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Academic Journal

CX-5461 induces radiosensitization through modification of the DNA damage response and not inhibition of RNA polymerase I.

  • Authors : Lehman SL; Radiation Oncology Branch, National Cancer Institute, 10 Center Drive-MSC 1002, Building 10, B3B69B, Bethesda, MD, 20892, USA.; Schwartz KR

Subjects: Benzothiazoles*/Benzothiazoles*/Benzothiazoles*/pharmacology ; Naphthyridines*/Naphthyridines*/Naphthyridines*/pharmacology ; RNA Polymerase I*/RNA Polymerase I*/RNA Polymerase I*/antagonists & inhibitors

  • Source: Scientific reports [Sci Rep] 2022 Mar 08; Vol. 12 (1), pp. 4059. Date of Electronic Publication: 2022 Mar 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma.

  • Authors : Fernández-Parejo N; Centro de Investigación del Cáncer and Instituto de Biología Molecular del Cáncer, CSIC and Universidad de Salamanca, 37007, Salamanca, Spain.; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain.

Subjects: Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/pathology ; Head and Neck Neoplasms* ; Mouth Neoplasms*/Mouth Neoplasms*/Mouth Neoplasms*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4060. Date of Electronic Publication: 2024 Feb 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription.

  • Authors : Katagiri N; Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennnoudai, Tsukuba 305-8577, Japan.; Kuroda T

Subjects: Transcription, Genetic*; Autophagy/Autophagy/Autophagy/*genetics ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2015 Mar 10; Vol. 5, pp. 8903. Date of Electronic Publication: 2015 Mar 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Depletion of ribosomal protein S19 causes a reduction of rRNA synthesis.

  • Authors : Juli G; Department of Biology, University of Rome Tor Vergata, Roma, Italy.; Gismondi A

Subjects: Anemia, Diamond-Blackfan/Anemia, Diamond-Blackfan/Anemia, Diamond-Blackfan/*genetics ; RNA Polymerase I/RNA Polymerase I/RNA Polymerase I/*metabolism ; RNA, Ribosomal/RNA, Ribosomal/RNA, Ribosomal/*metabolism

  • Source: Scientific reports [Sci Rep] 2016 Oct 13; Vol. 6, pp. 35026. Date of Electronic Publication: 2016 Oct 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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