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  • 1-10 ل  23 نتائج ل ""Cytochrome P-450 CYP1A2""
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Academic Journal

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients.

  • Authors : Fekete F; Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok 2, Budapest, 1117, Hungary.; Doctoral School of Biology and Institute of Biology, Eötvös Loránd University, Pázmány Péter Sétány 1/A, Budapest, 1117, Hungary.

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/metabolism ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/adverse effects

  • Source: Scientific reports [Sci Rep] 2023 Oct 28; Vol. 13 (1), pp. 18507. Date of Electronic Publication: 2023 Oct 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

In silico screening and analysis of nonsynonymous SNPs in human CYP1A2 to assess possible associations with pathogenicity and cancer susceptibility.

  • Authors : Navapour L; Biophysics and Computational Biology Laboratory (BCBL), Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran.; Mogharrab N

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/chemistry ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics ; Genetic Predisposition to Disease*

  • Source: Scientific reports [Sci Rep] 2021 Mar 02; Vol. 11 (1), pp. 4977. Date of Electronic Publication: 2021 Mar 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia.

  • Authors : Menus Á; Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa 6, 1082, Budapest, Hungary.; Kiss Á

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*adverse effects ; Clozapine/Clozapine/Clozapine/*adverse effects ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Dec 04; Vol. 10 (1), pp. 21283. Date of Electronic Publication: 2020 Dec 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing.

  • Authors : Tilleman L; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.; Rubben K

Subjects: Nanopore Sequencing*; Humans ; Haplotypes

  • Source: Scientific reports [Sci Rep] 2022 Oct 22; Vol. 12 (1), pp. 17734. Date of Electronic Publication: 2022 Oct 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion.

  • Authors : Schurink IJ; Division of Hepatopancreatobiliary Surgery, Department of Surgery, Erasmus MC Transplant Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; de Haan JE

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*genetics ; Liver/Liver/Liver/*physiology ; Liver Transplantation/Liver Transplantation/Liver Transplantation/*methods

  • Source: Scientific reports [Sci Rep] 2021 Dec 06; Vol. 11 (1), pp. 23444. Date of Electronic Publication: 2021 Dec 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Heterologous expression of high-activity cytochrome P450 in mammalian cells.

  • Authors : Kumondai M; Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba Aramaki, Aoba-ku, Sendai, 980-8578, Japan.; Hishinuma E

Subjects: Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*genetics ; Genetic Engineering/Genetic Engineering/Genetic Engineering/*methods ; Recombinant Proteins/Recombinant Proteins/Recombinant Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14193. Date of Electronic Publication: 2020 Aug 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel naphthalimide that selectively targets breast cancer via the arylhydrocarbon receptor pathway.

  • Authors : Gilbert J; Experimental Therapeutics Group, Department of Medical Oncology, Calvary Mater Newcastle Hospital, Edith Street, Waratah, NSW, 2298, Australia.; De Iuliis GN

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Naphthalimides/Naphthalimides/Naphthalimides/*pharmacology ; Receptors, Aryl Hydrocarbon/Receptors, Aryl Hydrocarbon/Receptors, Aryl Hydrocarbon/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Aug 19; Vol. 10 (1), pp. 13978. Date of Electronic Publication: 2020 Aug 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Response differences of HepG2 and Primary Mouse Hepatocytes to morphological changes in electrospun PCL scaffolds.

  • Authors : Bate TSR; Institute for Bioengineering, School of Engineering, University of Edinburgh, Edinburgh, UK.; Gadd VL

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*genetics ; Liver/Liver/Liver/*metabolism ; Liver Diseases/Liver Diseases/Liver Diseases/*therapy

  • Source: Scientific reports [Sci Rep] 2021 Feb 04; Vol. 11 (1), pp. 3059. Date of Electronic Publication: 2021 Feb 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Translational control of enzyme scavenger expression with toxin-induced micro RNA switches.

  • Authors : Pollak NM; Genecology Research Centre, University of the Sunshine Coast, Sippy Downs, QLD, Australia. .; School of Science, Technology, and Engineering, University of the Sunshine Coast, Sippy Downs, QLD, Australia. .

Subjects: Enzymes/Enzymes/Enzymes/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics ; Protein Biosynthesis/Protein Biosynthesis/Protein Biosynthesis/*genetics

  • Source: Scientific reports [Sci Rep] 2021 Jan 28; Vol. 11 (1), pp. 2462. Date of Electronic Publication: 2021 Jan 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells.

  • Authors : Heintze T; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University Tuebingen, Tuebingen, Germany.

Subjects: CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*genetics ; Cytochrome-B(5) Reductase/Cytochrome-B(5) Reductase/Cytochrome-B(5) Reductase/*genetics

  • Source: Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 1000. Date of Electronic Publication: 2021 Jan 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  23 نتائج ل ""Cytochrome P-450 CYP1A2""