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Academic Journal

Bitter tastants relax the mouse gallbladder smooth muscle independent of signaling through tuft cells and bitter taste receptors.

  • Authors : Keshavarz M; Institute for Anatomy and Cell Biology, German Center for Lung Research, Justus Liebig University, Giessen, Germany. .; Excellence Cluster Cardio-Pulmonary Institute, Justus Liebig University, Giessen, Germany. .

Subjects: Gallbladder*/Gallbladder*/Gallbladder*/metabolism ; Muscle, Smooth*/Muscle, Smooth*/Muscle, Smooth*/metabolism ; Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 08; Vol. 14 (1), pp. 18447. Date of Electronic Publication: 2024 Aug 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

NOX2-TRPM2 coupling promotes Zn 2+ inhibition of complex III to exacerbate ROS production in a cellular model of Parkinson's disease.

  • Authors : AlAhmad M; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, G6.44d, Garstang Building, Leeds, LS29JT, UK.; Department of Biological Sciences, College of Science, Kuwait University, Alshadadiya, PO Box 5969, 130602, Safat, Kuwait.

Subjects: Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism ; NADPH Oxidase 2*/NADPH Oxidase 2*/NADPH Oxidase 2*/metabolism ; NADPH Oxidase 2*/NADPH Oxidase 2*/NADPH Oxidase 2*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Aug 08; Vol. 14 (1), pp. 18431. Date of Electronic Publication: 2024 Aug 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.

  • Authors : Szollosi A; Department of Biochemistry, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary. .; ELKH-SE Ion Channel Research Group, Semmelweis University, Tuzolto u. 37-47, Budapest, 1094, Hungary. .

Subjects: TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/metabolism ; Sea Anemones*/Sea Anemones*/Sea Anemones*/metabolism; Animals

  • Source: Scientific reports [Sci Rep] 2023 Jul 15; Vol. 13 (1), pp. 11471. Date of Electronic Publication: 2023 Jul 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TRPM7 kinase mediates hypomagnesemia-induced seizure-related death.

  • Authors : Liu M; Cardiovascular Division, Department of Medicine, The Lillehei Heart Institute, University of Minnesota at Twin Cities, 2231 6th Street SE, CCRB 4-141, Minneapolis, MN, 55455, USA.; Liu H

Subjects: TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/genetics; Mice ; Male

  • Source: Scientific reports [Sci Rep] 2023 May 15; Vol. 13 (1), pp. 7855. Date of Electronic Publication: 2023 May 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

CBGA ameliorates inflammation and fibrosis in nephropathy.

  • Authors : Suzuki S; Center for Biomedical Research, The Queen's Medical Center, 1301 Punchbowl St., Honolulu, HI, 96813, USA. .; Fleig A

Subjects: TRPM Cation Channels* ; Ureteral Obstruction*/Ureteral Obstruction*/Ureteral Obstruction*/complications ; Ureteral Obstruction*/Ureteral Obstruction*/Ureteral Obstruction*/drug therapy

  • Source: Scientific reports [Sci Rep] 2023 Apr 18; Vol. 13 (1), pp. 6341. Date of Electronic Publication: 2023 Apr 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Influence of TRPM4 rs8104571 genotype on intracranial pressure and outcomes in African Americans with traumatic brain injury.

  • Authors : Krocker JD; Center for Translational Injury Research, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, 6431 Fannin St., MSB 5.204, Houston, TX, 77030, USA. .; Cotton ME

Subjects: Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/genetics ; Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/complications ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/genetics

  • Source: Scientific reports [Sci Rep] 2023 Apr 10; Vol. 13 (1), pp. 5815. Date of Electronic Publication: 2023 Apr 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Binding epitope for recognition of human TRPM4 channel by monoclonal antibody M4M.

  • Authors : Wei S; Calcium Signalling Laboratory, Department of Research, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.; Behn J

Subjects: Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/metabolism ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/genetics ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/metabolism

  • Source: Scientific reports [Sci Rep] 2022 Nov 15; Vol. 12 (1), pp. 19562. Date of Electronic Publication: 2022 Nov 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression.

  • Authors : Bao L; Departments of Pediatrics, The Pennsylvania State University College of Medicine, P.O. Box 850, Hershey, PA, 17033, USA.; Festa F

Subjects: Neuroblastoma*/Neuroblastoma*/Neuroblastoma*/genetics ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/genetics; Humans

  • Source: Scientific reports [Sci Rep] 2022 Nov 29; Vol. 12 (1), pp. 20544. Date of Electronic Publication: 2022 Nov 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

FAM111A is dispensable for electrolyte homeostasis in mice.

  • Authors : Ilenwabor BP; Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Schigt H

Subjects: Hyperostosis, Cortical, Congenital*/Hyperostosis, Cortical, Congenital*/Hyperostosis, Cortical, Congenital*/genetics ; Hypocalcemia*/Hypocalcemia*/Hypocalcemia*/genetics ; Serine Proteases*/Serine Proteases*/Serine Proteases*/genetics

  • Source: Scientific reports [Sci Rep] 2022 Jun 17; Vol. 12 (1), pp. 10211. Date of Electronic Publication: 2022 Jun 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1.

  • Authors : Hirschler-Laszkiewicz I; Department of Pediatrics, The Pennsylvania State University College of Medicine, P.O. Box 850, Hershey, PA, 17033, USA.; Festa F

Subjects: E2F1 Transcription Factor*/E2F1 Transcription Factor*/E2F1 Transcription Factor*/metabolism ; Forkhead Box Protein M1*/Forkhead Box Protein M1*/Forkhead Box Protein M1*/genetics ; Forkhead Box Protein M1*/Forkhead Box Protein M1*/Forkhead Box Protein M1*/metabolism

  • Source: Scientific reports [Sci Rep] 2022 Apr 15; Vol. 12 (1), pp. 6311. Date of Electronic Publication: 2022 Apr 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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