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  • 1-10 ل  176 نتائج ل ""Class I Phosphatidylinositol 3-Kinases""

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Academic Journal

Development of an in vivo syngeneic mouse transplant model of invasive intestinal adenocarcinoma driven by endogenous expression of Pik3caH1047R and Apc loss.

  • Authors : de Las Heras F; Department of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/metabolism ; Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/genetics

  • Source: PloS one [PLoS One] 2024 Aug 02; Vol. 19 (8), pp. e0308051. Date of Electronic Publication: 2024 Aug 02 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay.

  • Authors : Thao DT; Center for Genetic Consultation and Cancer Screening, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam.; University of Science and Technology of Hanoi, Cau Giay, Hanoi, Vietnam.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/blood

  • Source: PloS one [PLoS One] 2024 Aug 28; Vol. 19 (8), pp. e0309209. Date of Electronic Publication: 2024 Aug 28 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA regulates development of diabetes retinopathy through the PI3K/Akt/mTOR pathway.

  • Authors : Guan R; Ophthalmology Department, Qinghai Provincial People's Hospital, Xining, Qinghai Province, China.; Kang Z

Subjects: Retinal Diseases* ; Diabetes Mellitus*; Humans

  • Source: PloS one [PLoS One] 2024 Jan 09; Vol. 19 (1), pp. e0295813. Date of Electronic Publication: 2024 Jan 09 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth.

  • Authors : Bäumer N; Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany.; Rehkämper J

Subjects: Cetuximab/Cetuximab/Cetuximab/*therapeutic use ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*genetics

  • Source: PloS one [PLoS One] 2018 Jul 12; Vol. 13 (7), pp. e0200163. Date of Electronic Publication: 2018 Jul 12 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations.

  • Authors : Blesinger H; Institute of Anatomy and Cell Biology, University Medical School Göttingen, UMG, Göttingen, Germany.; Kaulfuß S

Subjects: Mutation*; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*genetics ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*metabolism

  • Source: PloS one [PLoS One] 2018 Jul 09; Vol. 13 (7), pp. e0200343. Date of Electronic Publication: 2018 Jul 09 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition.

  • Authors : McNeill RS; Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America.; Stroobant EE

Subjects: Mutation, Missense*; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*genetics

  • Source: PloS one [PLoS One] 2018 Jul 05; Vol. 13 (7), pp. e0200014. Date of Electronic Publication: 2018 Jul 05 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer.

  • Authors : Adimonye A; Barts Cancer Institute, Centre for Molecular Oncology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Stankiewicz E

Subjects: DNA Copy Number Variations*; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*genetics ; Penile Neoplasms/Penile Neoplasms/Penile Neoplasms/*genetics

  • Source: PloS one [PLoS One] 2018 Jun 14; Vol. 13 (6), pp. e0198905. Date of Electronic Publication: 2018 Jun 14 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA mutations and their impact on survival outcomes of patients with endometrial cancer: A systematic review and meta-analysis.

  • Authors : Bredin HK; Department of Clinical Science, Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/genetics ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/pathology

  • Source: PloS one [PLoS One] 2023 Mar 21; Vol. 18 (3), pp. e0283203. Date of Electronic Publication: 2023 Mar 21 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models.

Subjects: Gene Expression Regulation, Neoplastic*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors

  • Source: PloS one [PLoS One] 2017 Aug 11; Vol. 12 (8), pp. e0182852. Date of Electronic Publication: 2017 Aug 11 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PIK3CA mutations in breast cancer: A Tunisian series.

  • Authors : Ben Rekaya M; Faculty of Medicine of Tunis, UR17ES15, University Tunis El Manar, Tunis, Tunisia.; Sassi F

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology; Female

  • Source: PloS one [PLoS One] 2023 May 17; Vol. 18 (5), pp. e0285413. Date of Electronic Publication: 2023 May 17 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  176 نتائج ل ""Class I Phosphatidylinositol 3-Kinases""