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Academic Journal

Chronic BDNF simultaneously inhibits and unmasks superficial dorsal horn neuronal activity.

  • Authors : Alles SRA; Department of Anesthesiology & Critical Care Medicine, University of New Mexico Health Sciences Center, MSC 10-6000, 2211 Lomas Blvd. NE, ACM 200, Albuquerque, NM, 87106, USA. .; Neuroscience and Mental Health Institute & Department of Pharmacology, University of Alberta, Edmonton, AB, Canada. .

Subjects: Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/*pharmacology ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*physiology; 1-Octanol/1-Octanol/1-Octanol/pharmacology

  • Source: Scientific reports [Sci Rep] 2021 Jan 26; Vol. 11 (1), pp. 2249. Date of Electronic Publication: 2021 Jan 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibiting the LPS-induced enhancement of mEPSC frequency in superficial dorsal horn neurons may serve as an electrophysiological model for alleviating pain.

  • Authors : Yang CT; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Leisure Industry and Health Promotion, National Ilan University, Yilan, Taiwan.

Subjects: Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/chemically induced ; Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/metabolism ; Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/pathology

  • Source: Scientific reports [Sci Rep] 2019 Nov 05; Vol. 9 (1), pp. 16032. Date of Electronic Publication: 2019 Nov 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphorylated Histone 3 at Serine 10 Identifies Activated Spinal Neurons and Contributes to the Development of Tissue Injury-Associated Pain.

  • Authors : Torres-Pérez JV; Nociception Group, Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, SW10 9NH, United Kingdom.; Sántha P

Subjects: Nociception* ; Protein Processing, Post-Translational*; Histones/Histones/Histones/*metabolism

  • Source: Scientific reports [Sci Rep] 2017 Jan 25; Vol. 7, pp. 41221. Date of Electronic Publication: 2017 Jan 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord.

  • Authors : Davis OC; School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.; Dickie AC

Subjects: Nociceptors* ; Spinal Cord*/Spinal Cord*/Spinal Cord*/physiology; Animals

  • Source: Scientific reports [Sci Rep] 2023 Jul 18; Vol. 13 (1), pp. 11561. Date of Electronic Publication: 2023 Jul 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tranexamic acid evokes pain by modulating neuronal excitability in the spinal dorsal horn.

  • Authors : Ohashi N; Division of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi Dori, Chuo-Ku, Niigata City, 951-8510 Japan.; Sasaki M

Subjects: Pain/Pain/Pain/*chemically induced ; Pain/Pain/Pain/*physiopathology ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*pathology

  • Source: Scientific reports [Sci Rep] 2015 Aug 21; Vol. 5, pp. 13458. Date of Electronic Publication: 2015 Aug 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tet1-dependent epigenetic modification of BDNF expression in dorsal horn neurons mediates neuropathic pain in rats.

  • Authors : Hsieh MC; Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei, Taiwan.

Subjects: Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/*genetics ; Dioxygenases/Dioxygenases/Dioxygenases/*genetics ; Neuralgia/Neuralgia/Neuralgia/*genetics

  • Source: Scientific reports [Sci Rep] 2016 Nov 18; Vol. 6, pp. 37411. Date of Electronic Publication: 2016 Nov 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain.

  • Authors : Imlach WL; The University of Sydney, Discipline of Pharmacology, Sydney, NSW 2006, Australia.; Bhola RF

Subjects: Synaptic Transmission*; Neuralgia/Neuralgia/Neuralgia/*metabolism ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*metabolism

  • Source: Scientific reports [Sci Rep] 2016 Nov 14; Vol. 6, pp. 37104. Date of Electronic Publication: 2016 Nov 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intravenous administration of lidocaine directly acts on spinal dorsal horn and produces analgesic effect: An in vivo patch-clamp analysis.

  • Authors : Kurabe M; Division of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi Dori, Chuo-Ku, Niigata City, 951-8510 Japan.; Furue H

Subjects: Analgesics/Analgesics/Analgesics/*pharmacology ; Lidocaine/Lidocaine/Lidocaine/*pharmacology ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*drug effects

  • Source: Scientific reports [Sci Rep] 2016 May 18; Vol. 6, pp. 26253. Date of Electronic Publication: 2016 May 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch.

  • Authors : Jiang GY; 1] Key Laboratory of Arrhythmias, Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai 200120, China [2] Department of Anatomy and Neurobiology, Collaborative Innovation Center for Brain Science, Tongji University School of Medicine, Shanghai 200092, China [3] School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.; Dai MH

Subjects: Histamine/Histamine/Histamine/*pharmacology ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*physiology ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*metabolism

  • Source: Scientific reports [Sci Rep] 2015 Aug 07; Vol. 5, pp. 12787. Date of Electronic Publication: 2015 Aug 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons.

  • Authors : Das Gupta RR; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 1-5/10, 8090, Zurich, Switzerland.

Subjects: Protein Biosynthesis*; Neuropeptides/Neuropeptides/Neuropeptides/*genetics ; Posterior Horn Cells/Posterior Horn Cells/Posterior Horn Cells/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Mar 04; Vol. 11 (1), pp. 5232. Date of Electronic Publication: 2021 Mar 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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