

  • Authors : Watanabe H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, 862-0973, Japan. .; Bi J

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Kidney/Kidney/Kidney/*drug effects ; Orosomucoid/Orosomucoid/Orosomucoid/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Jul 10; Vol. 10 (1), pp. 11424. Date of Electronic Publication: 2020 Jul 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Understanding the metabolism of the tetralin degrader Sphingopyxis granuli strain TFA through genome-scale metabolic modelling.

  • Authors : García-Romero I; Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide, ES-41013, Seville, Spain.; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, United Kingdom.

Subjects: Energy Metabolism/Energy Metabolism/Energy Metabolism/*genetics ; Genome, Bacterial/Genome, Bacterial/Genome, Bacterial/*genetics ; Metabolic Networks and Pathways/Metabolic Networks and Pathways/Metabolic Networks and Pathways/*genetics Sphingopyxis granuli

  • Source: Scientific reports [Sci Rep] 2020 May 26; Vol. 10 (1), pp. 8651. Date of Electronic Publication: 2020 May 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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