نتائج البحث

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.

• Authors : Ferreira LT; Laboratory of Tropical Diseases-Prof. Dr. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil.; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, United States of America.

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/pharmacology ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/genetics

• Source: PLoS pathogens [PLoS Pathog] 2024 Oct 29; Vol. 20 (10), pp. e1012627. Date of Electronic Publication: 2024 Oct 29 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.

• Authors : Waltmann A; Division of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States.; Balthazar JT

Subjects: Gonorrhea*/Gonorrhea*/Gonorrhea*/microbiology ; Neisseria gonorrhoeae*/Neisseria gonorrhoeae*/Neisseria gonorrhoeae*/genetics ; Neisseria gonorrhoeae*/Neisseria gonorrhoeae*/Neisseria gonorrhoeae*/pathogenicity

• Source: PLoS pathogens [PLoS Pathog] 2024 Sep 25; Vol. 20 (9), pp. e1012578. Date of Electronic Publication: 2024 Sep 25 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

A component of the Xanthomonadaceae type IV secretion system combines a VirB7 motif with a N0 domain found in outer membrane transport proteins.

• Authors : Souza DP; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.; Andrade MO

Subjects: Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/*chemistry ; Membrane Transport Proteins/Membrane Transport Proteins/Membrane Transport Proteins/*chemistry ; Xanthomonas/Xanthomonas/Xanthomonas/*chemistry

• Source: PLoS pathogens [PLoS Pathog] 2011 May; Vol. 7 (5), pp. e1002031. Date of Electronic Publication: 2011 May 12.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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The protein kinase Ire1 has a Hac1-independent essential role in iron uptake and virulence of Candida albicans.

• Authors : Ramírez-Zavala B; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.; Krüger I

Subjects: Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/*metabolism ; Candida albicans/Candida albicans/Candida albicans/*metabolism ; Candidiasis/Candidiasis/Candidiasis/*microbiology

• Source: PLoS pathogens [PLoS Pathog] 2022 Feb 02; Vol. 18 (2), pp. e1010283. Date of Electronic Publication: 2022 Feb 02 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

ATM1, an essential conserved transporter in Apicomplexa, bridges mitochondrial and cytosolic [Fe-S] biogenesis.

• Authors : Shrivastava, Deepti; Abboud, Ernest; Ramchandra, Jadhav Prasad

Subjects: TOXOPLASMA gondii; ATP-binding cassette transporters; MITOCHONDRIAL proteins

• Source: PLoS Pathogens; 9/30/2024, Vol. 20 Issue 9, p1-44, 44p

تفاصيل العنوان

The extracellular loop of the membrane permease VraG interacts with GraS to sense cationic antimicrobial peptides in Staphylococcus aureus.

• Authors : Cho J; Department of Microbiology and Immunology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, United States of America.; Costa SK

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*metabolism ; Membrane Transport Proteins/Membrane Transport Proteins/Membrane Transport Proteins/*drug effects

• Source: PLoS pathogens [PLoS Pathog] 2021 Mar 01; Vol. 17 (3), pp. e1009338. Date of Electronic Publication: 2021 Mar 01 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

A Pseudomonas aeruginosa type VI secretion system regulated by CueR facilitates copper acquisition.

• Authors : Han, Yuying¹ (AUTHOR); Wang, Tietao¹ (AUTHOR); Chen, Gukui¹ (AUTHOR)

• Source: PLoS Pathogens. 12/2/2019, Vol. 15 Issue 12, p1-25. 25p.

تفاصيل العنوان

An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion.

• Authors : Thornton LB; Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America.; Teehan P

Subjects: Endosomes*/Endosomes*/Endosomes*/metabolism ; Endosomes*/Endosomes*/Endosomes*/parasitology ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism

• Source: PLoS pathogens [PLoS Pathog] 2019 Jun 06; Vol. 15 (6), pp. e1007775. Date of Electronic Publication: 2019 Jun 06 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance.

• Authors : McNeil HE; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.; Alav I

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Drug Resistance, Bacterial/Drug Resistance, Bacterial/Drug Resistance, Bacterial/*drug effects ; Membrane Transport Proteins/Membrane Transport Proteins/Membrane Transport Proteins/*drug effects

• Source: PLoS pathogens [PLoS Pathog] 2019 Dec 26; Vol. 15 (12), pp. e1008101. Date of Electronic Publication: 2019 Dec 26 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

A component of the Xanthomonadaceae type IV secretion system combines a VirB7 motif with a N0 domain found in outer membrane transport proteins.

• Authors : Diorge P Souza; Maxuel O Andrade; Cristina E Alvarez-Martinez

Subjects: Immunologic diseases. Allergy; RC581-607; Biology (General)

• Source: PLoS Pathogens, Vol 7, Iss 5, p e1002031 (2011)

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