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Academic Journal

Perturbation of the Dimer Interface of Triosephosphate Isomerase and its Effect on Trypanosoma cruzi

Subjects: Models, Molecular; 0301 basic medicine; Protein Conformation

  • Source: PLoS Negl Trop DisArticles publicats en revistes (Química Inorgànica i Orgànica)Dipòsit Digital de la UBUniversidad de BarcelonaRecercat. Dipósit de la Recerca de

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Academic Journal

A kernel for open source drug discovery in tropical diseases.

  • Authors : Ortí L; Structural Genomics Unit, Bioinformatics and Genomics Department, Centro de Investigación Príncipe Felipe, Valencia, Spain.; Carbajo RJ

Subjects: Software*; Antiparasitic Agents/Antiparasitic Agents/Antiparasitic Agents/*chemistry ; Antiparasitic Agents/Antiparasitic Agents/Antiparasitic Agents/*pharmacology

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2009; Vol. 3 (4), pp. e418. Date of Electronic Publication: 2009 Apr 21.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.

  • Authors : Dvorák J; Sandler Center for Basic Research in Parasitic Diseases, California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, United States of America. ; Mashiyama ST

Subjects: Cathepsin L/Cathepsin L/Cathepsin L/*isolation & purification ; Cathepsin L/Cathepsin L/Cathepsin L/*metabolism ; Schistosoma mansoni/Schistosoma mansoni/Schistosoma mansoni/*enzymology

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2009 Jun 02; Vol. 3 (6), pp. e449. Date of Electronic Publication: 2009 Jun 02.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

An "in-depth" description of the small non-coding RNA population of Schistosoma japonicum schistosomulum.

  • Authors : Wang Z; Institute for Infectious Diseases and Vaccine Development, Tongji University School of Medicine, Shanghai, China.; Xue X

Subjects: MicroRNAs/MicroRNAs/MicroRNAs/*genetics ; RNA, Helminth/RNA, Helminth/RNA, Helminth/*genetics ; Schistosoma japonicum/Schistosoma japonicum/Schistosoma japonicum/*genetics

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 Feb 09; Vol. 4 (2), pp. e596. Date of Electronic Publication: 2010 Feb 09.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.

  • Authors : Chen CK; Department of Pharmaceutical Chemistry, University of California, San Francisco, California, United States of America.; Leung SS

Subjects: Antifungal Agents/Antifungal Agents/Antifungal Agents/*chemistry ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry ; Fluconazole/Fluconazole/Fluconazole/*chemistry

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 Apr 06; Vol. 4 (4), pp. e651. Date of Electronic Publication: 2010 Apr 06.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Computational identification of uncharacterized cruzain binding sites.

  • Authors : Durrant JD; Biomedical Sciences Program, University of California San Diego, La Jolla, California, United States of America. ; Keränen H

Subjects: Computational Biology/Computational Biology/Computational Biology/*methods ; Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*genetics ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*antagonists & inhibitors

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 May 11; Vol. 4 (5), pp. e676. Date of Electronic Publication: 2010 May 11.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei.

  • Authors : Kerr ID; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America.; Wu P

Subjects: Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*chemistry ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*chemistry; Binding Sites

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 Jun 08; Vol. 4 (6), pp. e701. Date of Electronic Publication: 2010 Jun 08.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Structural optimization and de novo design of dengue virus entry inhibitory peptides.

  • Authors : Costin JM; Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America.; Jenwitheesuk E

Subjects: Computational Biology/Computational Biology/Computational Biology/*methods ; Dengue Virus/Dengue Virus/Dengue Virus/*physiology ; Peptides/Peptides/Peptides/*pharmacology

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 Jun 22; Vol. 4 (6), pp. e721. Date of Electronic Publication: 2010 Jun 22.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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