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  • 1-10 ل  88 نتائج ل ""Cyclin-Dependent Kinase 9""

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Academic Journal

Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding.

  • Authors : Asamitsu K; Department of Neurocognitive Science, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan.; Hirokawa T

Subjects: Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/metabolism ; HIV-1*/HIV-1*/HIV-1*/genetics; Positive Transcriptional Elongation Factor B/Positive Transcriptional Elongation Factor B/Positive Transcriptional Elongation Factor B/metabolism

  • Source: PloS one [PLoS One] 2022 Nov 15; Vol. 17 (11), pp. e0277024. Date of Electronic Publication: 2022 Nov 15 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis.

  • Authors : Wang K; MRC Centre for Immune Regulation, Institute of Biomedical Research, Birmingham University Medical School, Birmingham, United Kingdom.; Hampson P

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*metabolism ; Neutrophils/Neutrophils/Neutrophils/*cytology

  • Source: PloS one [PLoS One] 2012; Vol. 7 (1), pp. e30128. Date of Electronic Publication: 2012 Jan 19.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor.

  • Authors : Lim SL; Cedars Sinai Medical Center, Los Angeles, California, United States of America.; Xu L

Subjects: Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*antagonists & inhibitors ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*pharmacology ; Proteins/Proteins/Proteins/*metabolism

  • Source: PloS one [PLoS One] 2020 Jun 19; Vol. 15 (6), pp. e0232068. Date of Electronic Publication: 2020 Jun 19 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Targeting of CDK9 with indirubin 3'-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice.

  • Authors : Medina-Moreno S; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.; Dowling TC

Subjects: Anti-HIV Agents/Anti-HIV Agents/Anti-HIV Agents/*pharmacology ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*antagonists & inhibitors ; HIV-1/HIV-1/HIV-1/*isolation & purification

  • Source: PloS one [PLoS One] 2017 Aug 17; Vol. 12 (8), pp. e0183425. Date of Electronic Publication: 2017 Aug 17 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis

Subjects: Cyclin T1; Neutrophils; Immunology

  • Source: PLoS ONEPLoS ONE, Vol 7, Iss 1, p e30128 (2012)

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Academic Journal

MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding.

  • Authors : Asamitsu K; Department of Molecular and Cellular Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.; Hirokawa T

Subjects: Molecular Dynamics Simulation*; Cyclin T/Cyclin T/Cyclin T/*chemistry ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*chemistry

  • Source: PloS one [PLoS One] 2017 Feb 08; Vol. 12 (2), pp. e0171727. Date of Electronic Publication: 2017 Feb 08 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

P-TEFb Kinase Activity Is Essential for Global Transcription, Resumption of Meiosis and Embryonic Genome Activation in Pig.

  • Authors : Oqani RK; Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University, Daejeon, 305-764, Republic of Korea.; Lin T

Subjects: Transcription, Genetic*; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*genetics ; Oocytes/Oocytes/Oocytes/*metabolism

  • Source: PloS one [PLoS One] 2016 Mar 24; Vol. 11 (3), pp. e0152254. Date of Electronic Publication: 2016 Mar 24 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition.

  • Authors : Albert TK; Institute of Molecular Tumor Biology (IMTB), Faculty of Medicine, University Muenster, 48149, Muenster, Germany.; Antrecht C

Subjects: Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*metabolism ; Positive Transcriptional Elongation Factor B/Positive Transcriptional Elongation Factor B/Positive Transcriptional Elongation Factor B/*metabolism ; Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/*metabolism

  • Source: PloS one [PLoS One] 2016 Jan 08; Vol. 11 (1), pp. e0146648. Date of Electronic Publication: 2016 Jan 08 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

MiR-191 Regulates Primary Human Fibroblast Proliferation and Directly Targets Multiple Oncogenes.

  • Authors : Polioudakis D; Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas, United States of America.; Abell NS

Subjects: Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*genetics ; Fibroblasts/Fibroblasts/Fibroblasts/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics

  • Source: PloS one [PLoS One] 2015 May 20; Vol. 10 (5), pp. e0126535. Date of Electronic Publication: 2015 May 20 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study.

  • Authors : Jin HX; Key Laboratory of Applied Marine Biotechnology Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, China.; Go ML

Subjects: Cyclin T/Cyclin T/Cyclin T/*metabolism ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*metabolism ; HIV-1/HIV-1/HIV-1/*metabolism

  • Source: PloS one [PLoS One] 2015 Apr 24; Vol. 10 (4), pp. e0124673. Date of Electronic Publication: 2015 Apr 24 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  88 نتائج ل ""Cyclin-Dependent Kinase 9""