نتائج البحث

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.

• Authors : Rajani, Rikesh M.¹ (AUTHOR) ; Ellingford, Robert¹ (AUTHOR); Hellmuth, Mariam¹ (AUTHOR)

• Source: PLoS Biology. 7/23/2024, Vol. 22 Issue 7, p1-30. 30p.

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Amyloid accelerator polyphosphate fits as the mystery density in α-synuclein fibrils.

• Authors : Huettemann P; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America.; Mahadevan P

Subjects: Polyphosphates*/Polyphosphates*/Polyphosphates*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry

• Source: PLoS biology [PLoS Biol] 2024 Oct 31; Vol. 22 (10), pp. e3002650. Date of Electronic Publication: 2024 Oct 31 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.

• Authors : Zeng W; Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.; Li C

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Autophagy*/Autophagy*/Autophagy*/physiology ; Optogenetics*/Optogenetics*/Optogenetics*/methods

• Source: PLoS biology [PLoS Biol] 2024 Apr 23; Vol. 22 (4), pp. e3002591. Date of Electronic Publication: 2024 Apr 23 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype.

• Authors : Lam, Virginie^1,2 (AUTHOR); Takechi, Ryusuke^1,2 (AUTHOR); Hackett, Mark J.^1,3 (AUTHOR)

• Source: PLoS Biology. 9/14/2021, Vol. 19 Issue 9, p1-26. 26p. 3 Color Photographs, 2 Black and White Photographs, 2 Charts, 2 Graphs.

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Amyloid beta emerges from below the neck to disable the brain.

• Authors : Kauwe, Grant¹ (AUTHOR); Tracy, Tara E.¹ (AUTHOR)

• Source: PLoS Biology. 9/15/2021, Vol. 19 Issue 9, p1-4. 4p. 1 Diagram.

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If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?

• Authors : Haass, Christian^1,2,3 (AUTHOR) ; Selkoe, Dennis⁴ (AUTHOR)

• Source: PLoS Biology. 7/21/2022, Vol. 20 Issue 7, p1-15. 15p. 1 Black and White Photograph, 1 Diagram, 1 Chart, 1 Graph.

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The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactions.

• Authors : Kessissoglou, Irini A.¹ (AUTHOR); Langui, Dominique¹ (AUTHOR); Hasan, Amr² (AUTHOR)

• Source: PLoS Biology. 12/8/2020, Vol. 18 Issue 12, p1-24. 24p. 1 Diagram, 9 Graphs.

تفاصيل العنوان

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.

• Authors : Rikesh M Rajani; Robert Ellingford; Mariam Hellmuth

Subjects: Biology (General); QH301-705.5

• Source: PLoS Biology, Vol 22, Iss 7, p e3002727 (2024)

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Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer's disease.

• Authors : Spieth L; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Oligodendroglia*/Oligodendroglia*/Oligodendroglia*/metabolism

• Source: PLoS biology [PLoS Biol] 2024 Sep 12; Vol. 22 (9), pp. e3002798. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.

• Authors : Wenping Zeng; Canjun Li; Ruikun Wu

Subjects: Biology (General); QH301-705.5

• Source: PLoS Biology, Vol 22, Iss 4, p e3002591 (2024)

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