نتائج البحث

Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.

• Authors : Nabukhotna, Kateryna¹ (AUTHOR); Kordus, Shannon L.² (AUTHOR); Shupe, John A.² (AUTHOR)

• Source: PLoS Pathogens. 9/19/2024, Vol. 20 Issue 9, p1-27. 27p.

تفاصيل العنوان

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.

• Authors : Nerber, Hailee N.¹ (AUTHOR); Baloh, Marko¹ (AUTHOR); Brehm, Joshua N.¹ (AUTHOR)

• Source: PLoS Pathogens. 8/30/2024, Vol. 20 Issue 8, p1-30. 30p.

تفاصيل العنوان

An intact S-layer is advantageous to Clostridioides difficile within the host.

• Authors : Ormsby, Michael J.¹ (AUTHOR); Vaz, Filipa¹ (AUTHOR); Kirk, Joseph A.² (AUTHOR)

• Source: PLoS Pathogens. 6/29/2023, Vol. 18 Issue 6, p1-26. 26p.

تفاصيل العنوان

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

• Authors : Marini E; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.; Olivença C

Subjects: Peptide Hydrolases*/Peptide Hydrolases*/Peptide Hydrolases*/metabolism ; Clostridioides difficile*/Clostridioides difficile*/Clostridioides difficile*/genetics ; Clostridioides difficile*/Clostridioides difficile*/Clostridioides difficile*/metabolism

• Source: PLoS pathogens [PLoS Pathog] 2023 Nov 13; Vol. 19 (11), pp. e1011741. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Food for thought—The link between Clostridioides difficile metabolism and pathogenesis.

• Authors : Marshall, Andrew¹ (AUTHOR) ; McGrath, John W.¹ (AUTHOR); Graham, Robert¹ (AUTHOR)

• Source: PLoS Pathogens. 1/5/2023, Vol. 18 Issue 1, p1-20. 20p.

تفاصيل العنوان

Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile.

• Authors : Reyes Ruiz, Leila M.¹ (AUTHOR); King, Kathleen A.¹ (AUTHOR); Agosto-Burgos, Christian² (AUTHOR)

• Source: PLoS Pathogens. 7/5/2022, Vol. 18 Issue 7, p1-23. 23p.

تفاصيل العنوان

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.

• Authors : Peritore-Galve, F. Christopher^1,2 (AUTHOR); Shupe, John A.^1,2 (AUTHOR); Cave, Rory J.³ (AUTHOR)

• Source: PLoS Pathogens. 2/17/2022, Vol. 18 Issue 2, p1-19. 19p.

تفاصيل العنوان

Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease.

• Authors : Larabee JL; Department of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.; Doyle DA

Subjects: Clostridioides difficile*/Clostridioides difficile*/Clostridioides difficile*/genetics ; Bacterial Toxins*/Bacterial Toxins*/Bacterial Toxins*/metabolism; Humans

• Source: PLoS pathogens [PLoS Pathog] 2023 Mar 27; Vol. 19 (3), pp. e1011272. Date of Electronic Publication: 2023 Mar 27 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.

• Authors : Kateryna Nabukhotna; Shannon L Kordus; John A Shupe

Subjects: Immunologic diseases. Allergy; RC581-607; Biology (General)

• Source: PLoS Pathogens, Vol 20, Iss 9, p e1012568 (2024)

تفاصيل العنوان

A short chain fatty acid–centric view of Clostridioides difficile pathogenesis.

• Authors : Gregory, Anna L.^1,2,3 (AUTHOR); Pensinger, Daniel A.^1,2 (AUTHOR); Hryckowian, Andrew J.^1,2 (AUTHOR)

• Source: PLoS Pathogens. 10/21/2021, Vol. 17 Issue 10, p1-15. 15p.

تفاصيل العنوان