Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Nov 29; Vol. 15 (11), pp. e0009991. Date of Electronic Publication: 2021 Nov 29 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica

Authors : Corvo, Ileana; O'Donoghue, Anthony J; Pastro, Lucía

Subjects: Biochemistry and Cell Biology; Biological Sciences; Amino Acid Substitution

Source: PLOS Neglected Tropical Diseases. 7(7)

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

Authors : Chen, Yen Ting; Brinen, Linda S; Kerr, Iain D

Subjects: Animals; Mice; Inbred C3H

Source: PLoS neglected tropical diseases. 4(9)

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.

Authors : Amaral PA; Université de Rennes 1, Equipe Chimie organique et interfaces (CORINT), UMR 6226 Sciences Chimiques de Rennes, Rennes, France.; Autheman D

Subjects: Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*antagonists & inhibitors ; Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*chemistry ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemistry

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Oct 29; Vol. 12 (10), pp. e0006853. Date of Electronic Publication: 2018 Oct 29 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target

Authors : Rob Leurs; Norbert Müller; Stefan Kunz

Subjects: Giardiasis; 0301 basic medicine; Phosphodiesterase Inhibitors

Source: PLoS Negl Trop DisPLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005891 (2017)Kunz, Stefan; Balmer, Vreni; Sterk, Geert Jan; Pollastri, Michael P;

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.

Authors : Doleželová E; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská, České Budějovice, Czech Republic.; Terán D

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Metabolic Networks and Pathways/Metabolic Networks and Pathways/Metabolic Networks and Pathways/*drug effects ; Purinones/Purinones/Purinones/*metabolism

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Feb 26; Vol. 12 (2), pp. e0006301. Date of Electronic Publication: 2018 Feb 26 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.

Authors : Torini JR; Laboratório de Biologia Estrutural, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.; Brandão-Neto J

Subjects: Models, Molecular*; Adenosine/Adenosine/Adenosine/*metabolism ; Purine-Nucleoside Phosphorylase/Purine-Nucleoside Phosphorylase/Purine-Nucleoside Phosphorylase/*chemistry

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Dec 09; Vol. 10 (12), pp. e0005178. Date of Electronic Publication: 2016 Dec 09 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia.

Authors : Hennessey KM; Department of Biology, University of Washington, Seattle, Washington, United States of America.; Smith TR

Subjects: Antiprotozoal Agents/Antiprotozoal Agents/Antiprotozoal Agents/*pharmacology ; Giardia lamblia/Giardia lamblia/Giardia lamblia/*enzymology ; Giardiasis/Giardiasis/Giardiasis/*parasitology

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Nov 02; Vol. 10 (11), pp. e0005107. Date of Electronic Publication: 2016 Nov 02 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.

Authors : Fajtová P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic; First Faculty of Medicine, Charles University, Prague, Czech Republic.

Subjects: Models, Molecular*; Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/*physiology ; Recombinant Proteins/Recombinant Proteins/Recombinant Proteins/*metabolism

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2015 Jun 03; Vol. 9 (6), pp. e0003827. Date of Electronic Publication: 2015 Jun 03 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

نتائج البحث

فلترة النتائج

Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.

Identification of enzymes that have helminth-specific active sites and are required for Rhodoquinone-dependent metabolism as targets for new anthelmintics.

Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.

The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target

Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.

Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.

Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia.

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.

اتصل بنا

اتبع